Keywords: حلال گویینیل سیکلاس; BCA; Bicinchoninic acid; CK; Creatine kinase; CP; Creatine phosphate; DEAE; Diethylaminoethanol; DEA/NO; 2,2-Diethyl-1-nitroso-oxyhydrazine; DTPA; Diethylenetriaminepentaacetic acid; DTT; Dithiothreitol; FPLC; Fast protein liquid chromatography; GSNO; S-n
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Fermented garlic extract ameliorates monocrotaline-induced pulmonary hypertension in rats
Keywords: حلال گویینیل سیکلاس; Fermented garlic; Monocrotaline; Pulmonary hypertension; Nitrite; Soluble guanylyl cyclase; Inflammation;
Keywords: حلال گویینیل سیکلاس; CCR; counterregulatory responses; CNS; central nervous system; L-NAME; NÏ-Nitro-l-arginine methyl ester; LS; lateral amygdala; LTP; long term potentiation; NO; nitric oxide; NOS; NO synthase; NTS; nucleus tractus solitarius; PVH; paraventricular hypothal
Keywords: حلال گویینیل سیکلاس; â(â)epigallocatechin gallate; Peroxynitrite; Soluble guanylyl cyclase;
Keywords: حلال گویینیل سیکلاس; ANP; atrial natriuretic peptide; BKCa; large-conductance Ca2Â + activated potassium channels; cAMP; cyclic adenosine 3,5â²-monophosphate; CNG; cyclic nucleotide-gated; cGMP; cyclic guanosine 3,5â²-monophosphate; HUASMC; human umbilical artery smooth mus
Keywords: حلال گویینیل سیکلاس; CIITA; class II major histocompatibility complex transactivator; GR; glucocorticoid receptor; MIF; macrophage migration inhibitory factor; sGC; soluble guanylyl cyclase; Acute stress; Hippocampus; Nitric oxide; Nitric oxide synthase; Pro-inflammatory cyto
Keywords: حلال گویینیل سیکلاس; Corpora Cavernosa; Erectile Function; Oxime; Soluble Guanylyl Cyclase; Oxidative Stress
Keywords: حلال گویینیل سیکلاس; 7NI; 7-Nitroindazole; AB; angular bundle; AD; after discharge; AED; antiepileptic drugs; AM251; N-(piperidin-1-yl)-5-(4-iodophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; ANOVA; analysis of variance; CBr; cannabinoid receptors; DG; den
Keywords: حلال گویینیل سیکلاس; cNMPs; Nucleotidyl cyclases; Phosphodiesterases; Protein kinases; Bacterial toxins; Second messengers; AC; adenylyl cyclase; cAMP; adenosine 3â²,5â²-cyclic monophosphate; CC; cytidylyl cyclase; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanos
Keywords: حلال گویینیل سیکلاس; COPD; Asthma; Nitric oxide; Soluble guanylyl cyclase
Keywords: حلال گویینیل سیکلاس; Benzothiazoles; Rat aorta; Soluble guanylyl cyclase; cGMP; L-type Ca2+ channel;
Keywords: حلال گویینیل سیکلاس; Cav3; caveolin-3; Cav3+LR; caveolin-3 enriched lipid raft, caveolae; cGMP; cyclic guanosine monophosphate; DEA/NO; diethylammonium (Z)-1-(N,N-diethylamino)diazen-1-ium-1,2-diolate, diethylamine NONOate; ERK5; extracellular signal regulated kinase 5; LR; l
Endothelium-derived hyperpolarizing factor and protein kinase G Iα activation: H2O2 versus S-nitrosothiols
Keywords: حلال گویینیل سیکلاس; Protein kinase G Iα; Endothelium-derived hyperpolarizing factors; Thioredoxin reductase; Soluble guanylyl cyclase; S-nitrosothiols;
Nitric oxide and cyclic GMP functions in bone
Keywords: حلال گویینیل سیکلاس; Nitric oxide; cGMP; Soluble guanylyl cyclase; Protein kinase G; Bone; Osteoporosis; Osteoblasts; Osteoclasts; Mechanotransduction; Estrogen deficiency;
Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists
Keywords: حلال گویینیل سیکلاس; 4-AP; 4-amynopiridine; AC; adenylyl cyclase; BPH; benign prostatic hyperplasia; COX; cyclooxygenase; DAG; diacylglycerol; EDHF; endothelium-derived hyperpolarizing factor; eNOS; endothelial NO synthase; GLI; glibenclamide; HAEC; human aortic endothelial c
Redox regulation of soluble guanylyl cyclase
Keywords: حلال گویینیل سیکلاس; Soluble guanylyl cyclase; Heme; Redox; Thiol; Localization; Therapeutics;
Cardiac natriuretic peptides promote adipose 'browning' through mTOR complex-1
Keywords: حلال گویینیل سیکلاس; Thermogenesis; UCP1; Kinases; βAR; β-adrenergic receptor; 8-Br-cAMP; 8-Bromoadenosine 3â²,5â²-cyclic monophosphate; 8-Br-cGMP; 8-Bromoguanosine 3â²,5â²-cyclic monophosphate; Akt; protein kinase B; ANP; Atrial natriuretic peptide; BNP; B-type natriur
Mercaptopyruvate acts as endogenous vasodilator independently of 3-mercaptopyruvate sulfurtransferase activity
Keywords: حلال گویینیل سیکلاس; Mercaptopyruvate; Hydrogen sulfide; Vasorelaxation; Aorta; 3-Mercaptopyruvate sulfurtransferase knockout mice; 3-MST; 3-mercaptopyruvate sulfurtransferase; CAT; cysteine aspartate aminotransferase; CBS; cystathionine-β-synthase; CSE; cystathionine-γ-lya
Regulation of vascular tone homeostasis by NO and H2S: Implications in hypertension
Keywords: حلال گویینیل سیکلاس; ADRF; adipocyte-derived relaxing factor; AE; anion exchanger; ATP; adenosine triphosphate; BH4; tetrahydrobiopterin; BKCa; big conductance Ca2+-sensitive K+ channel; CaM; calmodulin; cAMP; cyclic adenosine monophosphate; CAT; cysteine aminotransferase; CB
Biased activity of soluble guanylyl cyclase: the Janus face of thymoquinone
Keywords: حلال گویینیل سیکلاس; Thymoquinone; Endothelium-dependentcontraction; Nitric oxide; Soluble guanylyl cyclase; Cyclic IMP; NADPH:quinone oxidoreductase;
Endogenous nitric oxide inhibits spinal NMDA receptor activity and pain hypersensitivity induced by nerve injury
Keywords: حلال گویینیل سیکلاس; Synaptic plasticity; Synaptic transmission; Signal transduction; Ion channel; Neuropathic pain; Dorsal horn neurons; NO; nitric oxide; nNOS; neuronal nitric oxide synthase; NMDAR; N-methyl-d-aspartate receptor; ODQ; 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1
Gaseous ligand selectivity of the H-NOX sensor protein from Shewanella oneidensis and comparison to those of other bacterial H-NOXs and soluble guanylyl cyclase
Keywords: حلال گویینیل سیکلاس; H-NOX; Gaseous ligand selectivity; Soluble guanylyl cyclase; Sliding scale rule; H-NOX; heme nitric oxide and oxygen binding protein; Cb H-NOX; H-NOX from Clostridium botulinum; Lb; leghemoglobin; Ns H-NOX; H-NOX from Nostoc sp. PCC7120; So H-NOX; H-NOX f
Nitric oxide-coupled signaling in odor elicited molecular events in the olfactory center of the terrestrial snail, Helix pomatia
Keywords: حلال گویینیل سیکلاس; 5-HT; 5-hydroxytryptamine or serotonin; ACh; acetylcholine; AGC-S-P; phosphorylated substrate of the AGC-family protein kinase; Akt; protein kinase B; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid; APV; (2R)-amino-5-phosphonovaleric acid; B
Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain
Keywords: حلال گویینیل سیکلاس; ATF3; Activating transcription factor-3; ADF; Actin depolymerizing factor; cGMP; cyclic guonosine monophosphate; Cre; Cre recombinase; DRG; Dorsal root ganglia; EYFP; Enhanced yellow fluorescent protein; GAP43; Growth associated protein 43; IP3; Inositol
The NO-heme signaling hypothesis
Keywords: حلال گویینیل سیکلاس; Heme; Nitric oxide; NO-heme signaling; S-nitrosation; Soluble guanylyl cyclase;
Redox regulation of cardiovascular inflammation - Immunomodulatory function of mitochondrial and Nox-derived reactive oxygen and nitrogen species
Keywords: حلال گویینیل سیکلاس; AP-1; activator protein-1; AT1R; angiotensin II receptor type 1; AT-II; angiotensin II; bFGF; basic fibroblast growth factor; CCR; C-C chemokine receptor; cGMP; cyclic guanosine monophosphate; DC; dendritic cell; eNOS; endothelial nitric oxide synthase;
Involvement of Heme Oxygenase-1 in particulate matter-induced impairment of NO-dependent relaxation in rat intralobar pulmonary arteries
Keywords: حلال گویینیل سیکلاس; SRM1648; Standard Reference Materials 1648; HO-1; Heme Oxygenase-1; sGC; soluble Guanylyl Cyclase; NO; nitric oxide; PM; particulate matter; Particulate matter; Nitric oxide; Pulmonary artery; Heme Oxygenase-1;
Fermented garlic extract decreases blood pressure through nitrite and sGC-cGMP-PKG pathway in spontaneously hypertensive rats
Keywords: حلال گویینیل سیکلاس; Fermentation; Garlic; Hypertension; Nitrite; Soluble guanylyl cyclase; Protein kinase G;
The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia-reperfusion injury in the rat heart ex vivo
Keywords: حلال گویینیل سیکلاس; AC; adenylyl cyclase; AS; Angeli's salt; β1-AR; β1-adrenoceptor; CGRP; calcitonin gene-related peptide; CK; creatine kinase; DEA/NO; diethylamine NONOate; DOB; dobutamine; DRC; dose-response curve; HF; heart failure; HNO; nitroxyl; I-R; ischaemia-
Peroxiredoxin-2 nitrosylation facilitates cardiomyogenesis of mouse embryonic stem cells via XBP-1s/PI3K pathway
Keywords: حلال گویینیل سیکلاس; ES cell; embryonic stem cell; EB; embryoid body; DHE; Dihydroethidium; DHR; Dihydrorhodamine 123; DTT; Dithiothreitol; GO; Gene Ontology; GSNO; S-nitrosoglutathione; H2O2; hydrogen peroxide; NO; nitric oxide; ODQ; 1H-[1,2,4]oxadiazolo[4,3a]quinoxalin-1-on
Rat aorta as a pharmacological tool for in vitro and in vivo studies
Keywords: حلال گویینیل سیکلاس; BH4; tetrahydrobiopterin; cGMP; cyclic guanine monophosphate; COX; cyclooxygenase; cNOS; constitutive NOS; DAG; diacylglycerol; DMEM; Dulbecco's modified eagle's medium; eNOS; endothelial NOS; EDHF; endothelium dependent hyperpolarization factor; EGTA; et
S-nitrosylation of PDE5 increases its ubiquitin-proteasomal degradation
Keywords: حلال گویینیل سیکلاس; cGMP; cyclic guanosine monophosphate; DETA-NO; diethylenetriamine NONOate; GSNO; S-nitrosoglutathione; KT5823; 2,3,9,10,11,12-hexahydro-10R-methoxy-2,9-dimethyl-1-oxo-9S,12R-epoxy-1H-diindolo[1,2,3-fg:3â²,2â²,1â²-kl]pyrrolo[3][1,6]benzodiazocine-10-car
Research ReportEndurance training upregulates the nitric oxide/soluble guanylyl cyclase/cyclic guanosine 3â²,5â²-monophosphate pathway in the striatum, midbrain and cerebellum of male rats
Keywords: حلال گویینیل سیکلاس; Brain-derived neurotrophic factor; Endurance training; Soluble guanylyl cyclase; Locomotion; Nitric oxide synthase;
Temporal and organ-specific detection of cNMPs including cUMP in the zebrafish
Keywords: حلال گویینیل سیکلاس; Cyclic CMP; Cyclic UMP; Zebrafish; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cIMP; inosine 3â²,5â²-cyclic monophosphate; cNMP; nucleoside 3â²,5â²-cycl
The reaction products of sulfide and S-nitrosoglutathione are potent vasorelaxants
Keywords: حلال گویینیل سیکلاس; ABS; absorbance; AS; Angeli's salt; AUC; area under the curve; cPTIO; 2-(4-carboxyphenyl)-4,4,5,5-tetramethylimidazoline-1-oxyl-3-oxide; GSNO; S-nitrosoglutathione; EPR; electron paramagnetic resonance; MGD; N-(dithiocarboxy)-N-methyl-D-glucamine; NAC; N-
cAMP, cGMP, cCMP and cUMP concentrations across the tree of life: High cCMP and cUMP levels in astrocytes
Keywords: حلال گویینیل سیکلاس; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; nucleoside 3â²,5â²-cyclic monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; pGC; particulate
Soluble adenylyl cyclase accounts for high basal cCMP and cUMP concentrations in HEK293 and B103 cells
Keywords: حلال گویینیل سیکلاس; cAMP; adenosine 3â²,5â²-cyclic monophosphate; cGMP; guanosine 3â²,5â²-cyclic monophosphate; cCMP; cytidine 3â²,5â²-cyclic monophosphate; cNMP; 3â²,5â²-cyclic nucleoside monophosphate; cUMP; uridine 3â²,5â²-cyclic monophosphate; pGC; particulate
Nitric oxide improves the hemodynamic performance of the hypoxic goldfish (Carassius auratus) heart
Keywords: حلال گویینیل سیکلاس; NOS; nitric oxide synthase; NO; nitric oxide; SV; stroke volume; sGC; soluble guanylyl cyclase; HIF-1α; hypoxia inducible factor α; Hb; hemoglobin; CO; cardiac output; HR; heart rate; SW; stroke work; L-NMMA; NG-monomethyl-L-arginine; GSNO; S-nitrosoglu
Redox-dependent regulation of the Na+-K+ pump: New twists to an old target for treatment of heart failure
Keywords: حلال گویینیل سیکلاس; NADPH oxidase; nicotinamide adenine dinucleotide phosphate-oxidase; [Na+]i; intracellular Na+ concentration; Ip; electrogenic Na+-K+ pump current; ACE; angiotensin converting enzyme; AR; adrenergic receptor; NO; nitric oxide; PKA; protein kinase A; PKC;
Nitroxyl (HNO) suppresses vascular Nox2 oxidase activity
Keywords: حلال گویینیل سیکلاس; cGMP; cyclic guanosine monophosphate; cGK; cGMP-dependent protein kinase; IPA/NO; isopropylamine NONOate; MCA; middle cerebral artery; ODQ; 1H-[1,2,4]-oxadiazolo[4,3-a]quinoxalin-1-one; PDBu; phorbyl 12,13-dibutyrate; ROS; reactive oxygen species; Rp-8-pC
The type II cGMP dependent protein kinase regulates GluA1 levels at the plasma membrane of developing cerebellar granule cells
Keywords: حلال گویینیل سیکلاس; AMPA; α-amino-3-hydroxyl-5-methyl-4-isoxazole-propionate; AMPAR; AMPA receptor; Angeli's salt; disodium diazem-1-ium-1,2,2-triolate; CaCMKII; Ca2 +-calmodulin kinase II; cGK; cGMP-dependent protein kinase; cGKI; cGMP-dependent protein kinase type I; cGK
Angiotensin (5-8) modulates nociception at the rat periaqueductal gray via the NO-sGC pathway and an endogenous opioid
Keywords: حلال گویینیل سیکلاس; AA; antinociceptive activity; Angs; angiotensins; Ang-R; Ang receptor; ANOVA; analysis of variance; AT; Ang type; ATR; Ang type receptor; DMSO; dimethylsulfoxide; HR; heart rate; MAP; mean arterial pressure; nNOS; neuronal nitric oxide synthase; NO; nitri
Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91phox to the protective effect of 5,14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia, and inflammation in a rat model of septic shock
Keywords: حلال گویینیل سیکلاس; 20-HEDE; 20-hydroxyeicosa-6(Z),15(Z)-dienoic acid; AA; arachidonic acid; 20-HETE; 20-hydroxyeicosatetraenoic acid; 5,14-HEDGE; N-[20-hydroxyeicosa-5(Z),14(Z)-dienoyl]glycine; 1,3-PBIT; phenylene-1,3-bis(ethane-2-isothiourea) dihydrobromide; cDNA; compleme
Role of nitric oxide in the regulation of motor function. An overview of behavioral, biochemical and histological studies in animal models
Keywords: حلال گویینیل سیکلاس; cGMP; nitric oxide; locomotor activity; 6-OHDA; Parkinson's disease; soluble guanylyl cyclase
Analysis of responses to glyceryl trinitrate and sodium nitrite in the intact chest rat
Keywords: حلال گویینیل سیکلاس; GTN; glyceryl trinitrate/nitroglycerin; GDN; glyceryl dinitrate; NO; nitric oxide; S-NO; S-nitrosothiol; GSNO; S-nitrosoglutathione; sGC; soluble guanylyl cyclase; ALDH2; mitochondrial aldehyde dehydrogenase; XOR; xanthine oxidoreductase; ODQ; 1H-[1,2,4]-
Immunohistochemical and functional characterization of nitric oxide signaling pathway in isolated aorta from Crotalus durissus terrificus
Keywords: حلال گویینیل سیکلاس; Aorta; Crotalus durissus; Nitric oxide synthase; Phosphodiesterase type 5; Soluble guanylyl cyclase;
YC-1 potentiates cAMP-induced CREB activation and nitric oxide production in alveolar macrophages
Keywords: حلال گویینیل سیکلاس; AC; adenylate cyclase; CREB; cAMP response element-binding protein; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NO; nitric oxide; PDE; phosphodiesterase; PKA; protein kinase A; PG; prostaglandin; sGC; soluble guanylyl cyclase; YC-1; 3-
Nitric oxide signaling modulates cholinergic synaptic input to projection neurons in Drosophila antennal lobes
Keywords: حلال گویینیل سیکلاس; Ach; acetylcholine; ALs; antennal lobes; BSA; bovine serum albumin; cGMP; cyclic guanosine monophosphate; CNS; central nervous system; CS; Canton-S; DMSO; dimethyl sulfoxide; EGTA; ethylene glycol tetraacetic acid; EPSPs; excitatory postsynaptic potential
Nitric oxide synthase and cyclic GMP signaling in cardiac myocytes: From contractility to remodeling
Keywords: حلال گویینیل سیکلاس; cGMP; Cardiovascular disease; Soluble guanylyl cyclase; Natriuretic peptide receptor; PKG; Phosphodiesterases;
Mechanism of 1-deamino-arginine vasotocin induced natriuresis in rats
Keywords: حلال گویینیل سیکلاس; 1dAVT; 1-deamino-arginine vasotocin; ANP; atrial natriuretic peptide; AVP; arginine vasopressin; AVТ; arginine vasotocin; COX; cyclooxygenase; ELISA; enzyme-linked immunosorbent assay; L-NAME; NÏ-nitro-L-arginine methyl ester hydrochloride, inhibitor of