Keywords: تین کیناز 1; Pattern-recognition receptors (PRRs); Toll-like receptors (TLRs); RIG-I-like receptors (RLRs); NOD-like receptors (NLRs); Small molecule modulators; BIR; baculovirus inhibitor repeat; CARD; caspase recruitment domains; CFS; chronic fatigue syndrome; CLR;
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Keywords: تین کیناز 1; ABIN; A20 binding and inhibitor of NF-κB; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; Atg; autophagy-related gene; C9ORF72; chromosome 9 open reading frame 72; CC; coiled-coil; cIAP; cellular inhibitor of apoptosis protein; CYLD; cylin
Keywords: تین کیناز 1; Clarithromycin (PubChem CID: 84029); poly I:C (PubChem CID: 32744); Pam3CSK4 (PubChem CID: 130704); CAM; clarithromycin; CARD; caspase activation and recruitment domain; CCL5; chemokine (C-C motif) ligand 5; CF; cystic fibrosis; COPD; chronic obstructive
Keywords: تین کیناز 1; APAP; acetaminophen; ALD; alcoholic liver disease; BAG4; Bcl2-associated athanogene 4; CCCP; carbonyl-cyanide m-chlorophenyl hydrazine; Clec16a; c-type lectin domain family 16, member A; Dfcp1; double FYVE-containing protein 1; DUB; deubiquitinating enzym
Keywords: تین کیناز 1; ACP5; Acid phosphatase 5; ADAR1; Adenosine deaminase RNA-specific 1; AGS; Aicardi-Goutières syndrome; ALRs; AIM2-like receptors; AIM2; Absent in melanoma 2; ASC; Apoptosis-associated speck-like protein containing a CARD; CANDLE; Chronic atypical neutroph
Keywords: تین کیناز 1; ACOX-1; acyl-CoA oxidase 1; AdipoQ; adiponectin; BCE; black currant extract; CD68; cluster of differentiation 68; CLS; crown-like structures; CTP-1; carnitine palmotyoltransferase 1; CVD; cardiovascular disease; DIO; diet-induced obesity; FAS; fatty acid
Keywords: تین کیناز 1; AIM2; absent in melanoma 2; AP-1; activating protein-1; APOBEC; apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like; AZT; azidothymidine; CCCR5; C-C chemokine receptor type 5; CDK1; cyclin-dependent kinase 1; CXCR4; C-X-C chemokine receptor t
Keywords: تین کیناز 1; AP-1; jun proto-oncogene; BAI3; brain-specific angiogenesis inhibitor 3; CADM2; cell adhesion molecule 2; CAGE; cap analysis of gene expression; cDNA; DNA complementary to RNA; ChIP; chromatin immunoprecipitation; FGF14; fibroblast growth factor 14; GADD4
Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies
Keywords: تین کیناز 1; NF-κB; nuclear factor kappa B; AP-1; activator protein; STAT3; signal transducer and activator of transcription 3; NK cells; natural killer cells; TNF-α; tumor necrosis factor-α; NO; nitric oxide; iNOS; inducible nitric oxygen synthase; ROS; reactive o
Promising new therapeutic targets for regulation of inflammation and immunity: RING-type E3 ubiquitin ligases
Keywords: تین کیناز 1; ALS; amyotrophiclateral sclerosis; AP-1; activator protein 1; APC; antigen-presenting cell; APC/C; anaphase promoting complex/cyclosome; CLR; C-type lectin receptor; CRL; Cullin RING ligase; ERK; extracellular signalregulated kinase; FANC; Fanconi anemia
IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease
Keywords: تین کیناز 1; Asthma; house dust mite; glycolysis; IL-1; inhibitor of κB kinase ε; lactate; lactate dehydrogenase A; AHR; Airways hyperresponsiveness; BAL; Bronchoalveolar lavage; BMI; Body mass index; DC; Dendritic cell; 2-DG; 2-Deoxyglucose; ECAR; Extracellular aci
Optineurin Insufficiency Disbalances Proinflammatory and Anti-inflammatory Factors by Reducing Microglial IFN-β Responses
Keywords: تین کیناز 1; ALS; amyotrophic lateral sclerosis; BMDM; bone marrow-derived macrophages; C9orf72; chromosome 9 open-reading frame 72; CNS; central nervous system; CXCL; CXC chemokine ligand; DAMPs; damage-associated molecular patterns; DMEM; Dulbecco's Modified Eagle
Ca2+ signaling and Src-kinases-controlled cellular functions
Keywords: تین کیناز 1; Ca2+ channels; Cell signaling; Phosphatases; Receptors; Src-family kinases; A23187; 5-(methylamino)-2-({(2R,3R,6S,8S,9R,11R)-3,9,11-trimethyl-8-[(1S)-1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl]-1,7-dioxaspiro[5.5]undec-2-yl}methyl)-1,3-benzoxazole-4-carboxyli
Ginsenoside Rc from Panax ginseng exerts anti-inflammatory activity by targeting TANK-binding kinase 1/interferon regulatory factor-3 and p38/ATF-2
Keywords: تین کیناز 1; anti-inflammatory activity; ginsenoside Rc; p38; Panax ginseng; TANK-binding kinase 1;
Human B cells fail to secrete type I interferons upon cytoplasmic DNA exposure
Keywords: تین کیناز 1; IFN I; type I interferon(s); IFI16; interferon-inducible protein 16; cGAMP; cyclic GMP-AMP; cGAS; cGAMP synthase; STING; stimulator of interferon genes; TBK1; TANK-binding kinase 1; IRF3; interferon regulatory factor 3; ISG; interferon-stimulated genes; P
