Keywords: Sirtuins; Mood; Metabolic; Depression; Bipolar; Disorder;
مقالات ISI (ترجمه نشده)
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در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Keywords: CVDs; cardiovascular diseases; ECs; endothelial cells; VSMCs; vascular smooth muscle cells; HPTMs; histones post-translational modifications; nt; nucleotides; 5-mC; 5-methylcytosine; 5-hmC; 5-hydroxymethylcytosine; CpG; sequence of cytosine followed by a
Keywords: Sirtuins; Nutrient deprivation; Calorie restriction; Epigenetics; Chromatin; Gene expression;
Keywords: Yeast aging; Replicative lifespan (RLS); Dietary restriction (DR); Target of rapamycin (TOR); Sirtuins; Mitochondria; Reactive oxygen species (ROS); Retrograde response; Ribosomal DNA (rDNA); Ubiquitin/proteasome system (UPS); Proteostasis; Cell asymmetry
Keywords: ADA2; Adenosine deaminase 2; ASH1L; Absent, Small, or Homeotic 1-like; BAF; BRG1 associated factor; BAH; Bromoadjacent homology; BAZ2A; Bromodomain adjacent to zinc finger domain protein 2A; BET; Bromodomain and Extra-Terminal domain; BRPF1; Bromodomain a
Keywords: Ageing; Neurodegeneration; Polyphenolic; SIRT1â; Sirtuins;
Keywords: 20-HETE; 20-hydroxyeicosatetraenoic acid; ACE; angiotensin converting enzyme; ACEI; angiotensin converting enzyme inhibitor; Agt; angiotensinogen; Agt â/â; Â Agt whole body knock-out mouse model; AMPK; AMP-activated protein kinase; Ang II; angiotensin
Keywords: Acetylcholinesterase; Alzheimer's disease; Caspases; Lipoxygenase; Sirtuins;
Keywords: Yeast; Worms; Flies; Mitochondrial respiration; Sirtuins; Autophagy; Metabolism;
Keywords: Mesenchymal stem cells; Epigenetics; Metabolism; Cardiovascular diseases; Cardiac fibroblast; Regenerative medicine; bFGF; basic fibroblast growth factor; BM; bone marrow; BM-MSCs; bone marrow-derived mesenchymal stem cells; CMSCs; cardiac mesenchymal ste
Keywords: Mitochondria; Heart failure; Cardiolipin; Sirtuins; Resveratrol; Reactive oxygen species;
Keywords: AMPK; AMP-activated protein kinase; BM; bone marrow; CAT; catalase; Complex I; NADH-coenzyme Q oxidoreductase; Complex II; succinate-coenzyme Q oxidoreductase; Complex III; ubiquinol-cytochrome c oxidoreductase; COX; cytochrome c oxidase; Complex V; FoF1A
Keywords: Longevity; Aging; Maillard reaction; Sirtuins; SupercentenariansLongévité; Vieillissement; Réaction de Maillard; Sirtuines; Supercentenaires
Keywords: Neurodegeneration; Preconditioning; Stress responses; Chromatin remodeling; Post-transcriptional; DNA methylation; Sirtuins; Heat shock factor-1; RE-1 silencing transcription factor;
Keywords: CAC; citric acid cycle; ROS; reactive oxygen species; SIRT; sirtuin; STACs; sirtuin-activating compounds; Aerobic glycolysis; Cancer; Epigenetics; Sirtuins; The Warburg effect;
Keywords: Mitochondria; Atherosclerosis; Neurodegeneration; Stem cells; Osteoporosis; Sirtuins; Immunity; Aging;
Keywords: Sirtuins; Diabetic cardiomyopathy; Resveratrol; Acetylation; T1DM; T2DM;
Keywords: Sirtuins; Cancer metabolism; NAD deacylases; Aging;
Keywords: Intermittent fasting diet; Glucose; AMPK; mTOR; Sirtuins; Autophagy;
Keywords: Exercise; Brain cortex; Neuroprotection; Middle age; Amyloid beta; Sirtuins;
