Keywords: ACTB; actin beta; ALAS1; aminoerulinate, delta-synthase 1; B2M; beta-2-microglobulin; DMEM; Dulbecco's modified Eagle's medium; DMOG; dimethyloxalylglycine; DSCR1; Down syndrome critical region gene 1; FBS; fetal bovine serum; G6PD; glucose-6-phophate deh
مقالات ISI (ترجمه نشده)
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Keywords: AGO; Argonaute; ARG1; arginase1; ATM; adipose tissue macrophage; BAT; brown adipose tissue; BMDM; bone marrow derived macrophage; C/EBP; CCAAT-enhancer-binding proteins; CCL2; C-C Motif Chemokine Ligand 2; CCR2; C-C Motif Chemokine Receptor 2; CLS; crown-
Keywords: SOCS1; NSCs; Proliferation; Differentiation;
Keywords: Systemic lupus erythematosus; Lupus nephritis; Podocytes; Lupus mice model; Immunosuppressive drugs; CD2AP; CD2-associated protein; TRPC; transient receptor potential canonical; IL; interleukin; TNFα; tumoral necrosis factor-alpha; IFNγ; interferon-gamm
Keywords: APCs; antigen presenting cells; ATP; adenosine triphosphate; BBB; blood brain barrier; BM; bone marrow; CB; cord blood; CNS; central nervous system; CSF; cerebrospinal fluid; DAMPs; danger associated molecular pattern molecules; DCs; dendritic cells; EAE;
Keywords: Polyphenols; Antibiotics; Antioxidants; PACAP; Aβ; β-amyloid; AD; Alzheimer's disease; AMPK; AMP-activated protein kinase; BBB; blood-brain barrier; BDNF; brain-derived neurotrophic factor; CAT; catalase; CNS; central nervous system; COX-2; cyclooxyge
Keywords: Liver fibrosis; SOCS1; Dimethylnitrosamine; Carbon tetrachloride; Hepatic stellate cells; PDGFALT, alanine transferase; CCl4, carbon tetrachloride; DMN, dimethylnitrosamine; ECM, extra-cellular matrix; GBSS, Gey’s Balanced Salt Solution; HCC, hepatocellul
Keywords: AP-1; jun proto-oncogene; BAI3; brain-specific angiogenesis inhibitor 3; CADM2; cell adhesion molecule 2; CAGE; cap analysis of gene expression; cDNA; DNA complementary to RNA; ChIP; chromatin immunoprecipitation; FGF14; fibroblast growth factor 14; GADD4
Keywords: Colorectal cancer; SOCS1; Invasion; Metastasis;
Keywords: ABCA; ATP-binding cassette transporter; AIM; Apoptosis inhibitor of macrophage; APC; antigen-presenting cell; ASC; apoptotic speck protein containing a caspase recruitment domain; AT; adipose tissue; ATM; AT macrophage; BLT; leukotriene B4 receptor; BM; b
Keywords: AHR; aryl hydrocarbon receptor; AIP; aryl hydrocarbon receptor interacting protein; BMP-4; bone morphogenetic protein 4; CDK; cyclin-dependent kinases; CDKN1A; cyclin-dependent kinase inhibitor 1A; CDKN1B; cyclin-dependent kinase inhibitor 1B; CDKN2A; cyc
Keywords: SOCS1; SOCS3; chronic rhinosinusitis with nasal polyps; chronic rhinosinusitis without nasal polyps; cytokines; CRS; Chronic rhinosinusitis; CRSsNP; CRS without nasal polyps; CRSwNP; CRS with nasal polyps; CT; Computed tomography; SOCS; Suppressor of cyto
Keywords: BDL; bile duct ligated; DFA; detrended fluctuation analysis; HRV; heart rate variability; IL-6; interleukin 6; LPS; lipopolysaccharide; SHAM; sham-operated; SOCS1; suppressor of cytokine signaling-1; TGF-β; transforming growth factor-beta; Cirrhosis; End
Effects of guluronic acid (G2013) on SHIP1, SOCS1 induction and related molecules in TLR4 signaling pathway
Keywords: G2013; Guluronic acid; SHIP1; SOCS1; TLR4; MyD88;
Josamycin suppresses Prevotella intermedia lipopolysaccharide-induced production of nitric oxide and interleukin-1β in murine macrophages
Keywords: josamycin; nitric oxide; interleukin-1β; HO-1; NF-κB; SOCS1;
Necroptosis in 3-chloro-1, 2-propanediol (3-MCPD)-dipalmitate-induced acute kidney injury in vivo and its repression by miR-223-3p
Keywords: 3-MCPD; 3-chloro-1,2-propanediol; 3â²UTR; 3â² un-translated region; AKI; acute kidney injury; BMD10; Benchmark doses; BMDL10; BMD Lower Confidence Limit; BW; body weight; CXCl; chemokine (C-X-C motif) ligand; DE; differentially expressed; DR6; death rec
Association between Type I interferon and depletion and dysfunction of endothelial progenitor cells in C57BL/6 mice deficient in both apolipoprotein E and Fas ligand
Keywords: SLE; systemic lupus erythematosus; EPCs; endothelial progenitor cells; IFN-I; type I interferon; FACS; fluorescence-activated cell sorting; FITC-UEA-1; fluorescein isothiocyanate labeled Ulex europaeus agglutinin 1; DII-ac-LDL; 3â²-tetramethylindocarbocy
