دانلود مقالات ISI درباره Sirt1 + ترجمه فارسی

Epigallocatechin-3-gallate increases autophagy signaling in resting and unloaded plantaris muscles but selectively suppresses autophagy protein abundance in reloaded muscles of aged rats

Keywords: ATG; autophagy-related gene; Bak1; BCL2-antagonist/killer 1; Bcl-2; B-cell lymphoma 2; Bcl-XL; Bcl2-like 1; Beclin1; BCL2 interaction myosin/moesin like coiled-coil protein 1; Cdkn2A; cyclin-dependent kinase inhibitor 2A; Dapk1; death associated protein k

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway

Keywords: AMPK; adenosine 5′ monophosphate-activated protein kinase; Bax; Bcl-2 associated X protein; BBB; Basso, Beattie, and Bresnahan; DMEM; Dulbecco's Modified Eagle Medium; DMSO; dimethyl sulfoxide; HE; hematoxylin and eosin; LPS; lipopolysaccharides; PBS;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

Role of nutraceutical SIRT1 modulators in AMPK and mTOR pathway: Evidence of a synergistic effect

Keywords: SIRT1; AMPK; mTOR; Nutraceutical modulators; Synergistic effect;

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2017 سفارش ترجمه

The metalloproteinase ADAM10: A useful therapeutic target?

Keywords: APL; Acute Promyelocytic Leukemia; ADAM; A Disintegrin And Metalloproteinase; AP2; Adaptor Protein-2; AD; Alzheimer's Disease; Aβ; Amyloid beta; APP; Amyloid Precursor Protein; ACE; Angiotensin Converting Enzyme; APRIL; A Proliferation-Inducing Ligand; B

دانلود رایگان متن کامل مقاله ISI 52 صفحه سال انتشار : 2017 سفارش ترجمه

SIRT1 controls cell proliferation by regulating contact inhibition

Keywords: SIRT1; Contact inhibition; Cell proliferation; Malignant transformation; p27;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2016 سفارش ترجمه

Circulating SIRT1 inversely correlates with epicardial fat thickness in patients with obesity

Keywords: SIRT1; Epicardial fat; Obesity;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Clinicopathological significance of SIRT1 expression in colorectal cancer: A systematic review and meta analysis

Keywords: SIRT1; Colorectal cancer; Clinicopathological characteristics; Prognosis

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Beneficial effects of omega-3 and vitamin E coadministration on gene expression of SIRT1 and PGC1α and serum antioxidant enzymes in patients with coronary artery disease

Keywords: CAD; Omega-3; Vitamin E; SIRT1; PGC1α; Antioxidant enzymes;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Brachyury promotes tamoxifen resistance in breast cancer by targeting SIRT1

Keywords: Brachyury; SIRT1; Tamoxifen resistance; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-34a induces a senescence-like change via the down-regulation of SIRT1 and up-regulation of p53 protein in human esophageal squamous cancer cells with a wild-type p53 gene background

Keywords: EC; esophageal carcinoma; SA-β-Gal; senescence-associated β-galactosidase; SIRT1; Sirtuin1; ADR; adrmycin; PCR; polymerase chain reaction; PNUTS; phosphatase-1 nuclear targeting subunit; DMSO; dimethylsulfoxide; Esophageal squamous cancer cell; p53; miR

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Mst1 regulates hepatic lipid metabolism by inhibiting Sirt1 ubiquitination in mice

Keywords: Mst1; Sirt1; Non-alcoholic fatty liver disease; Oxidant stress;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

DJ-1 activates SIRT1 through its direct binding to SIRT1

Keywords: DJ-1; SIRT1; Deacetylase; p53;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

Treatment with the neurotoxic Aβ (25-35) peptide modulates the expression of neuroprotective factors Pin1, Sirtuin 1, and brain-derived neurotrophic factor in SH-SY5Y human neuroblastoma cells

Keywords: AD; Alzheimer's disease; Aβ; amyloid β; APP; amyloid precursor protein; Bdnf; brain-derived neurotrophic factor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; PBS; phosphate-buffered saline; Sirt1; Sirtuin 1; Amyloid β; Pin1; Sirtuin 1; Brain-deri

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

NS5ATP6 modulates intracellular triglyceride content through FGF21 and independently of SIRT1 and SREBP1

Keywords: NS5ATP6; FGF21; miR-577; SIRT1; SREBP1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Comparison of liver microRNA transcriptomes of Tibetan and Yorkshire pigs by deep sequencing

Keywords: miRNA; microRNA; TPL; Tibetan pig liver; YKL; Yorkshire pig liver; qPCR; quantitative real-time PCR; Stem-loop qPCR; stem-loop quantitative real-time PCR; Sirt1; Sirtuin type 1; PKM2; M2 isoform of pyruvate kinase; LXRα; Liver X receptor α; SR-BI; s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Basic nutritional investigationVitamin D decreases adipocyte lipid storage and increases NAD-SIRT1 pathway in 3T3-L1 adipocytes

Keywords: 1,25(OH)2D; Adipocyte; Lipid storage; Lipolysis; SIRT1; NAD; Obesity;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

