The tyrosine phosphatase SHP2 is required for cell transformation by the receptor tyrosine kinase mutants FIP1L1-PDGFRα and PDGFRα D842V
Keywords: فاکتور سلول بنیادی; PDGFRA; PTPN11; SHP2; STAT5; Chronic eosinophilic leukemia; ERK; extracellular signal-regulated kinase; FBS; fetal bovine serum; FLT3; Fms-like tyrosine kinase 3; FPα; FIP1L1-PDGFRα; GIST; gastrointestinal stromal tumors; MAPK; mitogen-activated protein