Identifying causal variants at the interferon lambda locus in case-control studies: Utilizing non-synonymous variant rs117648444 to probe the role of IFN-λ4
Keywords: IFNL or IFN-λ; interferon lambda; GWAS; genome-wide association studies; IFN-RBV; interferon-α-ribavirin; LD; linkage disequilibrium; HCV; Hepatitis c virus; SNP; Single nucleotide polymorphism; ISGs; interferon-stimulated-genes; UTR; untranslated regio
Osteoglycin post-transcriptional regulation by miR-155 induces cellular architecture changes in H9c2 cardiomyoblasts
Keywords: miRNAs; microRNAs; Ogn; osteoglycin/mimecan; 3â²UTR; 3â² untranslated region; HF; heart failure; Socs1; suppressor of cytokine signaling 1; FoxO3a; Forkhead box O3a; ECM; extracellular matrix; GM; growth medium; RIN; RNA integrity number; PBS; Phosphate
The role of lnc-DC long non-coding RNA and SOCS1 in the regulation of STAT3 in coronary artery disease and type 2 diabetes mellitus
Keywords: Coronary artery disease; Inflammation; STAT3; Type2 diabetes mellitus; lnc-DC; SOCS1;
MicroRNA-155 induces autophagy in osteoclasts by targeting transforming growth factor β-activated kinase 1-binding protein 2 upon lipopolysaccharide stimulation
Keywords: BMM; bone marrow-derived macrophages; M-CSF; macrophage-colony stimulating factor; miR; microRNA; miR-155; microRNA-155; MNC; multinucleated cells; OC; osteoclast; PBS; phosphate-buffered saline; qPCR; quantitative polymerase chain reaction; RANKL; recept
Sustained anti-inflammatory effects of TGF-β1 on microglia/macrophages
Keywords: bFGF; basic fibroblast growth factor; Contra; contralateral cortex; DAMPs; damage-associated molecular patterns; dpr; days post-reperfusion; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; HGF; hepatocyte growth factor; HMGB1; high mobility group box 1;
Atlantic salmon post-smolts adapted for a longer time to seawater develop an effective humoral and cellular immune response against Salmonid alphavirus
Keywords: Salmo salar; Bath immersion; Adaptive response; Smoltification; Pancreas disease; Immunoglobulin; B cells; RIG-1; SOCS1; CD40; Interleukin;
Reduced frequency of murine cytomegalovirus retinitis in C57BL/6 mice correlates with low levels of suppressor of cytokine signaling (SOCS)1 and SOCS3 expression within the eye during corticosteroid-induced immunosuppression
Keywords: AIDS-related cytomegalovirus retinitis; Murine cytomegalovirus; MAIDS; Corticosteroids; Suppressors of cytokine signaling (SOCS); SOCS1; SOCS3;
Acitretin modulates HaCaT cells proliferation through STAT1- and STAT3-dependent signaling
Keywords: Acitretin; HaCaT cells; STAT1; STAT3; SOCS1; SOCS3;
SOCS gene family expression profile in the blood of multiple sclerosis patients
Keywords: Multiple sclerosis; SOCS1; SOCS2; SOCS3; SOCS5; Expression; Real Time PCR;
Research paperDendritic cells that highly express SOCS1 induce T-cell hypo-responsiveness and prolong islet allograft survival
Keywords: Dendritic cell; Immune tolerance; Islet transplant; SOCS1; T-cell hypo-responsiveness;
Effect of nitric oxide-releasing derivative of indomethacin on Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages
Keywords: NCX 2121; Lipopolysaccharide; Proinflammatory mediators; HO-1; NF-κB; SOCS1;
Targeting androgen receptor with ASC-J9 attenuates cardiac injury and dysfunction in experimental autoimmune myocarditis by reducing M1-like macrophage
Keywords: Androgen receptor; Experimental autoimmune myocarditis; Macrophage; SOCS1; STAT5;
Pregnenolone 16α-carbonitrile ameliorates concanavalin A-induced liver injury in mice independent of the nuclear receptor PXR activation
Keywords: PXR; pregnane X receptor; PCN; pregnenolone 16α-carbonitrile; Con A; concanavalin A; DSS; dextran sulfate sodium; TNF; tumor necrosis factor; LPS; lipopolysaccharide; NF-κB; nuclear factor κB; MPO; myeloperoxidase; SOCS1; suppressor of cytokine signali
THP-1 and human peripheral blood mononuclear cell-derived macrophages differ in their capacity to polarize in vitro
Keywords: ACTB; β-actin; CCL2; chemokine (C-C motif) ligand 2; CCL18; chemokine (C-C motif) ligand 18; CCL22; chemokine (C-C motif) ligand 22; CCR7; chemokine (C-C motif) receptor 7; CD; cluster of differentiation; COX2; cytochrome C oxidase-2; IFNγ; interferon-Î
