Keywords: AEP; asparagine endopeptidase; AD; Alzheimer's disease; AEP KO; AEP knockout; WT; wildtype; MWM; Morris water maze; fEPSP; field excitatory postsynaptic potential; PP; perforant pathway; DG; dentate gyrus; TBS; theta burst stimulation; LTP; long-term po
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Keywords: Neonatal handling; Attentional set shifting task; Task switching; Prefrontal cortex; Biochemical parameters; NH; neonatal handling; mPFC; medial prefrontal cortex; BDNF; brain-derived neurotrophic factor; TH; tyrosine hydroxylase; pTH; phosphorylated tyro
Keywords: WT; wild-type; KO; knockout; tau-/-; homozygous tau KO; mPTP; Mitochondrial permeability transition pore; AD; Alzheimer's disease; GR; Glucocorticoid Receptor; HO; heme oxygenase; GCS; γ-glutamine cysteine synthase; ROS; reactive oxygen species; Mfn1; Mi
Keywords: AAE; ascorbic acid equivalents; AAPH; 2,2â²-azobis-(2-amidinopropane) dihydrochloride; BB; black turtle bean; CB; cranberry bean; CC; Consul chickpea; DPPH; 2,2-diphenyl-1-picrylhydrazyl; DW; dry weight; FAME; fatty acid methyl esters; FC; Frontier chick
Keywords: FFA; Free Fatty Acid; HCD; Hypercaloric diet; LTM; long-term memory; MS; Metabolic syndrome; NCD; Normocaloric diet; NORT; Novel object recognition task; STM; Short-term memory; Syp; Synaptophysin; T2DM; Type 2 diabetes mellitus; High-calorie diet; Synapt
Keywords: 17β-HSD; 17β-hydroxysteroid dehydrogenase; ACh; acetylcholine; AChE; acetylcholinesterase; CA1; region 1 of hippocampus proper; CAT; catalase; ER; estrogen receptor; fEPSP; field excitatory postsynaptic potentials; GPx; glutathione peroxidase; HFS; high
Keywords: CNS; central nervous system; AE; acrobatic exercise; SED; sedentary rats; SYS; synapsin I; SYP; synaptophysin; MAP-2; microtubule associated protein-2; NFs; neurofilaments; IEGs; immediaty early genes; Egr-1; early growth response gene 1; LTP; long term p
Part A: Temporal and dose-dependent transcriptional responses in the liver of fathead minnows following short term exposure to the polycyclic aromatic hydrocarbon phenanthrene
Keywords: SREBF1; sterol regulatory element binding transcription factor 1; FASN; fatty acid synthase; HSD17B12; hydroxysteroid (17-beta) dehydrogenase 12; ACACA; acetyl-CoA carboxylase alpha; CYB5A; cytochrome b5 type A (microsomal); SLC27A4; solute carrier family
Etidronate-zinc Complex Ameliorated Cognitive and Synaptic Plasticity Impairments in 2-Vessel Occlusion Model Rats by Reducing Neuroinflammation
Keywords: 2-VO; two-vessel occlusion; BPs; bisphosphonates; CCH; chronic cerebral hypoperfusion; COX-2; cyclooxygenase-2; DEP; depotentiation; Eti; etidronate; Eti-Zn; etidronate-zinc complex; fEPSP; field excitatory postsynaptic potential; Iba1; ionized calciu
Fluoride-induced alterations of synapse-related proteins in the cerebral cortex of ICR offspring mouse brain
Keywords: NaF; Memory disrupt; Cytoskeleton; SYP; Dbn; Neurotransmitter receptor;
Astaxanthin: A mechanistic review on its biological activities and health benefits
Keywords: Astaxanthin (PubChem CID: 5368397); Beta-Carotene (PubChem CID: 5280489); Beta-Cryptoxanthin (PubChem CID: 5281235); Canthaxanthin (PubChem CID: 5281227); Lutein (PubChem CID: 5281243); Zeaxanthin (PubChem CID: 5280899); Alpha-Tocopherol (PubChem CID: 149