Keywords: Mitochondria; Mitochondrial diseases; Neurodegenerative disorders; Pharmacological neuroprotection; Mitochondrie; Maladies mitochondriales; Maladies neurodégénératives; Neuroprotection pharmacologique; AD; Alzheimer's disease; AICAR; 5-aminoimidazole-4
Keywords: Resveratrol; Cardioprotection; Red wine; Grapes; Polyphenolic; SIRT1; Sirtuins; Stilbene; Polygonum cuspidatum; Longevity; Caloric restriction; Cardiovascular health
Keywords: Aβ; amyloid beta; AD; Alzheimer's disease; AICD; APP intracellular domain; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APP; amyloid β precursor protein; Apo E; apolipoprotein E; BACE1; β-site APP converting enzyme 1; BDNF; brain derive
Keywords: Aging; Caloric restriction; Sarcopenia; Apoptosis; Biogenesis; Sirtuins;
Keywords: Parkinson's disease; Huntington's disease; Neurodegenerative diseases; Mitochondrial dysfunction; Creatine; Co-Q10; PGC-1α; Sirtuins;
Keywords: PD; Parkinson's disease; AD; Alzheimer's disease; HD; Huntington's Disease; ALS; Amyotrophic Lateral Sclerosis; TAR DNA; binding protein TDP-43; TCA; tricarboxylic acid cycle; ROS; reactive oxygen species; MPTP; 1-methyl-4-phenyl-1,2,3,6-tetrahydrod
Keywords: Arterial aging; Endothelial dysfunction; Nitric oxide; Oxidative stress; Reactive oxygen species; Inflammation; Nuclear factor-κB; Sirtuins;
SIRT3-mediated cardiac remodeling/repair following myocardial infarction
Keywords: MI; myocardial infarction; HIF; hypoxia inducible factor-1α; SOD2; superoxide dismutase; FOXO3A; forkhead box O3a; OPA1; optic atrophy 1; MMPs; matrix metalloproteinases; TGF-β; transforming growth factor-β; PARP-1; poly (ADP ribose)- polymerase 1; VEG
Tissue distribution, subcellular localization, and enzymatic activity analysis of human SIRT5 isoforms
Keywords: Sirtuins; SIRT5; Protein isoform; Acylase; Malonylation; Succinylation; Acetylation;
A pilot study of the modulation of sirtuins on arylamine N-acetyltransferase 1 and 2 enzymatic activity
Keywords: Ac-INH; acetyl-Isoniazid; Ac-PABA; acetyl-p-aminobenzoic acid; APC; allophycocyanin; CHO; Chinese hamster ovary cells; DMEM; Dulbecco's modified Eagle's medium; E2F1; E2F transctriptios factor 1; ER81; ETS-related protein 81; FITC; fluorescein IsoTioCyana
Targeting NAD+ degradation: The therapeutic potential of flavonoids for Alzheimer's disease and cognitive frailty
Keywords: Flavonoids; NAD+; PARP-1; CD38; Sirtuins; Alzheimer's disease; Cognitive frailty;
Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration
Keywords: IVD; intervertebral disc; NP; nucleus pulposus; SIRTs; Sirtuins; AGEs; advanced glycation end products; NMN; nicotinamide mononucleotide; SKQ1; Visomitin; MitoTEMPO; (2-(2,2,6,6-Tetramethylpiperidin-1-oxyl-4-ylamino)-2-oxoethyl) triphenylphosphonium chlor
Role of Sirtuin1-p53 regulatory axis in aging, cancer and cellular reprogramming
Keywords: Sirtuins; Localisation of sirtuins; Senescence; Cellular energy metabolism; Inflammation; Tumour suppressor; Tumour promoter; Pluripotency;
Sirtuin 1 and Alzheimer's disease: An up-to-date review
Keywords: Sirtuins; SIRT1; Alzheimer's disease; Cognition; Neurodegeneration;
Deficiency of the Mitochondrial NAD Kinase Causes Stress-Induced Hepatic Steatosis in Mice
