دانلود مقالات ISI درباره Sirt1 + ترجمه فارسی

Identification of Mediator Kinase Substrates in Human Cells using Cortistatin A and Quantitative Phosphoproteomics

Keywords: CDK8-Mediator; Mediator; SILAC; cholesterol; MED13; MED13L; SIRT1

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2016 سفارش ترجمه

Epigallocatechin gallate and mitochondria-A story of life and death

Keywords: ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; ALT; alanine aminotransferase; AMP; adenosine monophosphate; AP-1; activator protein-1; ASK1; apoptosis signal-regulating kinase 1; ATP; adenosine triphosphate; Bax; BCL2-Associated X Protein; Bc

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2016 سفارش ترجمه

CTRP9 induces mitochondrial biogenesis and protects high glucose-induced endothelial oxidative damage via AdipoR1 -SIRT1- PGC-1α activation

Keywords: CTRP9; PGC-1α; SIRT1; Mitochondrial biogenesis; AdipoR1;

دانلود رایگان متن کامل مقاله ISI 23 صفحه سال انتشار : 2016 سفارش ترجمه

Negative regulation of the FOXO3a transcription factor by mTORC2 induces a pro-survival response following exposure to ultraviolet-B irradiation

Keywords: mTOR; mammalian target of rapamycin; UVB; ultraviolet-B; NMSC; non-melanoma skin cancer; mTORC1; mTOR complex 1; mTOC2; mTOR complex 2; AKT/PKB; protein kinase B; SCC; squamous cell carcinoma; ERK; extracellular-signal-regulated kinases; MEK; mitogen-acti

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy: A double-edged sword in intervertebral disk degeneration

Keywords: IVD; intervertebral disk; NP; nucleus pulposus; AF; annulus fibrosus; CEPs; cartilaginous endplates; ECM; extracellular matrix; Col II; type II collagen; Col I; type I collagen; IDD; intervertebral disk degeneration; LBP; low back pain; miRNAs; microRNAs;

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Upregulation of microRNA-22 contributes to myocardial ischemia-reperfusion injury by interfering with the mitochondrial function

Keywords: MicroRNA-22; Cardiomyocyte; Mitochondria; Ischemia-reperfusion; Sirt1; PGC1α; p53;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

A conjugated fatty acid present at high levels in bitter melon seed favorably affects lipid metabolism in hepatocytes by increasing NAD+/NADH ratio and activating PPARα, AMPK and SIRT1 signaling pathway

Keywords: ACC; acetyl-CoA carboxylase; ACOX; acyl-CoA oxidase; AMPK; AMP-activated protein kinase; BMSO; bitter melon seed oil; c9,t11-CLA; cis-9, trans-11 isomer of conjugated linoleic acid; α-ESA; α-eleostearic acid; FASN; fatty acid synthase; FOXO1; forkhead b

دانلود رایگان متن کامل مقاله ISI 41 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol inhibits inflammatory signaling implicated in ionizing radiation-induced premature ovarian failure through antagonistic crosstalk between silencing information regulator 1 (SIRT1) and poly(ADP-ribose) polymerase 1 (PARP-1)

Keywords: AMH; anti-Müllerian hormone; COX-2; cyclooxygenase-2; IL; interleukin; iNOS; inducible nitric oxide synthase; NF-κB; nuclear factor kappa-B; PARP; poly(ADP-ribose) polymerase; POF; premature ovarian failure; PPARs; peroxisome proliferator-activated rece

دانلود رایگان متن کامل مقاله ISI 45 صفحه سال انتشار : 2016 سفارش ترجمه

Nutrient restriction of glucose or serum results in similar proteomic expression changes in 3D colon cancer cell cultures

Keywords: Nutrient restriction; Three dimensional cell culture; Autophagy; Apoptosis; Quantitative proteomics; Colorectal cancer; NR; nutrient restriction; FBS; fetal bovine serum; iTRAQ; isobaric tags for relative and absolute quantification; SIRT1; sirtuin 1; PIA

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

MEK1/2 inhibitors activate macrophage ABCG1 expression and reverse cholesterol transport-An anti-atherogenic function of ERK1/2 inhibition

Keywords: ABCG1; Atherosclerosis; LXR; MEK1/2; RCT; SIRT1;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

Shifting p53-induced senescence to cell death by TIS21/BTG2/Pc3 gene through posttranslational modification of p53 protein

Keywords: p53-S46 phosphorylation; p53-K-acetylations; miR34a; SIRT1; Bcl2; Proapoptotic genes;

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2016 سفارش ترجمه

How much successful are the medicinal chemists in modulation of SIRT1: A critical review

Keywords: SIRT1; Activators; Inhibitors; Resveratrol; SRT1720; Fluor de Lys assay;

دانلود رایگان متن کامل مقاله ISI 102 صفحه سال انتشار : 2016 سفارش ترجمه

SIRT1 mediated inhibition of VEGF/VEGFR2 signaling by Resveratrol and its relevance to choroidal neovascularization

Keywords: RPE; SIRT1; Resveratrol; VEGFR2; HIF-1α; CNV

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2015 سفارش ترجمه

Acetylcholinesterase inhibitors and compounds promoting SIRT1 expression from Curcuma xanthorrhiza

