دانلود مقالات ISI درباره دامنه SH2 + ترجمه فارسی

Solution structure of SHIP2 SH2 domain and its interaction with a phosphotyrosine peptide from c-MET

Keywords: دامنه SH2; INPPL1; HGFR; SH2 domain; Solution NMR structure; Tyrosine phosphorylation;

دانلود رایگان متن کامل مقاله ISI 28 صفحه سال انتشار : 2018 سفارش ترجمه

Screening and biological evaluation of a novel STAT3 signaling pathway inhibitor against cancer

Keywords: دامنه SH2; STAT3; SH2 domain; Inhibitor; Cancer; Anticancer drug; Virtual screening;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Cell confluence induces switching from proliferation to migratory signaling by site-selective phosphorylation of PDGF receptors on lipid raft platforms

Keywords: دامنه SH2; DAG; diacylglycerol; GM1; monosialotetrahexosylganglioside; GRB2; growth factor receptor binding protein-2; IP3; inositol 1,4,5-trisphosphate; PDGF; platelet-derived growth factor; PDGF-BB; homodimer of the B isoform of platelet derived growth factor); PD

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular cloning and characterization of a tyrosine phosphatase from Monosiga brevicollis

Keywords: دامنه SH2; Tyrosine phosphatase; SHP; SH2 domain; RNA splicing; Enzyme kinetics; Monosiga brevicollis;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Intracellular targets for a phosphotyrosine peptidomimetic include the mitotic kinesin, MCAK

Keywords: دامنه SH2; Signal transduction; SH2 domain; Drug delivery; Peptidomimetic; Kinesin; MCAK;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Abi1, a critical molecule coordinating actin cytoskeleton reorganization with PI-3 kinase and growth signaling

Keywords: دامنه SH2; Actin cytoskeleton; WAVE complex; Abi1; PI-3 kinase; SH2 domain;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Perspective: Dynamics of receptor tyrosine kinase signaling complexes

Keywords: دامنه SH2; Receptor tyrosine kinase; SH2 domain; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Tyrosine kinase signaling and the emergence of multicellularity

Keywords: دامنه SH2; Tyrosine kinase; Phosphorylation; Evolution; Choanoflagellate; SH2 domain; SH3 domain;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Targeting BCR Tyrosine177 site with novel SH2-DED causes selective leukemia cell death in vitro and in vivo

Keywords: دامنه SH2; SH2 domain; DED domain; Growth factor receptor-bound protein 2; Ras; AKT

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

Beyond 'furballs' and 'dumpling soups' - towards a molecular architecture of signaling complexes and networks

Keywords: دامنه SH2; Abl; Abelson tyrosine-protein kinase 1; ADAP1; arf-GAP with dual PH domain-containing protein 1; AFM; atomic force microscopy; cAMP; cyclic adenosine monophosphate; ApoER2; apolipoprotein E receptor 2; BCAR1; breast cancer anti-estrogen resistance 1; p130

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Identification and structural basis for a novel interaction between Vav2 and Arap3

Keywords: دامنه SH2; GEF; guanine nucleotide exchange factor; GAP; GTPase-activating protein; SH2; Src homology 2; pY; phosphotyrosine; PV; pervanadate; MD; molecular dynamics; Vav2; Arap3; SH2 domain; NMR; Protein-peptide interaction; Complex structure;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Rpa43 and its partners in the yeast RNA polymerase I transcription complex

Keywords: دامنه SH2; RNA polymerase; Nucleolus; Fission yeast; Budding yeast; Rpa43; Rpa14; Protein phosphorylation; SH2 domain; KOW domain;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Design and synthesis of a potential SH2 domain inhibitor bearing a stereodiversified 1,4-cis-enediol scaffold

Keywords: دامنه SH2; cis-Enediol; SH2 domain; Stereodiversified; Alkynylation;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Benzopyrazine derivatives: A novel class of growth factor receptor bound protein 7 antagonists

Keywords: دامنه SH2; Grb7; Adapter protein; SH2 domain; Benzopyrazines; Cancer cells; Similarity search; Virtual screening; ITC; Thermofluor; Melting point shift assay; Cellular growth assay;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2011 سفارش ترجمه

The C. elegans nck-1 gene encodes two isoforms and is required for neuronal guidance

Keywords: دامنه SH2; NCK; Axon guidance; Cell movement; C. elegans; Adaptor protein; SH2 domain; SH3 domain; NCK isoforms;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation

Keywords: دامنه SH2; Dictyostelium; SH2 domain; Adaptor protein; DIF-1; Prestalk; Basal disc;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2011 سفارش ترجمه

Design, synthesis, and in vitro characterization of novel hybrid peptidomimetic inhibitors of STAT3 protein

Keywords: دامنه SH2; STAT3; Peptidomimetics; SH2 domain; Molecular recognition; Anti-cancer drugs; Protein-protein interactions;

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2011 سفارش ترجمه

Fusion protein based on Grb2-SH2 domain for cancer therapy

Keywords: دامنه SH2; EGFR; SH2 domain; Grb2; Cancer therapy;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2010 سفارش ترجمه

P120-Ras GTPase activating protein (RasGAP): A multi-interacting protein in downstream signaling

Keywords: دامنه SH2; Ras; p120-RasGAP; SH2 domain; SH3 domainp120-RasGAP, Ras GTPase activating protein; GDP, guanosine diphosphate; GTP, guanosine triphosphate; GTPase, guanosine triphosphatase; GAP, GTPase-activating proteins; Dok, downstream of tyrosine kinase; PI-3K, phos

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2009 سفارش ترجمه

Synthesis and evaluation of phosphopeptides containing iminodiacetate groups as binding ligands of the Src SH2 domain

Keywords: دامنه SH2; IDA, iminodiacetate; F-GpYEEI, fluorescein-labeled GpYEEI; FP, fluorescence polarization; CD, circular dichroismPhosphopeptides; Metal chelation; Iminodiacetate group; SH2 domain; UV titration; Fluorescence polarization; Circular dichroism

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

BCAR3 regulates EGF-induced DNA synthesis in normal human breast MCF-12A cells

Keywords: دامنه SH2; BCAR3; Cas; Microinjection; EGF; Insulin; IGF-1; DNA synthesis; SH2 domain

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

A high-throughput assay for signal transducer and activator of transcription 5b based on fluorescence polarization

Keywords: دامنه SH2; Fluorescence polarization; Assay development; STAT5b; SH2 domain

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

A2 isoform of mammalian translation factor eEF1A displays increased tyrosine phosphorylation and ability to interact with different signalling molecules

Keywords: دامنه SH2; eEF1A1; eEF1A2; SH2 domain; SH3 domain; Shp2

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

SOCS regulation of the JAK/STAT signalling pathway

Keywords: دامنه SH2; Cytokine signalling; SOCS; SH2 domain; SOCS box; Inflammation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

New syntheses of tetrazolylmethylphenylalanine and O-malonyltyrosine as pTyr mimetics for the design of STAT3 dimerization inhibitors

Keywords: دامنه SH2; STAT3; pTyr mimetics; Inhibitors; SH2 domain; Cancer

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2007 سفارش ترجمه

Structural and energetic aspects of Grb2-SH2 domain-swapping

Keywords: دامنه SH2; Grb2; SH2 domain; Domain-swapping; Dimerization; Crystallography

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Cooperative activation of Src family kinases by SH3 and SH2 ligands

Keywords: دامنه SH2; Src; Tyrosine kinase; SH3 domain; SH2 domain; Cooperativity;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2007 سفارش ترجمه

Defining SH2 domain and PTP specificity by screening combinatorial peptide libraries

Keywords: دامنه SH2; SH2 domain; PTP; Combinatorial peptide library; Sequence specificity; Partial edman degradation; Phosphotyrosine; Protein–protein interaction; Signal transduction

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

TSAd interacts with Smad2 and Smad3

Keywords: دامنه SH2; Smad2; Smad3; TSAd; Lad; SH2 domain; GST-pull-down; Co-immunoprecipitation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2006 سفارش ترجمه

Structural Basis for Phosphotyrosine Recognition by the Src Homology-2 Domains of the Adapter Proteins SH2-B and APS

Keywords: دامنه SH2; adapter proteins; SH2 domain; Jak2; insulin receptor; crystal structureITC, isothermal titration calorimetry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Mutational analysis reveals separable DNA binding and trans-activation of Drosophila STAT92E

Keywords: دامنه SH2; JAK; STAT; SH2 domain; DNA binding; Transcriptional activation

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

A new efficient enantioselective synthesis of malonylphenylalanyl and malonylmethylphenylalanyl derivatives suitable for solid phase peptide synthesis

Keywords: دامنه SH2; Enantioselective synthesis; Phosphotyrosine mimetics; SH2 domain;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2005 سفارش ترجمه

Tyrosine-phosphorylated Hic-5 inhibits epidermal growth factor-induced lamellipodia formation

Keywords: دامنه SH2; Hic-5; hydrogen peroxide-inducible clone-5; EGF; epidermal growth factor; PDGF; platelet-derived growth factor; ARA55; androgen receptor associated protein 55; ECM; extracellular matrix; EMT; epithelial-mesenchymal transition; PBS2; paxillin binding sub

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه

Distinct Grb10 domain requirements for effects on glucose uptake and insulin signaling

Keywords: دامنه SH2; Grb10; growth factor receptor-binding protein 10; EGF; epidermal growth factor; SH2; Src homology 2; PH; pleckstrin homology; BPS; between PH and SH2; IGF-I; insulin-like growth factor-I; GIGYF; Grb10-interacting GYF protein; IRS; insulin receptor substra

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2005 سفارش ترجمه