Neurodevelopmental synaptopathies: Insights from behaviour in rodent models of synapse gene mutations
Keywords: Mouse models; Behaviour; Epilepsy; Intellectual disability; Autism spectrum disorder; Schizophrenia; Â â/â; Â homozygous mutation; Â +/â; Â heterozygous mutation; Â â/Y; hemizygous mutation; DLG; discs large homolog; DLGAP; DLG associated protein
From stroke to neurodegenerative diseases: The multi-target neuroprotective effects of 3-n-butylphthalide and its derivatives
Keywords: 2-VO; 2 vessel occlusion; Aβ; amyloid-β protein; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; Br-NBP; 3-butyl-6-bromo-1(3âH)-isobenzofuranone; BZP; sodium(±)-5-bromo-2-(a-hydroxypentyl) benzoate; CFDA
Mutations in two large pedigrees highlight the role of ZNF711 in X-linked intellectual disability
Keywords: ADID; autosomal dominant intellectual disability; ARID; autosomal recessive intellectual disability; CADD; Combined Annotation Dependent Depletion; cDNA; complementary deoxyribonucleic acid; DNA; deoxyribonucleic acid; ExAC; Exome Aggregation Consortium;
Dexibuprofen prevents neurodegeneration and cognitive decline in APPswe/PS1dE9 through multiple signaling pathways
Keywords: AD; Alzheimer's disease; Aβ; Amyloid beta; APP; Amyloid precursor protein; NFTs; Neurofibrillary tangles; BACE1; β-secretase 1; TNF-α; Tumor necrosis factor; iNOS; Inducible nitric oxide synthase; NSAIDs; Non-steroidal anti-inflammatory drugs; PPARγ;
Fluorocitrate induced the alterations of memory-related proteins and tau hyperphosphorylation in SD rats
Keywords: FC; fluorocitrate; GSK-3β; glycogen synthase kinase-3β; pS9; phosphorylated GSK-3β at serine 9; PP2A; protein phosphatase-2A; PP2AC; PP2A catalytic subunit; pY307; phosphorylated PP2A catalytic subunit at tyrosine-307; CREB; cAMP response element bindi
Critical role of JSAP1 and JLP in axonal transport in the cerebellar Purkinje cells of mice
Keywords: APP; amyloid precursor protein; cDKO; conditional double KO; cKO; conditional KO; cTKO; conditional triple KO; Cyt c; cytochrome c; DAPI; 4,6-diamidino-2-phenylindole; DCN; deep cerebellar nuclei; floxed; loxP-flanked; GFAP; glial fibrillary acidic protei
Co-expression of TTF-1 and neuroendocrine markers in the human fetal lung and pulmonary neuroendocrine tumors
Keywords: AC; atypical carcinoid tumors; CgA; chromogranin A; NCAM; neuron cell adhesion molecule; NEBs; neuroendocrine bodies; NECs; neuroendocrine cells; NETs; neuroendocrine tumors; SCLC; small cell lung cancer; Syp; synaptophysin; TC; typical carcinoid tumors;
Abnormal cortical lysosomal β-hexosaminidase and β-galactosidase activity at post-synaptic sites during Alzheimer's disease progression
Keywords: CT-B; cholera toxin B subunit; flot-2; flotillin-2; Gal; β-galactosidase; GM1; Galβ1,3GalNAcβ1,4-(NeuAcα2,3)-Galβ1,4Glc-ceramide; GM2; 3GalNAcβ1,4-(NeuAcα2,3)-Galβ1,4Glc-ceramide; GM3; NeuAcα2,3Galβ1,4Glc-ceramide; GSL; glycosphingolipid; Hex; Î
The mitochondrial aspartate/glutamate carrier isoform 1 gene expression is regulated by CREB in neuronal cells
Keywords: Aβ; β-amyloid; AGC1; aspartate/glutamate carrier isoform 1; APP; amyloid precursor protein; BAPTA-AM; 1,2-bis(2-aminophenoxy) ethane-N,N,Nâ²,Nâ²-tetraacetic acid tetrakis(acetoxymethyl ester); ChIP; chromatin immunoprecipitation; P-CREB; phospho-cAMP-
