Keywords: سولینداک; Sulindac; VPT2; FTIR; FT-Raman; UV-Vis;
مقالات ISI سولینداک (ترجمه نشده)
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Keywords: سولینداک; indomethacin; necrotizing enterocolitis; nonsteroidal antiinflammatory drugs; sulindac; tocolytics;
Keywords: سولینداک; Colon cancer; Drug delivery; FAP; Multistage vector; Silymarin; Sulindac;
A small diversity library of α-methyl amide analogs of sulindac for probing anticancer structure-activity relationships
Keywords: سولینداک; NSAID; non-steroidal anti-inflammatory drug; COX; cyclooxygenase; PG; prostaglandin; FAP; familial adenomatous polyposis; SSA; sulindac sulfide amide; SAR; structure-activity relationship; qHTS; quantitative high-throughput screen; CPC; choroid plexus car
Sulindac encapsulation and release from functional poly(HEMA) microparticles prepared in supercritical carbon dioxide
Keywords: سولینداک; 2-Hydroxyethyl methacrylate; Cross-linked particle; Microgel; Sulindac; Supercritical carbon dioxide;
Diverse amide analogs of sulindac for cancer treatment and prevention
Keywords: سولینداک; NSAID; non-steroidal anti-inflammatory drug; COX; cyclooxygenase; SSA; sulindac sulfide amide; SAR; structure-activity relationship; AA; amino acid; ALL; acute lymphoblastic leukemia; CPC; choroid plexus carcinoma; TPSA; topological polar surface area; Li
Thermal characterization of some polymorph solvates of the anti-inflammatory/anti-cancer sulindac
Keywords: سولینداک; Sulindac; Polymorph solvate; Desolvation; Decoloration; Thermal analysis; Raman spectra; QESD
Modified drug release system based on Sulindac and layered double hydroxide: An in vivo Raman investigation
Keywords: سولینداک; Sulindac; Raman; LDH; Modified drug release; Drug delivery system; NSAID;
Amino acid esters as prodrugs of an arylalkanoic acid COX inhibitor: Synthesis and biopharmaceutical and pharmacological evaluation
Keywords: سولینداک; Amino acid conjugate; Analgesic; Anti-inflammatory; Hydrolysis; Sulindac; Ulcerogenesis
Preparation and characterization of a sulindac sensor based on PVC/TOA–SUL membrane
Keywords: سولینداک; Ion-selective electrode; Sulindac; Tetraoctylammonium salt; Polymer membrane; Urine
Asymmetric oxidation of sulfides by hydrogen peroxide catalyzed by chiral manganese porphyrins in water/methanol solution
Keywords: سولینداک; Asymmetric oxidation; Catalytic sulfoxidation; Water-soluble manganese porphyrin; Hydrogen peroxide; Sulindac
Randomized phase II trial of sulindac for lung cancer chemoprevention
Keywords: سولینداک; Lung cancer; Chemoprevention; Phase II clinical trial; Sulindac; NSAIDs
Evaluating the inhibitory potential of sulindac against the bleomycin-induced pulmonary fibrosis in wistar rats
Keywords: سولینداک; Bleomycin; Lung fibrosis; Sulindac; Hydroxyproline; Tumour necrosis factor-α
Solubility of sulindac in the supercritical carbon dioxide: Experimental and modeling approach
Keywords: سولینداک; Supercritical carbon dioxide; Sulindac; Solubility; Modeling; Empirical correlation
Differential involvement of mitochondrial dysfunction, cytochrome P450 activity, and active transport in the toxicity of structurally related NSAIDs
Keywords: سولینداک; DIC; diclofenac; IBU; ibuprofen; IND; indomethacin; ETC; electron transport chain; KEP; ketoprofen; KER; ketorolac; MDR; multidrug resistance; NAP; naproxen; NSAID; non-steroidal anti-inflammatory drug; P450; cytochrome P450; ROS; reactive oxygen species;
Serum biomarker modulation following molecular targeting of epidermal growth factor and cyclooxygenase pathways: A pilot randomized trial in head and neck cancer
Keywords: سولینداک; HNSCC; Biomarkers; EGFR; COX; Erlotinib; Sulindac;
Beneficial effects of sulindac in focal cerebral ischemia: A positive role in Wnt/β-catenin pathway
Keywords: سولینداک; Cerebral ischemia; Sulindac; Wnt/β-catenin signaling; Bcl-2; Bax; Claudin-5;
COX inhibitors Indomethacin and Sulindac derivatives as antiproliferative agents: Synthesis, biological evaluation, and mechanism investigation
Keywords: سولینداک; COX inhibitor; Indomethacin; Sulindac; Anti-cancer; Tubulin inhibitorCOX, Cyclooxygenase; NSAIDs, non-steroidal anti-inflammatory drugs; PDK, phosphoinositide-dependent kinase; Hsp27, heat shock protein 27; Wnt, “Wnt” was created from a combination of the
Optimisation and validation of a fast HPLC method for the quantification of sulindac and its related impurities
Keywords: سولینداک; HPLC; Sulindac; Validation; Design space; Sub-2micron column;
Sulindac and its metabolites: Sulindac sulfide and sulindac sulfone enhance cytotoxic effects of arsenic trioxide on leukemic cell lines
Keywords: سولینداک; Arsenic trioxide; Sulindac; Sulindac sulfide; Sulindac sulfone; Leukemic cells; Apoptosis
Chemoprevention in familial adenomatous polyposis
Keywords: سولینداک; Familial adenomatous polyposis; Adenomas; Chemoprevention; Sulindac; Celecoxib; Curcumin; Eicosapentaenoic acid
Therapeutic potential of sulindac hydroxamic acid against human pancreatic and colonic cancer cells
Keywords: سولینداک; Sulindac; Hydroxamic acid; Cytotoxicity; Apoptosis; Angiogenesis
Inhibition of arachidonic acid metabolism decreases tumor cell invasion and matrix metalloproteinase expression
Keywords: سولینداک; NSAIDs; COX; LOX; Aspirin; Sulindac; NS-398; NDGA; ETYA; MMPs; Cell invasion; Head and neck cancer; Colon cancer
Phospho-Sulindac (OXT-328), a Novel Sulindac Derivative, Is Safe and Effective in Colon Cancer Prevention in Mice
Keywords: سولینداک; Colon Cancer; Phospho-Sulindac; Sulindac; Polyamines; Reactive Oxygen SpeciesBSO, buthionine sulfoximine; COX, cyclooxygenase; DCFDA, dichlorodihydrofluorescein diacetate; DFMO, difluoromethylornithine; ERK, extracellular-signal regulate kinase; GSH, glut
Inhibitory effect of nonsteroidal anti-inflammatory drugs on adenosine transport in vascular smooth muscle cells
Keywords: سولینداک; Sulindac; Adenosine transport; Smooth muscle cell
Sulindac Prevents Carcinogen-Induced Intrahepatic Cholangiocarcinoma Formation In Vivo
Keywords: سولینداک; cholangiocarcinoma; cyclooxygenase; nuclear factor κ-B; sulindac; chemoprevention
Sulindac suppresses β-catenin expression in human cancer cells
Keywords: سولینداک; Sulindac; β-catenin; p21WAF1/cip1; Proliferation; Apoptosis; Cancer
Unique MAP Kinase binding sites
Keywords: سولینداک; MAP kinases; Inhibitor binding; FXFP; Sulindac; PD98059; X-ray crystallographyCD-domain, Common docking domain; D-Motif, Docking motif or docking site in MAP kinase substrates and MAP kinase processing enzymes; DFG-out, unusual conformation in well conser
Sulindac treatment in hereditary non-polyposis colorectal cancer
Keywords: سولینداک; HNPCC; Chemoprevention; Sulindac; Proliferation; Apoptosis;
JNK1 is required for sulindac-mediated inhibition of cell proliferation and induction of apoptosis in vitro and in vivo
Keywords: سولینداک; JNK1; p21; Sulindac; Proliferation; Apoptosis
Survivin is a downstream target and effector of sulindac-sensitive oncogenic Stat3 signalling in head and neck cancer
Keywords: سولینداک; signal transducer and activator of transcription 3 (Stat3); survivin; COX; head and neck cancer; squamous cell carcinoma; sulindac
Defective acute apoptotic response to genotoxic carcinogen in small intestine of APCMin/+ mice is restored by sulindac
Keywords: سولینداک; APC; Sulindac; Genotoxic carcinogen; Apoptosis; Cell proliferation; Colorectal cancer; AARGC; Acute apoptotic response to genotoxic carcinogen; AOM; Azoxymethane; PCNA; Proliferating cell nuclear antigen; APC; Adenomatous polyposis coli (gene);
Sulindac, a nonsteroidal anti-inflammatory drug, selectively inhibits interferon-γ-induced expression of the chemokine CXCL9 gene in mouse macrophages
Keywords: سولینداک; Sulindac; NSAID; Interferon-γ; Chemokine; CXCL9; Macrophages; Gene expression; STAT1; NF-κB
Non-steroidal anti-inflammatory agents, tolmetin and sulindac, inhibit liver tryptophan 2,3-dioxygenase activity and alter brain neurotransmitter levels
Keywords: سولینداک; Tolmetin; Sulindac; Tryptophan 2,3-dioxygenase; Serotonin; Dopamine; Melatonin; Parkinson's disease; NSAIDS
Capillary electrophoresis combining field-amplified sample stacking and electroosmotic flow suppressant for analysis of sulindac and its two metabolites in plasma
Keywords: سولینداک; FASS-ES; CE; Sulindac; Metabolites; Human plasma
Effects of oral dosing paradigms (gavage versus diet) on pharmacokinetics and pharmacodynamics
Keywords: سولینداک; Oral gavage; Diet dosing; Pharmacokinetics; Pharmacodynamics; Sulindac; PGE2
Mechanisms of sulindac-induced apoptosis and cell cycle arrest
Keywords: سولینداک; Chemoprevention; Apoptosis; Sulindac; Colon cancer; Cell cycle; NSAID, non-steroidal anti-inflammatory drug; FAP, familial adenomatous polyposis; MEF, mouse embryonic fibroblast; COX, cyclooxygenase; Rb, retinoblastoma tumor suppressor protein;
Sulindac activates nuclear translocation of AIF, DFF40 and endonuclease G but not induces oligonucleosomal DNA fragmentation in HT-29 cells
Keywords: سولینداک; Sulindac; Apoptosis; HT-29; HMW DNA fragments; Nuclear translocation;