Keywords: AChE; acetylcholinesterase; SIRT1; silent information regulator two homologue 1; MIQ; minimum inhibitory quantity; PVDF; polyvinylidene fluoride; Curcuma xanthorrhiza; Zedoaraldehyde; Acetylcholinesterase inhibitory activity; SIRT1; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of SIRT1 on cellular apoptosis and steroidogenesis in bovine ovarian granulosa cells in vitro

Keywords: SIRT1; Granulosa cells; Apoptosis; Estradiol; Progesterone; SF-1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Effect of caloric restriction on the SIRT1/mTOR signaling pathways in senile mice

Keywords: Caloric restriction; SIRT1; mTOR; S6K1

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Resveratrol-induced SIRT1 activation promotes neuronal differentiation of human bone marrow mesenchymal stem cells

Keywords: Resveratrol; Bone marrow mesenchymal stem cells (BM-MSCs); Neuronal differentiation; Sirtuin1 (SIRT1); AMPK; AMP-activated protein kinase; BHA; butylated hydroxyanisole; BM-MSCs; bone marrow-mesenchymal stem cells; cAMP; cyclic AMP; ctrl-MSCs; control-MSC

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Novel thiourea-based sirtuin inhibitory warheads

Keywords: β-NAD+; β-nicotinamide adenine dinucleotide; 2′-O-AADPR; 2′-O-acyl-ADP-ribose; IC50; the inhibitor concentration at which an enzymatic reaction velocity is reduced by 50%; SPPS; solid phase peptide synthesis; RP-HPLC; reversed-phase high pressure li

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 gene is associated with cardiovascular disease in the Iranian population

Keywords: Sirtuin; SIRT1; Cardiovascular disease (CVD); Genetic polymorphism

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Insulin attenuates arsenic-induced neurite outgrowth impairments by activating the PI3K/Akt/SIRT1 signaling pathway

Keywords: Arsenic; Neurite outgrowth; Insulin; PI3K; Akt; SIRT1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Acetylated 8-oxoguanine DNA glycosylase 1 and its relationship with p300 and SIRT1 in lens epithelium cells from age-related cataract

Keywords: Age-related cataract (ARC); Oxidative damage; 8-Oxoguanine DNA glycosylase1 (OGG1); Acetylation; p300; SIRT1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Differential effect of estradiol and bisphenol A on Set8 and Sirt1 expression in prostate cancer

Keywords: BPA; Prostate; Set8; Sirt1

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

The Sirt1 activator SRT1720 attenuates angiotensin II-induced atherosclerosis in apoE−/− mice through inhibiting vascular inflammatory response

Keywords: SIRT1; SRT1720; Angiotensin II; NF-κB; STAT3; Atherosclerosis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Fisetin induces Sirt1 expression while inhibiting early adipogenesis in 3T3-L1 cells

Keywords: Adipocyte differentiation; Fisetin; Sirt1; 3T3-L1;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 deacetylates and stabilizes hypoxia-inducible factor-1α (HIF-1α) via direct interactions during hypoxia

Keywords: SIRT1; HIF-1α; Stabilization; Deacetylation; Interaction; Invasion;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Salvianolic acid B attenuates apoptosis and inflammation via SIRT1 activation in experimental stroke rats

Keywords: Salvianolic acid B; Ischemic stroke; SIRT1; Apoptosis; Inflammation

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Different effects of resveratrol on early and late passage mesenchymal stem cells through β-catenin regulation

Keywords: SIRT1; Resveratrol; Mesenchymal stem cells; Cellular senescence; β-catenin; CFU-F; colony-forming unit fibroblast; EP-MSC; early passage mesenchymal stem cell; DAPI; 4′,6-diamidino-2-phenylindole; DMEM-LG; Dulbecco's modified Eagle medium, low glucose;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Oxygen-dependent acetylation and dimerization of the corepressor CtBP2 in neural stem cells

Keywords: NSCs; Cortex; Neural development; Hypoxia; Sirt1; p53;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 regulates autophagy and diploidization in parthenogenetic haploid embryonic stem cells

Keywords: Parthenogenetic; Haploid embryonic stem cells; Sirt1; Autophagy; Oxidative stress; P53; TET3;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1: Role in cardiovascular biology

Keywords: SIRT1; Senescence; Cardiovascular biology; Expression regulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleRestoration of Wnt/β-catenin signaling attenuates alcoholic liver disease progression in a rat model

Keywords: Foxo3A; forkhead box O3; Wnt; wingless-type MMTV integration site family; ALD; alcoholic liver disease; SGK1; serum/glucocorticoid regulated kinase 1; Sirt1; sirtuin 1; LiCl; lithium chloride; Wnt; Alcoholic liver disease; Apoptosis; Foxo3A; SGK1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation

Keywords: NAM, nicotinamide; PKA, protein kinase A; CREB, cyclic AMP response-element-binding protein; Nampt, nicotinamide phosphoribosyltransferase; NMN, nicotinamide mononucleotide; PDE, phosphodiesteraseNicotinamide; Sirt1; NAD+;  Deacetylation; CAMP; PKA