Systematic analysis of time-dependent neural effects of soluble amyloid β oligomers in culture and in vivo: Prevention by scyllo-inositol
Keywords: Aβ; amyloid β-protein; AD; Alzheimer's disease; IP; immunoprecipitation; SEC; size exclusion chromatography; AβM; Aβ monomers; AβD; LDS-stable Aβ dimers; Chiro; chiro-inositol; Scyllo; scyllo-inositol; ICC; immunocytochemistry; IHC; immunohistochemi
SO2 inhalation causes synaptic injury in rat hippocampus via its derivatives in vivo
Keywords: SO2; Developing hippocampal neurons; Synaptic plasticity; Ischemic injury; Cognitive impairment; SO2; sulfur dioxide; SYP; synaptophysin; SV; synaptic vesicle; AD; Alzheimer's disease; PSD; postsynaptic densities; ERK; extracellular signal-regulated pro
Association between SYP with attention-deficit/hyperactivity disorder in Chinese Han subjects: Differences among subtypes and genders
Keywords: SYP; ADHD; Inattentive subtype; Gender; Association
Schizophrenia as a neuronal synaptic disorder related to multiple rare genetic mutations
Keywords: Association and functional studies; GAP-43; NRGN; Rare variants; Schizophrenia; SYP
Genetic and functional analyses of the gene encoding synaptophysin in schizophrenia
Keywords: Synaptophysin; SYP; Schizophrenia; Rare variants; Association and functional study;
Research reportInvolvement of GPR12 in the induction of neurite outgrowth in PC12 cells
Keywords: FGF; fibroblast growth factor; NGF; nerve growth factor; cAMP; cyclic AMP; PKA; protein kinase A; GPCR; G protein-coupled receptor; SYP; synaptophysin; MAP-2; microtubule-associated protein-2; GPR12; Phosphor-Erk1/2; Synaptophysin; Bcl-xL; Bcl-2;
Mesenchymal stem cells enhance GABAergic transmission in co-cultured hippocampal neurons
Keywords: AraC; arabinoside C; BDNF; brain-derived neurotrophic factor; BSA; bovine serum albumin; DIV; day in vitro; ELISA; enzyme-linked immunosorbent assay; GDB; gelatin dilution buffer; GFAP; glial fibrillary acidic protein; MEM; minimum essential medium; MSC;
Gene and protein analysis of brain derived neurotrophic factor expression in relation to neurological recovery induced by an enriched environment in a rat stroke model
Keywords: BDNF; brain derived neurotrophic factor; GFAP; glial fibrillary acidic protein; GAPDH; glyceraldehyde 3-phosphate dehydrogenase; IPT; inclined plane test; MAP-2; microtubular-associated protein 2; matBDNF; mature BDNF; MCA; middle cerebral artery; NSS; ne
Immunohistochemical evidence for synaptic release of glutamate from orexin terminals in the locus coeruleus
Keywords: GABA; PSD-95; rat; synaptophysin; VGluT; VGAT; Cy2; cyanine; Cy3; indocarbocyanine; Cy5; indodicarbocyanine; Dky; donkey; Glu; glutamate; GP; guinea-pig; Gt; goat; LC; locus coeruleus; LDCVs; large dense core vesicles; Ms; mouse monoclonal; NDS; normal do
Intranasal delivery of insulin and a nitric oxide synthase inhibitor in an experimental model of amyotrophic lateral sclerosis
Keywords: amyotrophic lateral sclerosis; insulin; free oxygen radicals; endplate innervation; behavior testing; electrophysiology; ALS; amyotrophic lateral sclerosis; ChAT; choline acetyltransferase; CMAP; compound motor action potential; CREB; cAMP response elemen