Genetic variations of SOCS1 are associated with chronic hepatitis B virus infection
Keywords: Chronic hepatitis B virus infection; SOCS1; Polymorphism
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Molecular and cellular pharmacologyEffect of azithromycin on Prevotella intermedia lipopolysaccharide-induced production of interleukin-6 in murine macrophages
Keywords: Azithromycin; Lipopolysaccharide; Interleukin-6; NF-κB; STAT; SOCS1;
Polymer nanoparticles for enhanced immune response: Combined delivery of tumor antigen and small interference RNA for immunosuppressive gene to dendritic cells
Keywords: Nanoparticles; Dendritic cells; Antigen delivery; SOCS1; Cancer vaccine;
MiR-221 accentuates IFN׳s anti-HCV effect by downregulating SOCS1 and SOCS3
Keywords: HCV; Mir-221; SOCS1; SOCS3; IFN-α;
SOCS1 Prevents Graft Arteriosclerosis by Preserving Endothelial Cell Function
Keywords: endothelial activation; endothelial adhesion molecule; SOCS1; EC; endothelial cell; GA; graft arteriosclerosis; ICAM; intercellular adhesion molecule; JAK; Janus kinase; PECAM; platelet/endothelial cell adhesion molecule; SOCS1; suppressor of cytokine sig
Augmented miR-150 expression associated with depressed SOCS1 expression involved in dengue haemorrhagic fever
Keywords: DHF; SOCS1; microRNA; Th1/Th2 cytokine;
Sphingosine 1-phosphate induced anti-atherogenic and atheroprotective M2 macrophage polarization through IL-4
Keywords: S1P; sphingosine 1-phosphate; GPCR; G-protein-coupled receptor; S1P1; sphingosine 1-phosphate receptor type 1 (EDG1); LPS; lipopolysaccharide; iNOS; inducible nitric oxide synthase; COX-2; cyclooxygenase 2; NF-κB; nuclear factor kappa B; STAT6; signal tr
Altered miRNA expression is associated with neuronal fate in G93A-SOD1 ependymal stem progenitor cells
Keywords: ALS; amyotrophic lateral sclerosis; Ccnd2; cyclin D2; Dlx2; distal-less homeobox 2; epSPCs; ependymal stem/progenitor cells; FALS; familial ALS; GAD 67; glutamic acid decarboxylase 67; GFAP; glial fibrillary acidic protein; Hes1; hairy and enhancer of spl
The epigenetic feedback loop between DNA methylation and microRNAs in fibrotic disease with an emphasis on DNA methyltransferases
Keywords: miRNA; microRNA; DNMTs; DNA methyltransferases; HSC; hepatic stellate cell; IPF; idiopathic pulmonary fibrosis; RASAL; Ras GTPase activating-like protein; SOCS1; cytokine signaling-1 gene; PPARγ; peroxisome proliferator-activated receptor γ; MeCP2; meth
Procyanidin dimer B2-mediated IRAK-M induction negatively regulates TLR4 signaling in macrophages
Keywords: DTT; dithiothreitol; FITC; fluorescein isothiocyanate; IFN; interferon; Iκ-B; inhibitor of κB; IL; interleukin; IRAK; IL-1 receptor-associated kinase; LPS; lipopolysaccharide; MAPK; mitogen-activated protein kinase; MyD88; myeloid differentiation factor
SOCS1 abrogates IFN's antiviral effect on hepatitis C virus replication
Keywords: Hepatitis C virus; SOCS1; Interferon; ISG; JFH1;
Peroxiredoxin V selectively regulates IL-6 production by modulating the Jak2-Stat5 pathway
Keywords: PrdxV; peroxiredoxin V; LPS; lipopolysaccaride; IL-6; interleukin 6; Jak2; janus kinase 2; Stat5; signal transducer and activator of transcription 5; SOCS1; suppressor of cytokine signaling 1; TNF-α; tumor necrosis factor α; IFN-β; interferon β; RANTE