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Inflammation and intracellular metabolism: new targets in OA

Keywords: Inflammation; Energy metabolism; Cartilage homeostasis; AMPK; SIRT1;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Hydrogen sulfide protects against apoptosis under oxidative stress through SIRT1 pathway in H9c2 cardiomyocytes

Keywords: H2S; hydrogen sulfide; H2O2; hydrogen peroxide; NaSH; sodium hydrogen sulfide; NO; nitric oxide; ROS; reactive oxygen species; SIRT1; Sirturn-1; HF; heart failure; Hydrogen sulfide; Oxidative stress; Sirtuin-1; Mitochondrial function;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Nicotinamide and resveratrol regulate bovine adipogenesis through a SIRT1-dependent mechanism

Keywords: Nicotinamide; Resveratrol; SIRT1; Bovine; Adipogenic differentiation;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Hypermethylation in gastric cancer

Keywords: 5-hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosine; ADAM23; ADAM metallopeptidase domain 23; APC; adenomatosis polyposis coli; ATP; adenosine-triphosphate; BCL6B; B-Cell CLL/Lymphoma 6, Member B; BGS; bisulfite genomic sequencing; BMP-2; bone morphoge

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Divalproex sodium enhances the anti-leukemic effects of imatinib in chronic myeloid leukemia cells partly through SIRT1

Keywords: Chronic myeloid leukemia; Imatinib; Divalproex sodium; Bcr-Abl; SIRT1;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

α-Lipoic acid treatment increases mitochondrial biogenesis and promotes beige adipose features in subcutaneous adipocytes from overweight/obese subjects

Keywords: α-Lip; α-Lipoic acid; LDH; lactate dehydrogenase; mtDNA; mitochondrial DNA; Sirt1; Sirtuin 1; PGC-1α; peroxisome proliferator-activated receptor gamma, coactivator 1 alpha; Nrf1; nuclear respiratory factor 1; Tfam; mitochondrial transcription factor; C

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

WRN translocation from nucleolus to nucleoplasm is regulated by SIRT1 and required for DNA repair and the development of chemoresistance

Keywords: WRN; SIRT1; Cisplatin; DNA damage; DNA repair; Chemoresistance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Cardiovascular pharmacologyKaempferol protects cardiomyocytes against anoxia/reoxygenation injury via mitochondrial pathway mediated by SIRT1

Keywords: Kaempferol; Anoxia/reoxygenation; SIRT1; Mitochondrial; Cardiomyocyte;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Distinctive role of SIRT1 expression on tumor invasion and metastasis in breast cancer by molecular subtype

Keywords: Breast cancer; SIRT1; Metastasis; Invasion; Subtype

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

SIRT1 inhibition in pancreatic cancer models: Contrasting effects in vitro and in vivo

Keywords: 6-Chloro-2,3,4,9-tetrahydro-1H-Carbazole-1-carboxamide (EX527) (PubChem CID: 5113032)Pancreatic cancer; EX527; SIRT1; Sirtuin; Gemcitabine; Tumour resistance

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Simiao pill ameliorates renal glomerular injury via increasing Sirt1 expression and suppressing NF-κB/NLRP3 inflammasome activation in high fructose-fed rats

Keywords: Simiao pill; Fructose; Renal glomerular injury; Sirt1; NF-κB; NLRP3 inflammasome;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of miR-34a/SIRT1/p53 signaling contributes to cochlear hair cell apoptosis: implications for age-related hearing loss

Keywords: MicroRNA; SIRT1; p53; Cochlea; Presbycusis;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Activation of PPAR alpha by fenofibrate inhibits apoptosis in vascular adventitial fibroblasts partly through SIRT1-mediated deacetylation of FoxO1

Keywords: PPARα; SIRT1; FoxO1; Apoptosis; Vascular adventitial fibroblasts;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Nutraceutical activators of AMPK/Sirt1 axis inhibit viral production and protect neurons from neurodegenerative events triggered during HSV-1 infection

Keywords: HSV-1; AMPK; Sirt1; p53; Resveratrol; Quercetin

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Investigating the role of Sirt1-modulated oxidative stress in relation to benign paroxysmal positional vertigo and Parkinson's disease

Keywords: Benign paroxysmal positional vertigo; Parkinson's disease; SIRT1; Oxidative stress;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleSIRT1 regulates oncogenesis via a mutant p53-dependent pathway in hepatocellular carcinoma

Keywords: HCC; hepatocellular carcinoma; RFS; relapse-free survival; OS; overall survival; mTOR; mammalian target of rapamycin; SIRT1; silent mating-type information regulation 2 homolog 1; AMPK; AMP-activated protein kinase; ROS; reactive oxygen species; ACC; acet

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

The natural phytochemical dehydroabietic acid is an anti-aging reagent that mediates the direct activation of SIRT1

Keywords: Longevity; Dehydroabietic acid; SIRT1; Phytochemical; Binding model;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Sirt1 mediates the effects of a short-term high-fat diet on the heart

Keywords: Sirt1; PPARα; High-fat diet; Cardiac dysfunction; Metabolism;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه