Keywords: aPKC; atypical protein kinase C; CBP; CREB binding protein; ChREBP; carbohydrate response element-binding protein; CREB; cAMP response element-binding protein; CRTC2; CREB-regulated transcription coactivator 2; FA; fatty acid; GIPR; glucose-dependent insu
مقالات ISI (ترجمه نشده)
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Keywords: AGE; advanced glycation end products; AICAR; 5-Aminoimidazole-4-carboxamide ribonucleotide; AMPK; 5â² adenosine monophosphate-activated protein kinase; APC; antigen-presenting cell; Atg7; autophagy-related gene 7; ATP; adenosine triphosphate; ATRA; all-t
Keywords: PTP1B; protein tyrosine phosphatase 1B; CNS; central nervous system; HFD; high fat diet; NPY; neuropeptide Y; AMPK; 5' AMP-activated protein kinase; BAT; brown adipose tissue; AF; albiflorin; hAMSCs; human adipose tissue-derived mesenchymal stem cells; PP
Keywords: AA; Antimycin A; ADFI; average daily feed intake; ADG; average daily gain; AMPK; AMP-activated protein kinase; ATP; adenosine triphosphate; CAT; catalase; CR; caloric restriction; CS; citrate synthase; cyt b; cytochrome b; ESRRA; estrogen-related receptor
Keywords: AN; adult neurogenesis; AHR; aryl hydrocarbon receptor; APC; adenomatous polyposis coli; ARE; antioxidant responsive element; Axin; tumor suppressors Axin; aNSCs; adult neural stem cells; BMSCs; bone marrow-derived mesenchymal stem cells; BMPs; bone morph
Keywords: ACS; Acyl-CoA synthetase; ARE/EpRE; Antioxidant/electrophile response element; Bcl-2; B-cell lymphoma 2; BMI; Body mass index; BSP; Broccoli sprout powder; CAT; Catalase; C/EBP; CCAAT/enhancer-binding protein; CD36; CD36 molecule/thrombospondin receptor;
Keywords: Mechanotransduction; Nitric oxide; Sheddases; Sirtuin 1; Diabetes;
Keywords: Strawberry; LPS; Human Dermal Fibroblast; Inflammation; Oxidative stress; Antioxidant response; Prevention; 2-DG; 2-deoxyglucose; 2,4 DNP; 2,4-Dinitrophenol; ABB; annexin binding buffer; ABTS; 2,20-azino-bis-(3-ethylbenzothiazoline-6-sulfonic acid) diammo
Keywords: Flavonoids; Quercetin; Plant-derived polyphenol; Cardiovascular action; Bioassay; CVD; Cardiovascular disease; eNOS; endothelial nitric oxide synthase; BcL2; B-cell lymphoma 2; MDA; malonaldehyde; TNFα; tumor necrosis factor α; IL-6; Interleukin 6; PPAR
Keywords: AD; Alzheimer's Disease; HADACs; histone deacetylases; APP; amyloid precursor protein; SIRT1; sirtuin 1; APOE; apolipoprotein E; PSEN1; presenilin 1; PIN1; peptidyl prolyl isomerase 1; PBMCs; peripheral blood mononuclear cells; DNMTs; DNA methyltransfer
Keywords: Sirt1; Sirtuin 1; SREBPs; Sterol regulatory element binding proteins; AMPK; AMP-activated protein kinase; ACC; Acetyl-CoA carboxylase; Fas; Fatty acid synthase; Nampt; Nicotinamide phosphoribosyltransferase; LKB1; Liver kinase B1; ER; Endoplasmic reticulu
Keywords: Quercetin; Hepatoprotection; Heme oxygenase 1; Sirtuin 1; Carbon tetrachloride; Hepatotoxicity;
Keywords: ACADL; acyl-coenzyme A dehydrogenase long-chain; ACSL3; acyl-CoA synthetase long-chain family member 3; BAX; BCL2-associated X; BCL2; B-cell lymphoma 2; BSA; bovine serum albumin; CDS FBS; charcoal:dextran stripped fetal bovine serum; COC; cumulus-oocyte
Dietary tea polyphenols ameliorate metabolic syndrome and memory impairment via circadian clock related mechanisms
Keywords: TP; tea polyphenols; DD; constant darkness; SCN; suprachiasmatic nucleus; LD; light-dark; CLOCK; circadian locomotor output cycles kaput; BMAL1; brain and muscle arnt-like protein-1; CRY; cryptochromes; REV-ERB; -; RORs; RAR-related orphan receptors; PE
Keywords: CAT; catalase; CVD; cardiovascular disease; EC; endothelial cells; Egt; ergothioneine, 2-mercaptohistidine betaine; EH; hercynine; EIC; extracted ion chromatogram; eNOS; endothelial nitric oxide synthase; ESH; 2-mercaptohistidine betaine, ergothioneine; E
Keywords: AD; Alzheimer's disease; ADF; alternate day fasting; ALS; amyotrophic lateral sclerosis; APP; β-amyloid precursor protein; BDNF; brain-derived neurotrophic factor; CER; continuous energy restriction; CR; caloric restriction; CREB; cyclic AMP response e
Keywords: berberine; non-alcoholic fatty liver disease; oxidative stress; sirtuin 1; uncoupling protein 2;
Keywords: Atopic dermatitis; filaggrin; biologics; cytokines; chemokines; thymic stromal lymphopoietin; chemoattractant receptor-homologous molecule expressed on TH2 cells; petrolatum; ultraviolet B; sirtuin 1; aryl hydrocarbon receptor; Janus kinase; signal transd
Keywords: Sirt1; Sirtuin 1; DMN; dimethylnitrosamine; HO-1; Heme oxygenase -1; GST; glutathione-S-transferase; GCLC; glutathione cysteine ligase catalytic subunit; GCLM; glutathione cysteine ligase modifier subunit; Nrf2; NF-E2-related factor 2; ALT; alanine aminot
Keywords: RSV; resveratrol (3,5,4â²-trihydroxy-trans-stilbene); SIRT1; sirtuin 1; PDE4; phosphodiesterase 4; ROS; reactive oxygen species; HNE; 4-hydroxy-2-nonenal; GSH; glutathione; KBM; keratinocyte basal medium; KGM; keratinocyte growth medium; NHEK; neonatal n
Keywords: ACC; acetyl CoA carboxylase; ALT; alanine aminotransferase; AMPK; 5' adenosine monophosphate-activated protein kinase; AST; aspartate transaminase; CRP; C-reactive protein; FAS; fatty acid synthase; HFD; high-fat diet; HMB; β-hydroxy-β-methyl-butyrate
Keywords: GnRH neurons; Kisspeptin neurons; Female puberty; Chromatin modifications; DNA methylation; Transcriptional repression; Transcriptional activation; Epigenetic regulators; microRNAs; Long noncoding RNAs; 5hmC; 5-hydroxymethylcytosine; 5-mC; 5-methylcytosin
Keywords: AID/APOBEC; activation-induced cytidine deaminase/apolipoprotein B mRNA-editing enzyme complex; BDNF; brain-derived neurotrophic factor; 5caC; 5-carboxylcytosine; CBP; CREB binding protein; CREB; cAMP response binding protein; DNMT; DNA methyltransferases
Keywords: Abl; Abelson murine leukemia viral oncogene homolog 1; Akt/PKB; protein kinase B; bZIP; basic leucine zipper; C/EBP-β; CCAAT-enhancer-binding protein β; Egr; early growth response; ER; estrogen receptor; Fox; Forkhead box protein; hGH; human growth horm
Keywords: 6-OHDA; 6-hydroxydopamine; AMPK; AMP activated protein kinase; cAMP; cyclic adenosine monophosphate; CAT; catalase; CI; complex I; CII; complex II; CIV; complex IV; COX; cytochrome c oxidase; DMSO; dimethyl sulfoxide; DNP; dinitrophenol; DCF; dichlorodihy
Keywords: AA; arachidonic acid; ADP; adenosine diphosphate; AIF; apoptosis-inducing factor; AMPK; AMP-activated protein kinase; ANT; adenine nucleotide translocase; Apaf-1; apoptotic protease activating factor-1; ATP; adenosine triphosphate; ATP-ase; ATP synthase;
Keywords: AKT/PKB; protein kinase B; Apaf-1; apoptotic protease activating factor 1; ERK; extracellular signal-regulated kinase; ETC; electron transport chain; FADD; Fas-associated death domain; FOXO3a; forkhead-box protein O3a; HK; hexokinase; HNE-1; Na+/H+ exchan
Keywords: ACTB; actin, beta; ACOX1; acyl-CoA oxidase 1; ADCYAP1R1; adenylate cyclase activating polypeptide 1 receptor 1; ADIPOQ; adiponectin C1Q and collagen domain containing; ADIPOR1; adiponectin receptor 1; ADIPOR2; adiponectin receptor 2; ADRA2B; adrenergic re
Keywords: ACC; acetyl-CoA carboxylase; Ahcy; adenosylhomocysteinase; AT; adipose tissue; ATGL; adipose triglyceride lipase; AMPK; AMP-activated protein kinase; Bhmt; betaine-homocysteine S-methyltransferase; CR; caloric restriction; CBS; cystathionine β-synthase;
Keywords: AMPK; 5â²-adenosine monophosphate (AMP)-activated protein kinase; CC; Compound C; DAPI; 4â²,6-diamidino-2-phenylindole; DRG; dorsal root ganglia; E; embryonic day; GSH; glutathione; GSK3β; glycogen synthase kinase 3β; LKB1; serine/threonine kinase 11;
Loss of NRF-2 and PGC-1α genes leads to retinal pigment epithelium damage resembling dry age-related macular degeneration
Keywords: ER; endoplasmic reticulum; AMD; age-related macular degeneration; RPE; retinal pigment epithelium; PUFAs; polyunsaturated fatty acids; ROS; reactive oxygen species; NRF-2; nuclear factor-erythroid 2-related factor-2; ARE; antioxidant response element; Kea
MicroRNA-204-5p regulates 3T3-L1 preadipocyte proliferation, apoptosis and differentiation
Keywords: C/EBPα; CCAAT/enhancer-binding proteins; PPAR-γ; peroxisome proliferator activated receptor-γ coactivator; AP2; adipocyte fatty-acid binding protein 2; CDK4; cyclin dependent kinase 4; CDK2; cyclin dependent kinase 2; CDK5; cyclin dependent kinase 5; p
Reduced gene expression of sirtuins and active AMPK levels in children and adolescents with obesity and insulin resistance
Keywords: Sirtuin 1; Sirtuin 2; AMP-activated protein kinase; Obesity; Children;
d-galactose induces premature senescence of lens epithelial cells by disturbing autophagy flux and mitochondrial functions
Keywords: d-gal; d-galactose; LECs; lens epithelial cells; HCQ; hydroxychloroquine; ROS; reactive oxygen species; VADC; voltage dependent anion channel; mPTP; mitochondria permeability transition pore; MMP; mitochondrial membrane potential; NAC; N-acetylcysteine; G
The reciprocal link between EVI1 and miRNAs in human malignancies
Keywords: EVI1; ecotropic virus integration site-1; MiR; microRNA; 3â²-UTR; 3â²-untranslated regions; AML; acute myeloid leukemia; DNA; deoxyribonucleic acid; RNA; ribonucleic acid; NF-κβ; nuclear factor kappa β; CHIP; Chromatin Immunoprecipitation; c-Myb; c-m
C1q tumor necrosis factor-related protein 9 in atherosclerosis: Mechanistic insights and therapeutic potential
Keywords: CTRP9; AdipoR1; N-cadherin; Atherosclerosis; Adiponectin; CVD; cardiovascular disease; CTRPs; C1q tumor necrosis factor-related proteins; AMI; acute myocardial infarction; HMW; high molecular weight; AMPK; adenosine monophosphate-activated protein kinase;
Ablation of carotenoid cleavage enzymes (BCO1 and BCO2) induced hepatic steatosis by altering the farnesoid X receptor/miR-34a/sirtuin 1 pathway
Keywords: Fatty liver disease; Carotenoid cleavage enzymes; Farnesoid X receptor; Sirtuin 1;
Impairment of Akt activity by CYP2E1 mediated oxidative stress is involved in chronic ethanol-induced fatty liver
Keywords: AFL; alcoholic fatty liver; ALD; alcoholic liver disease; ALT; alanine transaminase; AMPK; AMP-activated protein kinase; AST; aspartate transaminase; CMZ; chlormethiazole; CYP2E1; cytochrome P4502E1; 4-HNE; 4-hydroxynonenal; IGF-1; insulin-like growth fac
Exercise intervention attenuates hyperhomocysteinemia-induced aortic endothelial oxidative injury by regulating SIRT1 through mitigating NADPH oxidase/LOX-1 signaling
Keywords: HHcy; hyperhomocysteinemia; Hcy; homocysteine; LOX-1; lectin-like oxidized low density lipoprotein receptor-1; PKC; protein kinase C; SIRT1; sirtuin 1; CAD; coronary artery disease; SOD; superoxidase dismutase; GPx; glutathione peroxidase; and AMPK; AMP-a
Nicotinamide riboside attenuates alcohol induced liver injuries via activation of SirT1/PGC-1α/mitochondrial biosynthesis pathway
Keywords: ADH; alcohol dehydrogenase; ALD; Alcoholic liver disease; ALDH; aldehyde dehydrogenase; CPT-1α; carnitine palmitoyl transterase-1α; CR; calorie restriction; CS; citrate synthase; CYP2E1; cytochrome P450 2E1; FASN; fatty acid synthase; NAD+; nicotinamide
Protection by different classes of dietary polyphenols against palmitic acid-induced steatosis, nitro-oxidative stress and endoplasmic reticulum stress in HepG2 hepatocytes
Keywords: Non-alcoholic fatty liver disease; Functional food polyphenols; Endoplasmic reticulum stress; Oxidative stress; Mitochondrial dysfunction; AMPK; AMP-activated protein kinase; ATP5G1; ATP synthase, mitochondrial Fo complex, subunit C1 (subunit 9); CCCP; ca
Swimming exercise reverses CUMS-induced changes in depression-like behaviors and hippocampal plasticity-related proteins
Keywords: AKT; protein kinase B; BDNF; brain-derived neurotrophic factor; CREB; cAMP response element-binding protein; CUMS; chronic unpredictable mild stress; FST; forced swim test; GAP-43; growth-associated protein-43; GSK-3β; glycogen synthase kinase-3β; OFT;
Long non-coding RNA TUG1 protects renal tubular epithelial cells against injury induced by lipopolysaccharide via regulating microRNA-223
Keywords: Lupus nephritis; Long non-coding RNA taurine upregulated gene 1; MicroRNA-223; Sirtuin 1; Inflammatory injury;
Carnosol-mediated Sirtuin 1 activation inhibits Enhancer of Zeste Homolog 2 to attenuate liver fibrosis
Keywords: carnosol (PubChem CID:442009); resveratrol (PubChem CID:445154); DZNep; 3-Deazaneplanoci A; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CS; carnosol; CCl4; carbon tetrachloride; H3K27me3; catalyzes trimethylation of lysine 27 on histon
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
An in vitro comparative study of the antioxidant activity and SIRT1 modulation of natural compounds
Keywords: AMPK; adenosine monophosphate-activated protein kinase; APAB; 2,2â²-azo-bisamidinopropane; BSA; bovine serum albumin; CCL4; carbon tetrachloride; DMEM; Dulbecco's modified eagle's medium; DMSO; dimethyl sulfoxide; DTPA; diethylenetriaminepentaacetic acid
Tanshindiol C inhibits oxidized low-density lipoprotein induced macrophage foam cell formation via a peroxiredoxin 1 dependent pathway
Keywords: Tan C; Tanshindiol C; oxLDL; oxidized low-density lipoprotein; Nrf2; NF-E2-related factor 2; ARE; antioxidant-response element; Sirt1; Sirtuin 1; Prdx1; peroxiredoxin 1; ABCA1; adenosine triphosphate-binding cassette (ABC) transporter A1; ABCG1; ATP-bindi
The ADRA2A rs553668 variant is associated with type 2 diabetes and five variants were associated at nominal significance levels in a population-based case-control study from Mexico City
Keywords: ADRA2A; Alpha-2a-adrenergic receptor; BMI; Body mass index; CHO; Cholesterol; DNA; Deoxyribonucleic acid; ENSANUT; National Survey of Health and Nutrition; FPG; Fasting plasma glucose; GWAS; Genome wide association study; HDL-C; Cholesterol high density l
MicroRNAs in the pathogenesis and treatment of progressive liver injury in NAFLD and liver fibrosis
Keywords: ApoB; apolipoprotein B; CBDL; common bile duct ligation; CCl4; carbon tetrachloride; CPT1; peroxisome carnitine palmitoyl transferase 1; CREBH; cAMP responsive element binding protein H; DNL; de novo lipogenesis; ECM; extracellular matrix; ER; endoplasmic
Erythropoietin alleviates hepatic steatosis by activating SIRT1-mediated autophagy
Keywords: Autophagy; Hepatic steatosis; Erythropoietin; Sirtuin 1;