IL-27 suppresses the production of IL-22 in human CD4+ T cells by inducing the expression of SOCS1
Keywords: Interleukin-27; Interleukin-22; SOCS1; CD4+ T cells
Loss of Protein Tyrosine Phosphatase Nonreceptor Type 22 Regulates Interferon-γ-Induced Signaling in Human Monocytes
Keywords: SOCS1; ICAM1; MCP1; Th17; CD; Crohn's disease; ERK; extracellular signal-regulated kinase; IBD; inflammatory bowel disease; ICAM; intracellular adhesion molecule; IFN-γ; interferon γ; IκB; inhibitor of κB; IL; interleukin; Jak; Janus kinase; JNK; c-
Polyinosinic-polycytidylic acid attenuates hepatic fibrosis in C57BL/6 mice with Schistosoma japonicum infection
Keywords: Poly I:C; polyinosinic-polycytidylic acid; S. japonicum; Schistosoma japonicum; α-SMA; alpha-smooth muscle actin; DC; dendritic cell; ALT; alanine aminotransferase; AST; aspartate aminotransferase; p.i.; post-infection; HSC; hepatic stellate cells; CCl
miR-155 modulates TNF-α-inhibited osteogenic differentiation by targeting SOCS1 expression
Keywords: BMP-2; Osteoblast differentiation; miR-155; SOCS1; SAPK/JNK;
Tumour-derived IL-10 within tumour microenvironment represses the antitumour immunity of Socs1-silenced and sustained antigen expressing DCs
Keywords: Socs1; DC vaccine; Lentiviral vector; IL-10; Tumour microenvironment;
Reprint of: Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation
Keywords: siRNA; Vaccination; Dendritic cells; SOCS1; Intracellular trafficking
Research ArticleSOCS1 controls liver regeneration by regulating HGF signaling in hepatocytes
Keywords: SOCS1; suppressor of cytokine signaling 1; HCC; hepatocellular carcinoma; HGF; hepatocyte growth factor; BrdU; bromodeoxyuridine; PH; partial hepatectomy; Hepatocellular carcinoma; SOCS1; Tumor suppressor; Liver regeneration; HGF; c-Met;
Increased generation of CD8 single positive cells in SOCS1-deficient thymus does not proportionately increase their export
Keywords: T lymphocyte; Homeostasis; SOCS1; Thymic export;
Nanoparticles for ex vivo siRNA delivery to dendritic cells for cancer vaccines: Programmed endosomal escape and dissociation
Keywords: siRNA; Vaccination; Dendritic cells; SOCS1; Intracellular trafficking
The role of viruses in acute exacerbations of asthma
Keywords: Asthma; acute exacerbation; virus; BAL; Bronchoalveolar lavage; BEC; Bronchial epithelial cell; FGF; Fibroblast growth factor; HRV; Human rhinovirus; ICAM-1; Intercellular adhesion molecule 1; IP-10; Interferon-inducible protein 10; IRF; Interferon regula
Progesterone inhibits Toll-like receptor 4-mediated innate immune response in macrophages by suppressing NF-κB activation and enhancing SOCS1 expression
Keywords: Progesterone; Toll-like receptor; Proinflammatory cytokine; NF-κB; SOCS1
Overexpression of suppressor of cytokine signaling 1 in islet grafts results in anti-apoptotic effects and prolongs graft survival
Keywords: Diabetes; Islet transplantation; SOCS1; Apoptosis; Gene therapy
Disturbances in the LIF pathway in the endometrium among women with unexplained infertility
Keywords: LIF; LIFR; gp130; SOCS1; human endometrium; unexplained infertility
SOCS1 downregulation in dendritic cells promotes memory T-cell responses
Keywords: Memory; T cells; SOCS1; Vaccine
Suppressor of cytokine signaling expression with increasing severity of murine hepatic ischemia-reperfusion injury
Keywords: IR; ischemia-reperfusion; SOCS1; suppressor of cytokine signaling1; SOCS3; suppressor of cytokine signaling3; STAT1; signal transducer and activators of transcription1; STAT3; signal transducer and activators of transcription3; GPT; glutamate pyruvate tra
Demonstration of cooperative contribution of MET- and EGFR-mediated STAT3 phosphorylation to liver regeneration by exogenous suppressor of cytokine signalings
Keywords: SOCS1; SOCS3; Adenovirus vector; ERK1/2; Hepatocytegp, glycoprotein; PHx, partial hepatectomy; SOCS, suppressor of cytokine signaling; JAK, Janus-activated kinase; moi, multiplicity of infection; Ab, antibody
Overproduction of collagen and diminished SOCS1 expression are causally linked in fibroblasts from idiopathic pulmonary fibrosis
Keywords: Idiopathic pulmonary fibrosis; IFN-γ; SOCS1; Fibroblasts; Collagen
IGFBP3 Promoter Methylation in Colorectal Cancer: Relationship with Microsatellite Instability, CpG Island Methylator Phenotype, p53
Keywords: Colon cancer; IGFBP3; methylation; CIMP; MSI; BAX; BCL2-associated X protein; CACNA1G; calcium channel; voltagedependent; T type alpha-1G subunit; CDKN1A; cyclin-dependent kinase inhibitor 1A (p21, CIP1); CDKN2A; cyclin-dependent kinase inhibitor 2A (p16,
Akyrin repeat and SOCS box containing protein 4 (Asb-4) interacts with GPS1 (CSN1) and inhibits c-Jun NH2-terminal kinase activity
Keywords: Asb-4; ankyrin repeat and SOCS box-containing protein 4; Asb-4/Îsb; Asb-4 minus its SOCS box; GPS1; G-protein pathway suppressor 1; CSN1; COP9 signalosome, subunit 1; ARC; arcuate nucleus; POMC; pro-opiomelanocortin; NPY; neuropeptide Y; QDO; quadruple d
Regulation of IL-21 signaling by suppressor of cytokine signaling-1 (SOCS1) in CD8+ T lymphocytes
Keywords: SOCS1; Cytokine; IL-21; IL-15; STAT3; STAT5; T lymphocyte; Homeostasis; CD8 T cells
Immunosuppressant triptolide inhibits dendritic cell-mediated chemoattraction of neutrophils and T cells through inhibiting Stat3 phosphorylation and NF-κB activation
Keywords: Dendritic cells; Immunosuppression; Chemokine; NF-κB; STAT3; SOCS1
Oligodendrocytes exhibit selective expression of suppressor of cytokine signaling genes and signal transducer and activator of transcription 1 independent inhibition of interferon-gamma-induced toxicity in response to leukemia inhibitory factor
Keywords: oligodendrocyte; SOCS1; SOCS3; leukemia inhibitory factor; interferon gamma; signal transductionBSA, bovine serum albumin; CNTF, ciliary neurotrophic factor; EAE, experimental autoimmune encephalomyelitis; IFNγ, interferon-gamma; IL, interleukin; JAK, jan
Toll-Like Receptor Signaling in the Liver
Keywords: ER; endoplasmic reticulum; LPS; lipopolysaccharide; LRR; leucine-rich repeat; PAMPs; pathogen-associated molecular patterns; PH; partial hepatectomy; SOCS1; suppressing of cytokine signaling 1; TIR; Toll/interleukin-1 receptor; TIRAP; TIR domain containin
In silico identification of the key components and steps in IFN-γ induced JAK-STAT signaling pathway
Keywords: IFN-γ; interferon gamma; JAK; Janus kinase; STAT; signal transducers and activators of transcription; IFNR; interferon-γ receptor; RJ; IFNR-JAK complex; STAT1; signal transducer and activator of transcription 1; SHP-2; SH2 domain-containing tyrosine p