The anticancer functions of RIG-I-like receptors, RIG-I and MDA5, and their applications in cancer therapy
Keywords: تین کیناز 1; 5â²PP; 5â²-diphosphate; 5â²ppp; 5â²triphosphorylated; Bcl2; B-cell lymphoma-2; BIRC3; baculoviral IAP repeat-containing 3; CARDs; caspase activation and recruitment domains; CRC; colorectal cancer; CTD; C-terminal domain; CTLs; cytotoxic T lymphocytes
Zebrafish STAT6 negatively regulates IFNÏ1 production by attenuating the kinase activity of TANK-binding kinase 1
Keywords: تین کیناز 1; STAT6; Negative regulator; Interferon; TBK1; Zebrafish; CIP; calf intestinal phosphatase; CPE; cytopathic effect; EPC; epithelioma papulosum cyprini; GAS; interferon gamma activated sequence; IFN; interferon; IRF; IFN regulatory factor; IRF3; interferon r
Mutational analysis of TBK1 in Taiwanese patients with amyotrophic lateral sclerosis
Keywords: تین کیناز 1; Amyotrophic lateral sclerosis; ALS; TBK1; TANK-Binding kinase 1;
Gene expression profiling reveals the role of RIG1 like receptor signaling in p53 dependent apoptosis induced by PUVA in keratinocytes
Keywords: تین کیناز 1; PUVA; 8-methoxypsoralen plus UVA; RIG-1; retinoic acid induced gene 1; MDA5; melanoma differentiation associated gene 5; MAVS; mitochondrial antiviral signaling protein; TBK; TANK-binding kinase 1; IKKε; inhibitor of kappaB kinase epsilon; IRF3; interfer
Yersinia YopJ negatively regulates IRF3-mediated antibacterial response through disruption of STING-mediated cytosolic DNA signaling
Keywords: تین کیناز 1; BMDMs; bone marrow-derived macrophages; c-di-GMP; cyclic diguanylate monophosphate; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic reticulum; FBS; fetal bovine serum; GST; Glutathione S-transferase; HEK293T; human embryonic kidney; IB; immunobl
Functions of the two zebrafish MAVS variants are opposite in the induction of IFN1 by targeting IRF7
Keywords: تین کیناز 1; MAVS variants; Negative regulator; Interferon; IRF7; Zebrafish; CARD; caspase recruiting domain; CPE; cytopathic effect; DBD; DNA binding domain; EPC; epithelioma papulosum cyprini; GBP4; guanylate binding protein 4; IFN; interferon; IKKε; IkappaB kinase
Identification of a novel MYOC mutation, p.(Trp373*), in a family with open angle glaucoma
Keywords: تین کیناز 1; ANZRAG; Australian and New Zealand Registry of Advanced Glaucoma; BCVA; best corrected visual acuity; IOP; intraocular pressure; LE; left eye; mRNA; messenger RNA; MYOC; myocilin; NATA; National Association of Testing Authorities; NMD; nonsense mediated d
Toll like receptors in self-recovering hepatitis E patients with or without pregnancy
Keywords: تین کیناز 1; ANC; Antenatal care (pregnancy); HEV; hepatitis E virus; TLR; Toll like receptors; IRAK; interleukin-1 receptor-associated kinase; IkBα; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; NFkB; nuclear factor kappa-light
Combined CpG and poly I:C stimulation of monocytes results in unique signaling activation not observed with the individual ligands
Keywords: تین کیناز 1; TLRs; Toll-like receptors; CpG; unmethylated CpG oligodeoxynucleotides; poly I:C; polyinosinic-polycytidylic acid; NO; nitric oxide; iNOS; inducible nitric oxide synthase; CREB; cAMP response element-binding protein; NFκB; nuclear factor κB; PRRs; pat
Dysregulated TLR3-dependent signaling and innate immune activation in superoxide-deficient macrophages from nonobese diabetic mice
Keywords: تین کیناز 1; ROS; reactive oxygen species; T1D; type 1 diabetes; NOD; nonobese diabetic; BM-MÏ; bone marrow-derived macrophages; MHC; major histocompatibility complex; NOX; NADPH oxidase; Ncf1; neutrophil cytosolic factor 1; TLR; Toll-like receptor; poly(I:C); polyin
ESPRIT: An automated, library-based method for mapping and soluble expression of protein domains from challenging targets
Keywords: تین کیناز 1; ESPRIT; expression of soluble proteins by random incremental truncation; GFP; green fluorescent protein; TBK1; TANK-binding kinase 1; IPTG; isopropyl-beta-d-thiogalactopyranoside; TEV; tobacco etch virus; BCCP; biotin carboxyl carrier protein.; ESPRIT; NF
Oncolytic viruses as experimental treatments for malignant gliomas: Using a scourge to treat a devil
Keywords: تین کیناز 1; AdV; Adenovirus; APC; antigen-presenting cell; BBB; blood-brain barrier; CED; convection-enhanced delivery; CNS; central nervous system; ECM; extracellular matrix; FasL; Fas ligand; GALV; gibbon ape leukemia virus; GBM; glioblastoma mulitforme; GIM; gli
Cationic lipids activate cellular cascades. Which receptors are involved?
Keywords: تین کیناز 1; AP-1; activator protein 1; CD 14/80/86; cluster of differentiation 14/80/86; diC14-amidine; N-t-butyl-Nâ²-tetradecyl-3-tetradecylaminopropionamidine; DAG; diacylglycerol; DMPC; dimyristoyl-phosphatidylcholine; DMPG; dimyristoyl-phosphatidylglycerol; DMKD