The role of interleukin-17A in the pathogenesis of kidney diseases
Keywords: Interleukin-17A; inflammation; kidney disease; AHR; aryl hydrocarbon receptor; AKI; acute kidney injury; ANCA; antineutrophil cytoplasmic antibody; APOE; apolipoprotein E; ASC; apoptosis-associated speck-like protein containing a carboxy-terminal CARD; Ct
Understanding the role of SOCS signaling in neurodegenerative diseases: Current and emerging concepts
Keywords: SOCS1; SOCS3; Cytokines; Neuroinflammation; Signaling; Immunity;
Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
Keywords: ANOVA; analysis of variance; AA; arachidonic acid; BUN; blood urea nitrogen; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IRAK1; interleukin-1 receptor-associated kinase 1; LPS; lipopolysaccharide; LPS-EB; LPS from E. coli O111: B4
Effect of SOCS1 overexpression on RPE cell activation by proinflammatory cytokines
Keywords: RPE; SOCS1; UVEITIS; IFNγ; ,IL-17; IL-8;
Sponges against miR-19 and miR-155 reactivate the p53-Socs1 axis in hematopoietic cancers
Keywords: SOCS1; p53; miR-19; miR-155; miRNA sponges; Catalytic sponges
Research reportSOCS1 regulates neuropathic pain by inhibiting neuronal sensitization and glial activation in mouse spinal cord
Keywords: SOCS1; Spinal cord; Neuropathic pain; Neuron; Glia; Inflammation;
SOCS1 in cancer: An oncogene and a tumor suppressor
Keywords: SOCS1; Cytokine; Cancer; Tumor suppressor; Oncogene; Colorectal cancer
MicroRNAs: New regulators of IL-22
Keywords: IL-22; interleukin-22; Th22; T helper 22 cell; Th1; T helper 1 cell; Th17; T helper 17 cell; NK22; natural killer 22; NKT; natural killer T cell; ILCs; innate lymphoid cells; RORγt; retinoid orphan receptor γt; STAT3; signal transducer and activator of
Altered signaling in systemic juvenile idiopathic arthritis monocytes
Keywords: Juvenile arthritis; Monocytes; IFN signaling; SOCS1;
Increased 5-hydroxymethylcytosine in CD4+ T cells in systemic lupus erythematosus
Keywords: Systemic lupus erythematosus; Epigenetics; CD4+ T cells; Hydroxymethylation; Methylation; SOCS1; CTCF
The suppressor of cytokine signaling SOCS1 promotes apoptosis of intestinal epithelial cells via p53 signaling in Crohn's disease
Keywords: Crohn's disease; SOCS1; Intestinal epithelial cells; Apoptosis; p53
A lipid nanoparticle for the efficient delivery of siRNA to dendritic cells
Keywords: Cancer immunotherapy; siRNA nanoparticle; Dendritic cell; Endosomal escape; SOCS1; Dendritic cell-based vaccine;
Association of SOCS1− 820 (rs33977706) gene polymorphism with chronic periodontitis: A case–control study in Brazilians
Keywords: SOCS1; Chronic periodontitis; Genetic polymorphism
Expression of suppressor of cytokine signaling 1 (SOCS1) gene dramatically increases in relapsing-remitting multiple sclerosis
Keywords: Multiple sclerosis; SOCS1; Genotyping; Gene expression; Cytokine; JAK-STAT;
Topical administration of a suppressor of cytokine signaling-1 (SOCS1) mimetic peptide inhibits ocular inflammation and mitigates ocular pathology during mouse uveitis
Keywords: Uveitis; Experimental autoimmune uveitis (EAU); Suppressor of cytokine signaling; Ocular inflammation; SOCS1; SOCS1 mimetic; BiologicsSOCS, suppressor of cytokine signaling; SOCS1-KIR, the kinase inhibitory region of SOCS1; EAU, experimental autoimmune uv
Research PaperAntiviral effects of Jinxin oral liquid against respiratory syncytial virus infection in the BALB/c mice model
Keywords: Jinxin oral liquid; Respiratory syncytial virus; TLR3; IRF3; SOCS1;
NCX 4040, a nitric oxide-donating aspirin derivative, inhibits Prevotella intermedia lipopolysaccharide-induced production of proinflammatory mediators in murine macrophages
Keywords: NCX 4040; Lipopolysaccharide; Proinflammatory mediators; HO-1; NF-κB; STAT; SOCS1
CXCL12 and ADAM23 hypermethylation are associated with advanced breast cancers
Keywords: ADAM23; disintegrin and metalloprotease domain 23; APC; adenomatous polyposis coli; BC; breast cancer; BRMS1; breast cancer metastasis suppressor 1; CDH1; cadherin 1, type 1; cfDNA; cell-free DNA; CMI; cumulative methylation index; CXCL12; chemokine C-X-C
MicroRNA-mediated mechanism of vitamin D regulation of innate immune response
Keywords: Vitamin D; Inflammation; Macrophage; miR-155; SOCS1; NF-kappaB; IKKβ; Negative feedback loop;