CBX8 antagonizes the effect of Sirtinol on premature senescence through the AKT-RB-E2F1 pathway in K562 leukemia cells

Keywords: CBX8; SIRT1; RB-E2F1; Premature senescence; Leukemia; RB; retinoblastoma; β-gal; β-galactosidase; GFP; green fluorescent protein;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

NAMPT regulates senescence, proliferation, and migration of endothelial progenitor cells through the SIRT1 AS lncRNA/miR-22/SIRT1 pathway

Keywords: NAMPT; SIRT1; lncRNA; miR-22; Endothelial progenitor cells; Senescence;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol provides neuroprotection by inhibiting phosphodiesterases and regulating the cAMP/AMPK/SIRT1 pathway after stroke in rats

Keywords: Resveratrol; Stroke; SIRT1; AMPK; ATP; PDEs

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Ethyl pyruvate inhibits the acetylation and release of HMGB1 via effects on SIRT1/STAT signaling in LPS-activated RAW264.7 cells and peritoneal macrophages

Keywords: SIRT1; Inflammation; Sepsis; HMGB1; Ethyl pyruvate; STAT signal;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Evidence for possible role of melatonin in reducing oxidative stress in multiple sclerosis through its effect on SIRT1 and antioxidant enzymes

Keywords: Multiple sclerosis; Oxidative stress; Melatonin; SIRT1; MnSOD; Catalase;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Lin28a protects against postinfarction myocardial remodeling and dysfunction through Sirt1 activation and autophagy enhancement

Keywords: Lin28a; Sirt1; Myocardial infarction; MI; Autophagy; Apoptosis;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Research reportNrf2/antioxidant defense pathway is involved in the neuroprotective effects of Sirt1 against focal cerebral ischemia in rats after hyperbaric oxygen preconditioning

Keywords: Sirt1; sirtuin 1; HBO-PC; hyperbaric oxygen preconditioning; MCAO; middle cerebral artery occlusion; Nrf2; nuclear factor erythroid-2 related factor 2; SOD1; superoxide dismutase 1; HO-1; heme oxygenase 1; MDA; malondialdehyde; siRNA; short interfering RN

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Methylene blue alleviates experimental autoimmune encephalomyelitis by modulating AMPK/SIRT1 signaling pathway and Th17/Treg immune response

Keywords: MS; multiple sclerosis; MB; methylene blue; EAE; experimental autoimmune encephalomyelitis; CNS; central nervous system; IFN; interferon; NF-κB; nuclear factor kappa B; AMPK; AMP-activated protein kinase; SIRT1; silent mating-type information regulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Restoration of sirt1 function by pterostilbene attenuates hypoxia-reoxygenation injury in cardiomyocytes

Keywords: Ischemia-reperfusion injury; Pterostilbene; Cardiomyocyte apoptosis; Sirt1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-132 cause apoptosis of glioma cells through blockade of the SREBP-1c metabolic pathway related to SIRT1

Keywords: HMGCR, 3-hydroxy-3-methylglutaryl CoA reductase; FASN, fatty acid synthase; BDNF, brain derived neurotrophic factor; CREB, cAMP-response element binding proteinmicroRNA; SIRT1; Apoptosis; SREBP-1c; Lipid metabolism; Glioma

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 Gain of Function Does Not Mimic or Enhance the Adaptations to Intermittent Fasting

Keywords: SIRT1; caloric restriction; mitochondria

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 regulates accumulation of oxidized LDL in HUVEC via the autophagy-lysosomal pathway

Keywords: SIRT1; ox-LDL; Accumulation; HUVECs; Autophagy-lysosomal pathway;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Sirtuin 1 evaluation with a novel immunoassay approach based on TiO2–Au label and hyperbranched polymer hybrid

Keywords: SirT1; TiO2–Au nanocomposite; Hyperbranched polymer; Electrochemical; ImmunoassaySirT1, sirtuin 1; PNC, polymeric nanocomposite; TiO2, titanium dioxide; Au, gold; HAP, hyperbranched azo-polymer; Ab1#1, goat polyclonal anti-SirT1; Ab1#2, rabbit polyclonal

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Sirt1 is essential for resveratrol enhancement of hypoxia-induced autophagy in the type 2 diabetic nephropathy rat

Keywords: Diabetic nephropathy; Sirt1; Resveratrol; Autophagy; Hypoxia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

PPARα agonist, fenofibrate, ameliorates age-related renal injury

Keywords: Aging; Kidney; PPAR-α; SIRT1; AMPK; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 inhibits inflammatory response partly through regulation of NLRP3 inflammasome in vascular endothelial cells

Keywords: SIRT1; NLRP3 inflammasome; Inflammation; Endothelial cells; Cytokines;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Leptin contributes to long-term stabilization of HIF-1α in cancer cells subjected to oxygen limiting conditions

Keywords: Obesity; Mitochondria; Uncoupled respiration; UCP2; SIRT1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of microRNA-449a prevents IL-1β-induced cartilage destruction via SIRT1

Keywords: microRNA-449a; SIRT1; Chondrocytes; IL-1β; Osteoarthritis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Lactobacillus brevis T2102 suppresses the growth of colorectal cancer cells by activating SIRT1

Keywords: Lactic acid bacteria; SIRT1; Colorectal cancer; β-catenin; hTERTAPC, adenomatous polyposis coli; CR, calorie restriction; hTERT, human telomerase reverse transcriptase; LAB, lactic acid bacteria

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 mediates Sphk1/S1P-induced proliferation and migration of endothelial cells

Keywords: Sphk1; S1P; SIRT1; HUVEC; Proliferation; Migration;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Expression patterns of sirtuin 1-AMPK-autophagy pathway in chronic colitis and inflammation-associated colon neoplasia in IL-10-deficient mice

Keywords: Chronic inflammation; Colon carcinogenesis; IL-10-deficient mice; SIRT1; Autophagy

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Upregulation of MKP-7 in response to rosiglitazone treatment ameliorates lipopolysaccharide-induced destabilization of SIRT1 by inactivating JNK

Keywords: SIRT1; silent mating type information regulation 2 homolog 1; PPARγ; peroxisome proliferator-activated receptor γ; LPS; lipopolysaccharide; MKP-7; mitogen-activated protein kinase phosphatase-7; PGC-1α; peroxisome proliferator-activated receptor gamma

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2016 سفارش ترجمه

Altered cellular redox status, sirtuin abundance and clock gene expression in a mouse model of developmentally primed NASH

Keywords: NAFLD; non-alcoholic fatty liver disease; NASH; non-alcoholic steatohepatitis; HF; high fat; C; control; sirt1; sirtuin 1; sirt3; sirtuin 3; Clock; circadian locomotor output cycles kaput; Per2; Bmal1 (also called Arntl1), period 2; Cry2; cryptochrome 2;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 activator ameliorates the renal tubular injury induced by hyperglycemia in vivo and in vitro via inhibiting apoptosis

Keywords: Resveratrol; Diabetic nephropathy; HK-2 cells; SIRT1; p53; Apoptosis

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Acetylome study in mouse adipocytes identifies targets of SIRT1 deacetylation in chromatin organization and RNA processing

Keywords: SIRT1; Protein deacetylation; Mouse adipocyte; Chromatin structure; RNA processing

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 promotes epithelial-mesenchymal transition and metastasis in colorectal cancer by regulating Fra-1 expression

Keywords: Colorectal cancer; Metastasis; SIRT1; Epithelial-mesenchymal transition; Fra-1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Peroxisome proliferator-activated receptor-γ (PPARγ) agonist is neuroprotective and stimulates PGC-1α expression and CREB phosphorylation in human dopaminergic neurons

Keywords: PPARγ; PGC-1α; SIRT1; CREB; Dopaminergic neurons; Mitochondria; AC6; adenylyl cyclase 6; CRE; cAMP responsive element; CREB; cAMP responsive element-binding protein; FCCP; carbonyl cyanide 4-(trifluoromethoxy)phenylhydrazone; GW1929; N-(2-benzoylphenyl)

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1-AMPK crosstalk is involved in high glucose-dependent impairment of insulin responsiveness in primary rat podocytes

Keywords: Podocyte; Hyperglycemia; Insulin resistance; SIRT1; AMPK; Resveratrol;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Diminished levels of regulatory T cell subsets (CD8+Foxp3, CD4+Foxp3 and CD4+CD39+Foxp3) but increased Foxp3 expression in adipose tissue from overweight subjects

Keywords: Infiltrated lymphocytes; Sirt1; Treg cells; Foxp3; Overweight; PPAR-γ

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 activation attenuates diastolic dysfunction by reducing cardiac fibrosis in a model of anthracycline cardiomyopathy

Keywords: Diastolic dysfunction; Cardiac fibroblasts; Doxorubicin-induced cardiomyopathy; SIRT1; Resveratrol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

The metabolic sensor Sirt1 and the hypothalamus: Interplay between peptide hormones and pro-hormone convertases

Keywords: Sirt1; POMC; MSH; CRH; ACTH; Obesity;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Activation of the AMPK/Sirt1 pathway by a leucine-metformin combination increases insulin sensitivity in skeletal muscle, and stimulates glucose and lipid metabolism and increases life span in Caenorhabditis elegans

Keywords: AMPK; Sirt1; Insulin sensitivity; Leucine; Metformin; ACC; acetyl-CoA carboxylase; AICAR; 5-aminoimidazole-4-carboxamide ribonucleotide; AMPK; 5′ adenosine monophosphate-activated protein kinase; CREB; cAMP-responsive element binding protein; CRTC2; CRE

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 is a critical regulator of K562 cell growth, survival, and differentiation

Keywords: SIRT1; Deacetylase; K562 cells

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

MicroRNA-133b inhibits hepatocellular carcinoma cell progression by targeting Sirt1

Keywords: MiR-133b; Sirt1; Hepatocellular carcinoma; Proliferation; Apoptosis

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه