دانلود مقالات ISI درباره Sp600125 + ترجمه فارسی

RBBP6 promotes human cervical carcinoma malignancy via JNK signaling pathway

Keywords: Retinoblastoma binding protein 6 (RBBP6); Cervical carcinoma; SiHa and C33a cell lines; C-Jun NH2-terminal kinase (JNK); SP600125;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2018 سفارش ترجمه

Transcriptional regulation of the cyclin-dependent kinase inhibitor, p21CIP1/WAF1, by the chelator, Dp44mT

Keywords: 311; 2-hydroxy-1-naphthylaldehyde isonicotinoyl hydrazone; Act D; actinomycin D; DFO; desferrioxamine; Dp44mT; di-2-pyridylketone 4,4-dimethyl-3-thiosemicarbazone; SP; SP600125; Sp1; specificity protein 1; WT; wild-type; Iron chelator; Desferrioxamine; Dp

دانلود رایگان متن کامل مقاله ISI 59 صفحه سال انتشار : 2018 سفارش ترجمه

CFTR modulates RPS27 gene expression using chloride anion as signaling effector

Keywords: CFTR; RPS27; Chloride; Signaling effector; IL-1β; JNK; Autocrine; IL-1β loop; IL1RN; SP600125;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2017 سفارش ترجمه

JNK1/2 inhibitor reduces dengue virus-induced liver injury

Keywords: Dengue virus; JNK; Liver injury; Apoptosis; SP600125;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2017 سفارش ترجمه

SP600125 enhances the anti-apoptotic capacity and migration of bone marrow mesenchymal stem cells treated with tumor necrosis factor-α

Keywords: BMSCs; TNF-α; SP600125; Apoptosis; Migration;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of c-Jun N-terminal kinase signaling suppresses skin flap apoptosis in a rat ischemia and/or reperfusion model

Keywords: Skin; Ischemia/reperfusion; JNK; SP600125; Hydrogen;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

SP600125 promotes resolution of allergic airway inflammation via TLR9 in an OVA-induced murine acute asthma model

Keywords: Acute asthma; Allergic airway inflammation; JNK; SP600125; TLR9;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Inhibition of development of experimental abdominal aortic aneurysm by c-jun N-terminal protein kinase inhibitor combined with lysyl oxidase gene modified smooth muscle progenitor cells

Keywords: SP600125 (PubChem CID: 8515)Abdominal aortic aneurysm; C-Jun N-terminal protein kinase; Drug delivery system; Smooth muscle progenitor cell; SP600125

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Map2k4δ - Identification and functional characterization of a novel Map2k4 splice variant

Keywords: AKT; protein kinase B; ATF-2; activating transcription factor 2; BrdU; 5-bromo-2-deoxyuridine; DVD; domain of versatile docking; E; embryonic day; ERK; extracellular signal-regulated kinase; Fas-L; Fas ligand; ID; immunodepletion; IP; immunoprecipitation;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells

Keywords: ASK-1; apoptosis signal-regulating kinase 1; dexa; dexamethasone; eIF2α; eukaryotic translation initiation factor 2α; GC; glucocorticoid; GR; glucocorticoid receptor; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PP5; serine/thre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

TP53 mutation-correlated genes predict the risk of tumor relapse and identify MPS1 as a potential therapeutic kinase in TP53-mutated breast cancers

Keywords: Breast cancer subtypes; TP53 mutation status; Tumor relapse; MPS1 protein kinase; SP600125; Chemotherapy;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of c-Jun NH2-terminal kinase stimulates mu opioid receptor expression via p38 MAPK-mediated nuclear NF-κB activation in neuronal and non-neuronal cells

Keywords: MOR; mu opioid receptor; JNK; c-Jun NH2-terminal kinase; MAPK; mitogen-activated protein kinase; MEK; mitogen-activated protein/extracellular signal-regulated kinase; NF-κB; nuclear factor-kappaB; DP; distal promoter; PP; proximal promoter; Oct-1; octame

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest

Keywords: Sal; salinomycin; PAC; paclitaxcel; DOC; docetaxcel; VIN; vinblastine; COL; colchicine; DOX; doxorubicin; ETO; etoposide; SP; SP600125; P-gp; p-glycoprotein; DMSO; dimethylsulfoxide; FACS; fluorescence-activated cell sorting; FBS; fetal bovine serum; TCA;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

SP600125 inhibits Orthopoxviruses replication in a JNK1/2 -independent manner: Implication as a potential antipoxviral

Keywords: Poxvirus; SP600125; Antipoxviral; Antiviral; JNK; Morphogenesis;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

The effects of metabotropic glutamate receptor 7 allosteric agonist N,N′-dibenzhydrylethane-1,2-diamine dihydrochloride on developmental sevoflurane neurotoxicity: role of extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase si

Keywords: mGluRs; sevoflurane; neurotoxicity; MAPK; learning and memory; hippocampus; AMN082; N,N′-dibenzhydrylethane-1,2-diamine dihydrochloride; EDTA; ethylenediaminetetraacetic acid; ERK1/2; extracellular signal-regulated kinase 1 and 2; FCM; Flow cytometry; H

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

P2 receptor stimulation induces amyloid precursor protein production and secretion in rat cortical astrocytes

Keywords: 2MeSADP; 2-methylthio-ADP; 8PSPT; 8-(p-sulfophenyl)-theophylline; AD; Alzheimer's disease; APP; amyloid precursor protein; BzATP; 3′-O-(4-benzoyl)benzoyl-ATP; DAPI; 4′-6-diamidino-2-phenylindole; DMEM; Dulbecco's modified Eagle's medium; ERK; extracel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

Research reportInhibition of JNK phosphorylation reverses memory deficit induced by β-amyloid (1-42) associated with decrease of apoptotic factors

Keywords: β-amyloid; Alzheimer; Apoptosis; JNK; SP600125; Morris water maze; Rat;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Blocking Daxx trafficking attenuates neuronal cell death following ischemia/reperfusion in rat hippocampus CA1 region

Keywords: Cerebral ischemia; Daxx trafficking; Ask1; Fas; NAC; SP600125;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

TSU-16, (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone, is a potent activator of aryl hydrocarbon receptor and increases CYP1A1 and CYP1A2 expression in human hepatocytes

Keywords: VEGF; vascular endothelial growth factor; VEGFR; vascular endothelial growth factor receptor; TSU-16; (Z)-3-[(2,4-dimethylpyrrol-5-yl)methylidenyl]-2-indolinone; CYP; cytochrome P450; AhR; aryl hydrocarbon receptor; OMP; omeprazole; 3MC; 3-methylcholanthr

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

SP600125, a competitive inhibitor of JNK attenuates streptozotocin induced neurocognitive deficit and oxidative stress in rats

Keywords: SP600125; JNK; Streptozotocin; Dementia; Neurocognitive dysfunction; Oxidative stress; Alzheimer's disease;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2010 سفارش ترجمه

Hepatitis C Virus Regulates Transforming Growth Factor β1 Production Through the Generation of Reactive Oxygen Species in a Nuclear Factor κB-Dependent Manner

Keywords: Hepatitis C Virus; Reactive Oxygen Species; Nuclear Factor κB; Transforming Growth Factor β1; AQ; 6-amino-4-(4-phenoxyphenylethylamino) quinazoline; DMSO; dimethyl sulfoxide; DPI; diphenyliodonium; ECL; electrochemiluminescence; ERK; extracellular signa

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

The c-Jun N-terminal kinase inhibitor SP600125 is neuroprotective in amygdala kindled rats

Keywords: Kindling; Temporal lobe epilepsy; Hippocampal sclerosis; Neuronal defect; JNK; SP600125;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2010 سفارش ترجمه

SP600125 negatively regulates the mammalian target of rapamycin via ATF4-induced Redd1 expression

Keywords: ATF4; JNK; Mammalian target of rapamycin; Redd1; SP600125;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Up-regulation of CAR expression through Elk-1 in HepG2 and SW480 cells by serum starvation stress

Keywords: Constitutive androstane receptor; Serum starvation; Elk-1; SP600125; HepG2 cell; SW480 cellAhR, aryl hydrocarbon receptor; CAR, constitutive androstane receptor; DMEM, Dulbecco’s modified Eagle’s medium; FCS, fetal calf serum; HNF4α, hepatocyte nuclear fa

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2009 سفارش ترجمه

Neuroprotection by c-Jun NH2-terminal kinase inhibitor SP600125 against potassium deprivation–induced apoptosis involves the Akt pathway and inhibition of cell cycle reentry

Keywords: SP600125; c-Jun NH2-terminal kinase; Akt; cell cycle; cerebellar granule cellscdk5/p35, cyclin-dependent kinase 5; CGN, cerebellar granule cell; CREB, cyclic AMP response element-binding protein; ct, cycle threshold; FOXO, Forkhead protein; GSK-3β, glycog

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2009 سفارش ترجمه

SP600125 inhibits Kv channels through a JNK-independent pathway in cancer cells

Keywords: SP600125; Voltage-dependent K+ channels; Cancer; MAPK; JNK; Patch-clamp

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2008 سفارش ترجمه

Changes in the expression and dynamics of SHP-1 and SHP-2 during cerulein-induced acute pancreatitis in rats

Keywords: SHP-1; SHP-2; Acute pancreatitis; Cerulein; SP600125; Rolipram

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2008 سفارش ترجمه

Bcl-2 overexpression attenuates SP600125-induced apoptosis in human leukemia U937 cells

Keywords: SP600125; Bcl-2; Apoptosis; G2/M phase arrest; Endoreduplication

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

TNF-α mediates pseudorabies virus-induced apoptosis via the activation of p38 MAPK and JNK/SAPK signaling

Keywords: Pseudorabies virus; p38; JNK/SAPK; SB203580; SP600125; NF-κB; Apoptosis; TNF-α

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2008 سفارش ترجمه

Induction of endoreduplication by a JNK inhibitor SP600125 in human lung carcinoma A 549 cells

Keywords: SP600125; p53; Mdm2; Endoreduplication; Cell cycle; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; ERK; extracellular-signal-regulated kinase; FBS; fetal bovine serum; PBS; phosphate buffered saline;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2007 سفارش ترجمه

SP600125, a selective JNK inhibitor, protects ischemic renal injury via suppressing the extrinsic pathways of apoptosis

Keywords: SP600125; Renal ischemia/reperfusion; JNK; c-Jun; Fas/FasL; Apoptosis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2007 سفارش ترجمه

TNFR1-induced NF-κB, but not ERK, p38MAPK or JNK activation, mediates TNF-induced ICAM-1 and VCAM-1 expression on endothelial cells

Keywords: caspase; cysteine-aspartate-directed proteases; cPLA2; cytosolic phospholipase A2; DD; death domain; ERK; extracellular signal-regulated kinase; hr-GFP; humanised renilla green fluorescent protein; HUVEC; human umbilical endothelial cells; ICAM; intracell

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2007 سفارش ترجمه

Opposing effects of Bad phosphorylation at two distinct sites by Akt1 and JNK1/2 on ischemic brain injury

Keywords: Bad phosphorylation; JNK; Akt; SP600125; bpV(pic); Cerebral ischemia; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PI3K; phosphoinositide 3-kinase; ERK; Extracellular signal regulated kinase; PKA; protein kinase A; RTK; receptor t

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2007 سفارش ترجمه

Cepharanthine triggers apoptosis in a human hepatocellular carcinoma cell line (HuH-7) through the activation of JNK1/2 and the downregulation of Akt

Keywords: CEP, cepharanthine; JNK, c-Jun N-terminal kinase; MAPK, mitogen activated protein kinase; ROS, reactive oxygen species; NAC, N-acetyl cysteine; PARP, poly-(ADP-ribose)-polymeraseCepharanthine; Apoptosis; MAPK; PARP; SP600125

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

JNK inhibitor SP600125 reduces COX-2 expression by attenuating mRNA in activated murine J774 macrophages

Keywords: COX-2; JNK; Macrophage; MAPK; SP600125; PGE2

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Neuroprotection against ischemic brain injury by SP600125 via suppressing the extrinsic and intrinsic pathways of apoptosis

Keywords: c-Jun N-terminal protein kinase (JNK); Cerebral ischemia/reperfusion; Extrinsic and intrinsic pathways of apoptosis; SP600125

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2006 سفارش ترجمه

Neuroprotection against ischemic brain injury by a small peptide inhibitor of c-Jun N-terminal kinase (JNK) via nuclear and non-nuclear pathways

Keywords: c-Jun N-terminal protein kinase; JNK; JNK interacting protein-1; JIP-1; Tat-JBD; cerebral ischemia/reperfusion; AP-1; activator-protein 1; BSA; bovine serum albumin; DTT; dithiothreitol; Fasl; Fas ligand; GluR6; glutamate receptor 6; h-DMEM; high-glucose

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2006 سفارش ترجمه

MAP1B phosphorylation is differentially regulated by Cdk5/p35, Cdk5/p25, and JNK

Keywords: Microtubule-associated protein; MAP1B; Cdk5; p35; p25; Neuronal migration; Neurodegenerative disease; Alzheimer's disease; Roscovitine; SP600125;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Negative regulation of adipogenesis from human mesenchymal stem cells by Jun N-terminal kinase

Keywords: Human mesenchymal stem cells; Adipogenesis; Osteogenesis; Jun N-terminal kinase; cAMP-response element-binding protein; Insulin receptor substrate-1; Inhibitor; SP600125;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

Geniposide activates GSH S-transferase by the induction of GST M1 and GST M2 subunits involving the transcription and phosphorylation of MEK-1 signaling in rat hepatocytes

Keywords: GST; GSH S-transferase; MEK-1; extracellular-regulated kinase kinase-1; PI 3-K; phosphotidyl inositol 3-kinase; PD; PD98059; SP; SP600125; SB; SB203580; Wt; wortmannin; ARE; antioxidant-responsive element; CDNB; 1-chloro-2, 4-dinitrobenzene; GAPDH; glycer

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه

The neuroprotective action of SP600125, a new inhibitor of JNK, on transient brain ischemia/reperfusion-induced neuronal death in rat hippocampal CA1 via nuclear and non-nuclear pathways

Keywords: Disorders of the nervous system; Ischemia; SP600125; Brain ischemia; JNK; c-Jun; Bcl-2;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2005 سفارش ترجمه

HNE increases HO-1 through activation of the ERK pathway in pulmonary epithelial cells

Keywords: AP-1; activator protein-1; EMSA; electrophoretic mobility shift assay; EpRE; electrophile response element; ERK; extracellular signal-regulated kinase; HNE; 4-hydroxynonenal; HO-1; heme oxygenase-1; HRP; horseradish peroxidase; JNK; c-Jun N-terminal kinas

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2005 سفارش ترجمه