Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Airway inflammation; Airway remodeling; Anti-muscarinic drug; Cholinergic regulation; Non-neuronal ACh; ACh; acetylcholine; ASM; airway smooth muscle; cAMP; cyclic adenosine monophosphate; ChAT; choline acetyltransferase; CHT1; high-affinity choline trans
مقالات ISI مبدل سیگنال و فعال کننده رونویسی 1 (ترجمه نشده)
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Keywords: مبدل سیگنال و فعال کننده رونویسی 1; APC; antigen presenting cell; APOBEC; apolipoprotein B mRNA editing enzyme catalytic polypeptide-like; BRCA1/2; breast cancer 1/2; BCSS; breast cancer specific survival; B2M; β-2-microglobulin; CAF; cancer associated fibroblast; CCL; chemokine ligand; CD
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Cancer metabolism; Combinatory therapy; Glutaminase isoenzymes; Glutamine; Glutaminase inhibitors; Metabolic reprogramming; DON; 6-diazo-5-oxy-L-norleucine; EATC; Ehrlich ascites tumour cells; ERK; extracellular signal-regulated kinases; GA; glutaminase;
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; GOF; Gain-of-function; STAT1; Signal transducer and activator of transcription 1; CMCD; Chronic mucocutaneous candidiasis disease; CCD; Coiled-coiled domain; DBD; DNA-binding domain; LOF; Loss-of-function; AR; Autosomal recessive; AD; Autosomal dominant
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; A-ADSCs; Apoptotic adipose stem cells; ACE; Angiotensin-converting enzyme.; ADSCs; Adipose-derived mesenchymal stem cells; AFSCs; Amniotic fluid stem cells; AKI; Acute kidney injury; ALF; Acute liver failure; ALI; Acute lung injury; ALT; Alanine transamin
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; ACTB; beta-actin; ATF4; activating transcription factor 4; BGLAP; osteocalcin; COL1A1; collagen type I alpha 1; FN1; fibronectin; IBSP; bone sialoprotein 2; IFN-γ; interferon-γ; IL; interleukin; RUNX2; runt-related transcription factor 2; SATB2; special
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Epstein-Barr virus; human herpes virus 4; latency; infectious mononucleosis; papular acrodermatitis of childhood; oral hairy leukoplakia; hydroa vacciniforme; nonsexually related acute genital ulcers; histiocytic necrotizing lymphadenitis; lymphoprolifera
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; BCR-ABL; breakpoint cluster region-Abelson tyrosine-protein kinase; CD95/FAS; cluster of differentiation 95/cell surface death receptor; DDR1; discoidin domain receptor tyrosine kinase 1; EGFR; epidermal growth factor receptor tyrosine kinase; EF1A2; euka
Cyclic analogue of S-benzylisothiourea that suppresses kynurenine production without inhibiting indoleamine 2,3-dioxygenase activity
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Kynurenine; Inhibitor; Indoleamine 2; 3-Dioxygenase; Signal transducer and activator of transcription 1; Immunological cancer treatment;
Quercetin inhibits the poly(dA:dT)-induced secretion of IL-18 via down-regulation of the expressions of AIM2 and pro-caspase-1 by inhibiting the JAK2/STAT1 pathway in IFN-γ-primed human keratinocytes
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Quercetin; IL (interleukin)-18; AIM (absent in melanoma) 2; Inflammasome; Keratinocytes; JAK/STAT pathway; IL-18; Interleukin (IL)-18; HEKn; Human primary epidermal keratinocytes from neonatal foreskin; IFN-γ; interferon-γ; AIM2; absent in melanoma 2; A
Cathelicidin-WA polarizes E. coli K88-induced M1 macrophage to M2-like macrophage in RAW264.7 cells
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; CWA; cathelicidin-WA; AMP; antimicrobial peptide; STAT1; signal transducer and activator of transcription 1; p-STAT1; phosphorylated signal transducer and activator of transcription 1; STAT6; signal transducer and activator of transcription 6; p-STAT6; ph
Regulation of cancer immune escape: The roles of miRNAs in immune checkpoint proteins