Keywords: CREBH; PPARα; Liver Injury; Mouse Model; Steatohepatitis; AHF; atherogenic high-fat; ALT; alanine aminotransferase; AST; aspartate aminotransferase; CREBH; hepatocyte-specific cAMP-responsive element binding protein; DECR; 2,4 dienoyl-coA reductase; FAO;
Nuclear sirtuins and inflammatory signaling pathways
Keywords: Inflammation; Sirtuins; Sirtuin 1; Sirtuin 2; NF-kappa β;
Design, synthesis and anticancer activity of N-(1-(4-(dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl)-1-oxo-3-phenylpropan-2-yl derivatives
Keywords: Dibenzo[b,f][1,4]thiazepin; Synthesis; Anticancer activity; Sirtuins; Sunitinib;
Metabolic control by sirtuins and other enzymes that sense NAD+, NADH, or their ratio
Keywords: Sirtuins; Nicotinamide adenine dinucleotide; Metabolism; Mitochondria; Redox;
Sirtuins, epigenetics and longevity
Keywords: Sirtuins; Epigenetics; Longevity; Aging; DNA;
Intestinal SIRT3 overexpression in mice improves whole body glucose homeostasis independent of body weight
Keywords: Insulin resistance; Oxidative metabolism; Ketone bodies; Enterocytes; Gut; Sirtuins;
Synthesis of highly substituted 3-arylideneindolin-2-ones
Keywords: Sirtuins; Indolin-2-ones; Oxindoles; 3-Arylideneindolin-2-ones; Cross-coupling;
NAD and the aging process: Role in life, death and everything in between
Keywords: CD38; PARP; SIRTUINS; NAD+; Mitochondrial function; Aging;
The plasticizer BBP selectively inhibits epigenetic regulator sirtuin during differentiation of C3H10T1/2 stem cell line
Keywords: BBP; Benzyl butyl phthalate; PGC1α; Peroxisome proliferator-activated receptor gamma coactivator 1 alpha; NRF1; Nuclear respiratory factor 1; NRF2; Nuclear respiratory factor 2; Tfam; Mitochondrial transcription factor A; FOXO1; Forkhead box protein O1;
Caloric restriction alleviates alpha-synuclein toxicity in aged yeast cells by controlling the opposite roles of Tor1 and Sir2 on autophagy
Keywords: CLS; chronological lifespan; CR; caloric restriction; CFUs; counting colony-forming units; NCR; non caloric restriction; syn; α-synuclein; Caloric restriction; Autophagy; Sirtuins; Alpha-synuclein; Synucleinopathies;
Sirtuins in metabolism, stemness and differentiation
Keywords: Stem cells; Pluripotency; Differentiation; Metabolism; Sirtuins; SIRT1;
Discovery of 2-((4,6-dimethylpyrimidin-2-yl)thio)-N-phenylacetamide derivatives as new potent and selective human sirtuin 2 inhibitors
Keywords: Sirtuins; SIRT2; Epigenetics; Cancer; Structure-based optimization; OWBSTMIZVSYGTH-UHFFFAOYSA-N;
Adipose tissue NAD+-homeostasis, sirtuins and poly(ADP-ribose) polymerases -important players in mitochondrial metabolism and metabolic health
Keywords: Obesity; Mitochondria; Adipose tissue; Sirtuins; Poly(ADP-ribose) polymerases; NAD+;
SIRT1 and insulin resistance
Keywords: Sirtuins; Type 2 diabetes mellitus; Insulin resistance; Organ; Tissue;
5-Benzylidene-hydantoin is a new scaffold for SIRT inhibition: From virtual screening to activity assays
Keywords: Sirtuins; 5-Benzylidene-hydantoin; Virtual screening; Molecular dynamics; Enzymology; PAMPA; p53 acetylation; ADP; Adenosine ribose diphosphate; ADME; Absorption distribution metabolism excretion; BBB; Blood-brain barrier; CNS; Central nervous system; G