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Immune checkpoint proteins (ICPs); miRNAs; Cancer immune escape; Antigen-MHC; antigen-major histocompatibility complex; ICPs; immune checkpoint proteins; 3â²UTR; 3â² untransltated region; PD-1; programmed cell death protein; Tregs; regulatory T cells; H
8-Oxoguanine DNA glycosylase 1: Beyond repair of the oxidatively modified base lesions
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; ROS; reactive oxygen species; 8-oxoG; 7, 8-dihydro-8-oxoguanine; OGG1; 8-oxoguanine DNA glycosylase 1; BER; base excision repair; OGG1-BER; OGG1-initiated DNA base excision repair; IIR; innate immune response; TNFα; Tumor necrosis factor alpha; NF-κB; N
IL-6 family cytokines: Key inflammatory mediators as biomarkers and potential therapeutic targets
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; BALF; bronchoalveolar lavage fluid; CAC; colitis-associated cancer; CAF; cancer associated fibroblast; ccRCC; clear cell renal cell carcinoma; CLC; cardiotrophin-like cytokine; CML; chronic myeloid leukemia; CNTF; ciliary neurotrophic factor; COPD; chroni
Heat shock protein B1 is required for the prolactin-induced cytoprotective effects on pancreatic islets
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Apoptosis; Diabetes; Human islets; Islet transplantation; Prolactin; Survival; Mouse islets; AG490; Tyrphostin AG490; BAX; BCL2-associated X protein; BCL2; B cell CLL/lymphoma 2; BCLxL; BCL extra large; DM1; Type 1 diabetes mellitus; FCS; Fetal calf serun
Novel signal transducer and activator of transcription 1 mutation disrupts small ubiquitin-related modifier conjugation causing gain of function
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Signal transducer and activator of transcription 1; gain of function; sumoylation; small ubiquitin-related modifier; IFN-γ; Rhodococcus species infection; CMC; Chronic mucocutaneous candidiasis; GFP; Green fluorescent protein; GOF; Gain of function; IP10
ATF3 and PRAP1 play important roles in cisplatin-induced damages in microvascular endothelial cells
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; GO; Gene Ontology; KEGG; Kyoto Encyclopedia of Genes and Genomes; DEGs; differentially expressed genes; CDDP; cisplatin; CVD; cardiovascular disease; ATF3; Activating Transcription Factor 3; PRAP1; proline-rich acidic protein 1; HMEC-1; human microvascula
Benzo(a)pyrene attenuates the pattern-recognition-receptor induced proinflammatory phenotype of murine macrophages by inducing IL-10 expression in an aryl hydrocarbon receptor-dependent manner
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Ab; antibody; AhR; aryl hydrocarbon receptor; APC; antigen-presenting cell; ARNT; AhR nuclear translocator; BaP; benzo(a)pyrene; BMDCs; bone-marrow derived dendritic cells; BMMs; bone-marrow derived macrophages; CD; cluster of differentiation; CYP 450; cy
Sustained anti-inflammatory effects of TGF-β1 on microglia/macrophages
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; bFGF; basic fibroblast growth factor; Contra; contralateral cortex; DAMPs; damage-associated molecular patterns; dpr; days post-reperfusion; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HGF; hepatocyte growth factor; HMGB1; high mobility group box 1;
MicroRNA-214 inhibits the osteogenic differentiation of human osteoblasts through the direct regulation of baculoviral IAP repeat-containing 7
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; BIRC7; baculoviral IAP repeat-containing 7; STAT1; signal transducer and activator of transcription 1; ALP; alkaline phosphatase; col1α1; collagen type I α1; Runx2; runt related transcription factor 2; MiR-214; BIRC7; Osteoblasts; Osteogenic differentia
Identification of an IRF-1 splicing transcript in APL cells sharing similar transactivation activity of the full length one
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; IRF; interferon regulatory factor; IFN; interferon; DBD; DNA-binding domain; ISRE; interferon stimulated response element; IL4; interleukin 4; MDS; myelodysplastic syndrome; ATRA; all-trans retinoic acid; APL; acute promyelocytic leukemia; STAT1; signal t
Research reportInterferon (IFN)-induced protein 35 (IFI35) negatively regulates IFN-β-phosphorylated STAT1-RIG-I-CXCL10/CCL5 axis in U373MG astrocytoma cells treated with polyinosinic-polycytidylic acid
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; IFN; interferon; IFI; IFN-induced protein; ISG; IFN-stimulated gene; poly IC; polyinosinic-polycytidylic acid; RIG-I; retinoic acid-inducible gene-I; TLR3; Toll-like receptor 3; STAT1; signal transducer and activator of transcription 1; Astrocytes; TLR3;
Effects of hypnotic bromovalerylurea on microglial BV2 cells
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; NO; ATP; Microglia; Macrophage; Rotenone; ALI; acute lung injury; AMs; alveolar macrophages; BU; bromovalerylurea; JNK; c-Jun N-terminal kinases; cDNA; complementary DNA; Dex; dexamethasone; DMEM; Dulbecco's Modified Eagle Medium; E. coli; Escherichia col
Time-course microarrays reveal early activation of the immune transcriptome in a choline-deficient mouse model of liver injury
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; CD; choline deficient; NAFLD; nonalcoholic fatty liver disease; NASH; nonalcoholic steatohepatitis; VLDL; very low density lipoprotein; PC; phosphatidylcholine; Stat1; signal transducer and activator of transcription 1; FADS; fatty acid desaturases; ELOVL
Kr-POK (ZBTB7c) regulates cancer cell proliferation through glutamine metabolism
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Kr-POK; kidney cancer related POZ domain and Krüppel-like protein; GLS1; glutaminase; STAT1; signal transducer and activator of transcription 1; PIAS1; protein inhibitor of activated STAT1; BPTES; bis-2-(5-phenylacetamido-1,2,4-thiadiazol-2-yl) ethyl sul
IFN-γ orchestrates mesenchymal stem cell plasticity through the signal transducer and activator of transcription 1 and 3 and mammalian target of rapamycin pathways
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; IFN-γ; immunomodulation; T cells; mesenchymal stem cells; mammalian target of rapamycin; signal transducer and activator of transcription 1; signal transducer and activator of transcription 3; CUC; Cucurbitacin I; DTH; Delayed-type hypersensitivity; ERK
Label-free quantitative proteomics unravels the importance of RNA processing in glioma malignancy
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; 1PRPF8; pre-mRNA splicing factor 8; AGRN; agrin; DTT; dithiothreitol; EGFR; epidermal growth factor receptor; FDR; false discovery rate; FGF1; Fibroblast Growth Factor 1; FTH1; Ferritin Heavy chain; GBM; glioblastoma; HPLC; high-pressure liquid chromatogr
Impaired natural killer cell functions in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Natural killer cells; cytotoxic activity; IL-15; signal transducer and activator of transcription 1; signal transducer and activator of transcription 5; candidiasis; ChIP; Chromatin immunoprecipitation; CMCD; Chronic mucocutaneous candidiasis disease; E/T
Controlling the pro-inflammatory function of 6-sulfo LacNAc (slan) dendritic cells with dimethylfumarate
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; DMF; dimethylfumarate; FAE; fumaric acid ester; GSH; glutathione; slanDC; 6-sulfo LacNAc-expressing dendritic cells; Th17; T helper cells producing interleukin 17; Th1; T helper cells producing interferon gamma; TNF-α; tumor necrosis factor alpha; MS;
BH3-only protein BIM: An emerging target in chemotherapy
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; A1; Bcl-2-related protein A1; Apaf-1; Apoptotic protease-activating factor 1; ASK1; Apoptosis Signal Regulated Kinase 1; Bad; Bcl-2 associated agonist of cell death; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-associated X protein; Bcl-2; B-cell l
The roles of subcellularly located EGFR in autophagy
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; AMPK; AMP-activated protein kinase; ATG; autophagy-related; BCL2; B-cell lymphoma 2; BCL2L1; BCL2 like 1; BNIP3; BCL2/Adenovirus E1B-binding protein Nip3; CME; clathrin-mediated endocytosis; cytoSTAT3; cytoplasmic STAT3; Dsbs; double strand breaks; ECD; e
Interferon-γ Protects from Staphylococcal Alpha Toxin-Induced Keratinocyte Death through Apolipoprotein L1
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; AD; atopic dermatitis; ADAM10; a disintegrin and metalloproteinase 10; ApoL1; apolipoprotein L1; IFN; interferon; IL; interleukin; LC3; light chain 3; LDH; lactate dehydrogenase; RT-PCR; real-time PCR; SiRNA; small interfering RNA; STAT1; signal transduce
E3 ubiquitin ligase NKLAM ubiquitinates STAT1 and positively regulates STAT1-mediated transcriptional activity
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; NKLAM; natural killer lytic-associated molecule; STAT1; signal transducer and activator of transcription 1; RBR; RING in between RING; JAK1; Janus kinase 1; IFNγ; interferon gamma; IFNGR; interferon gamma receptor; GAS; gamma interferon activation sequen
Potential role of 8-oxoguanine DNA glycosylase 1 as a STAT1 coactivator in endotoxin-induced inflammatory response
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; BER; base excision repair; ChIP; chromatin immunoprecipitation; COX-2; cyclooxygenase-2; EAE; experimental autoimmune encephalomyelitis; faPyG; 2,6-diamino-4-hydroxy-5-formamidopyrimidine; GAS; gamma-interferon activation site; iNOS; inducible nitric oxid
Optimizing novel implant formulations for the prolonged release of biopharmaceuticals using in vitro and in vivo imaging techniques
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; DLS; Dynamic light scattering; DOL; Degree of labeling; FCS; Fetal calf serum; GAPDH; Glyceraldehyde 3-phosphate dehydrogenase; HA; Hyaluronan; IFN; Interferon; i.m.; Intramuscular; ISG; Interferon stimulated gene; IVIVC; In vitro-in vivo-correlation; LN;
Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5â²AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long
A2b adenosine signaling represses CIITA transcription via an epigenetic mechanism in vascular smooth muscle cells
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; CIITA; class II transactivator; GCN5; general control of amino acid synthesis protein 5; PCAF; p300-and-CBP-associated factor; STAT1; signal transducer and activator of transcription 1; VSMC; vascular smooth muscle cell; WDR5; WD repeat-containing protein
17β-Estradiol enhances the activation of IFN-α signaling in B cells by down-regulating the expression of let-7e-5p, miR-98-5p and miR-145a-5p that target IKKε
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; SLE; systemic lupus erythematosus; IFN-α; interferon-α; TLR; Toll like receptor; ER; estrogen receptor; IKKε; inhibitor of kappa B kinase epsilon; UTR; untranslated region; si-ERα; small interfering RNA specific to ERα; si-ERβ; small interfering RNA
Asthma and lower airway diseaseIL-27 and type 2 immunity in asthmatic patients: Association with severity, CXCL9, and signal transducer and activator of transcription signaling
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Asthma; IL-27; IL-13; CXCL9; epithelial cells; signal transducer and activator of transcription 1; signal transducer and activator of transcription 3; ALI; Air-liquid interface; BAL; Bronchoalveolar lavage; Feno; Fraction of exhaled nitric oxide; GAPDH; G
Chitosan polyplex nanoparticle vector for miR-145 expression in MCF-7: Optimization by design of experiment
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; miR-145; Chitosan; Design of experiment; miRNA; micro RNA; Mw; molecular weight; N/P; polymer amine to DNA phosphate ratio; RNAi; RNA interfering; siRNA; small interfering RNA; shRNA; short hairpin RNA; IGF-IR; type 1 insulin like growth factor receptor;
Zhankuic acid A as a novel JAK2 inhibitor for the treatment of concanavalin A-induced hepatitis
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Zhankuic acid A (PubChem CID: 10004842); Dexamethasone (PubChem CID: 5743); Ruxolitinib (PubChem CID: 25126798); Taiwanofungus camphoratus; Anti-inflammation; Interferon-γ; Signal transducer and activator of transcription 1; Interferon regulatory factor-
Interferon-gamma induced cell death: Regulation and contributions of nitric oxide, cJun N-terminal kinase, reactive oxygen species and peroxynitrite
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; AG; aminoguanidine; BrdU; bromodeoxyuridine; DAF2DA; 4, 5-diaminofluorescein diacetate; DCFDA; 2â², 7â²-dichlorofluorescin diacetate; DHR123; dihydrorhodamine 123; FeTPPS; 5,10,15,20-tetrakis(4-sulfonatophenyl) porphyrinato iron (III), chloride; FITC; f
Illicium verum extract suppresses IFN-γ-induced ICAM-1 expression via blockade of JAK/STAT pathway in HaCaT human keratinocytes
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Illicium verum; Interferon-gamma; Intercellular adhesion molecule-1; Janus kinase; Signal transducer and activator of transcription 1;
Modulation of the peroxiredoxin system by cytokines in insulin-producing RINm5F cells: Down-regulation of PRDX6 increases susceptibility of beta cells to oxidative stress
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Akt; v-akt murine thymona viral oncogene homolog 1; IFN-gamma; interferon gamma; IL-1beta; interleukin 1 beta; JNK; c-Jun N-terminal kinase; NF-kappaB; Nuclear factor of kappa light polypeptide gene enhancer in B cells 1; PI3K; phosphatidylinositol 3'ki
Human T Cell Leukemia Virus Type I Tax-Induced IκB-ζ Modulates Tax-Dependent and Tax-Independent Gene Expression in T Cells
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Abs; antibodies; AP-1; activator protein 1; ATL; adult T cell leukemia; Bcl3; B cell CLL/lymphoma 3; CBB; Coomassie brilliant blue; CREB; cyclic adenosine 3â²,5â²-monophosphate response element-binding protein; EGFP; enhanced green fluorescent protein;
Dominant gain-of-function STAT1 mutations in FOXP3 wild-type immune dysregulation-polyendocrinopathy-enteropathy-X-linked-like syndrome
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Signal transducer and activator of transcription 1; immune dysregulation-polyendocrinopathy-enteropathy-X-linked; forkhead box protein 3; regulatory T cell; chronic mucocutaneous candidiasis; aneurysms; APC; Antigen-presenting cell; CFSE; Carboxyflu
Signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations and disseminated coccidioidomycosis and histoplasmosis
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; Signal transducer and activator of transcription 1; IFN-γ; progressive multifocal leukoencephalopathy; Histoplasma capsulatum; Coccidioides immitis; thrush; CMC; Chronic mucocutaneous candidiasis; CSF; Cerebrospinal fluid; CT; Computed tomography; DMA; M
New primers for methylation-specific polymerase chain reaction enhance specificity of detecting STAT1 methylation
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; methylation; polymerase chain reaction; signal transducer and activator of transcription 1
A conserved regulatory element located far downstream of the gls locus modulates gls expression through chromatin loop formation during myogenesis
Keywords: مبدل سیگنال و فعال کننده رونویسی 1; 3C; chromosome conformation capture; 5.5URR; 5.5Â kb upstream regulatory region; DM; differentiation medium; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; GLS; glutaminase; GM; growth medium; IRF; interferon regulatory factor; MAZ; MYC-associated zinc