دانلود مقالات ISI درباره Tgfβ + ترجمه فارسی

Pharmacotherapies for Retinal Detachment

Keywords: AIF; apoptosis-inducing factor; Faim2; Fas apoptotic inhibitory molecule 2; FDA; US Food and Drug Administration; MCP-1; monocyte chemoattractant protein-1; mTOR; mammalian target of rapamycin; PDGF; platelet-derived growth factor; PDGFRα; platelet-deri

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Inhibition of TGFβ cell signaling for limbal explant culture in serumless, defined xeno-free conditions

Keywords: Limbal epithelium; Explant culture; TGFβ; SB431542; A83-01; Xeno-free explants culture;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Regulation of the ErbB network by the MIG6 feedback loop in physiology, tumor suppression and responses to oncogene-targeted therapeutics

Keywords: RTK; receptor tyrosine kinase; EGF; epidermal growh factor; EGFR; epidermal growth factor receptor; LRIG1; leucin-rich repeats and immunoglobulin-like domains1; MIG; 6mitogen inducible gene 6; RALT; receptor associated late transducer; ERRFI1; ErbB recept

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Common pathways regulate Type III TGFβ receptor-dependent cell invasion in epicardial and endocardial cells

Keywords: βArr2; beta-arrestin2; ALK; activin receptor-like kinases; AV; atrioventricular; BMP; bone morphogenetic protein; ca; constitutively active; EMT; Epithelial-Mesenchymal Transformation; FGF; fibroblast growth factor; GFP; green fluorescent protein; GIPC

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Thrombospondin-1 promotes mesenchymal stromal cell functions via TGFβ and in cooperation with PDGF

Keywords: Thrombospondin-1; Mesenchymal stromal cells; TGFβ; PDGF; Matricellular proteins;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Original Full Length ArticleInhibition of TGFβ signaling decreases osteogenic differentiation of fibrodysplasia ossificans progressiva fibroblasts in a novel in vitro model of the disease

Keywords: FOP; fibrodysplasia ossificans progressiva; FCS; fetal calf serum; BMP; bone morphogenetic protein; TGFβ; transforming growth factor β; Runx2; runt-related transcription factor 2; Alp; alkaline phosphatase; OC; osteocalcin; ACVR1; activin receptor IA; A

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

A dual prognostic role for the TGFβ receptors in human breast cancer

Keywords: TGFβ; Breast cancer; Prognosis; Molecular subtypes; TGFβ receptors; Patient outcomes;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Shoc2-tranduced ERK1/2 motility signals - Novel insights from functional genomics

Keywords: EGF; epidermal growth factor; ERK1/2; extracellular signal-regulated kinase 1 and 2; KSR1; kinase suppressor of Ras (KSR1); MP1; mitogen-activated protein 1; PNGase F; Peptide-N-Glycosidase F; Endo H; Endoglycosidase H; PP1c; protein phosphatase 1c; qPCR;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Pro-fibrotic effects of PFKFB4-mediated glycolytic reprogramming in fibrous dysplasia

Keywords: Fibrous dysplasia; hiPSCs; Bone sphere; TGFβ; Glycolytic reprogramming;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

M10, a caspase cleavage product of the hepatocyte growth factor receptor, interacts with Smad2 and demonstrates antifibrotic properties in vitro and in vivo

Keywords: HGF; Hepatocyte growth factor; c-MET, MET; mesenchymal-epithelial transition factor; systemic sclerosis, SSc; scleroderma; ILD; interstitial lung disease; IPF; idiopathic pulmonary fibrosis; TGFβ; transforming growth factor beta; PLC; phospholipase C; PK

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

TGFβ regulates Galectin-3 expression through canonical Smad3 signaling pathway in nucleus pulposus cells: implications in intervertebral disc degeneration

Keywords: Intervertebral disc; Nucleus pulposus; Galectin-3; TGFβ; Smad3; Disc degeneration;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

BMP1-like proteinases are essential to the structure and wound healing of skin

Keywords: BMP1; bone morphogenetic protein 1; mTLL1; mammalian tolloid-like 1; OI; osteogenesis imperfecta; BTP; bone morphogenetic protein 1/tolloid-like proteinase; ECM; extracellular matrix; SLRP; small leucine-rich proteoglycan; TGFβ; transforming growth facto

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Cerulein-induced pancreatic fibrosis is modulated by Smad7, the major negative regulator of transforming growth factor-β signaling

Keywords: Smad7; TGFβ; Chronic pancreatitis; Fibrosis;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2016 سفارش ترجمه

Fibroblast activation protein-α, a stromal cell surface protease, shapes key features of cancer associated fibroblasts through proteome and degradome alterations

Keywords: FAPα; CAFs; Secretome; Degradome; Angiogenesis; TGFβ;

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2016 سفارش ترجمه

Microfluidic devices for the study of actin cytoskeleton in constricted environments: Evidence for podosome formation in endothelial cells exposed to a confined slit

Keywords: PDMS; polydimethylsiloxane; RIE; reactive-ion etching; ICP; inductively coupled plasma; EGFP; enhanced green fluorescence protein; FN; fibronectin; TGFβ; transforming growth factor beta; IRM; interference reflection microscopy; DIC; differential interfer

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

The cytoprotective effect of biglycan core protein involves Toll-like receptor 4 signaling in cardiomyocytes

Keywords: TLR4; Toll-like receptor 4; SI/R; simulated ischemia/reperfusion injury; rhBGNc; recombinant human biglycan core protein; GAG; glycosaminoglycan; TGFβ; transforming growth factor-beta; BSA; bovine serum albumin; D-PBS; Dulbecco's phosphate-buffered salin

دانلود رایگان متن کامل مقاله ISI 31 صفحه سال انتشار : 2016 سفارش ترجمه

Epithelial Transforming Growth Factor-β Signaling Does Not Contribute to Liver Fibrosis but Protects Mice From Cholangiocarcinoma

Keywords: TGFβ; Signal Transduction; Mouse Model; Liver Cancer; α-SMA; α-smooth muscle actin; BDL; bile duct ligation; DDC; 3,5-diethoxycarbonyl-1,4-dihydro-collidin; DEN; diethylnitrosamine; HCC; hepatocellular carcinoma; HSC; hepatic stellate cell; mRNA; messe

دانلود رایگان متن کامل مقاله ISI 34 صفحه سال انتشار : 2016 سفارش ترجمه

Aryl Hydrocarbon Receptor Ligands in Cigarette Smoke Induce Production of Interleukin-22 to Promote Pancreatic Fibrosis in Models of Chronic Pancreatitis

Keywords: TCDD; BaP; Immune Regulation; PSC; CP; AhR; aryl hydrocarbon receptor; αSMA; α−smooth muscle actin; BaP; benzo[a]pyrene; BM; bone marrow; CP; chronic pancreatitis; ECM; extracellular matrix; IL; interleukin; LPS; lipopolysaccharide; PSC; pancreatic st

دانلود رایگان متن کامل مقاله ISI 38 صفحه سال انتشار : 2016 سفارش ترجمه

Notch and TGFβ form a positive regulatory loop and regulate EMT in epithelial ovarian cancer cells

Keywords: Epithelial ovarian cancer; Notch; TGFβ; EMT;

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Effect of MTHFR, TGFβ1, and TNFB polymorphisms on osteoporosis in rheumatoid arthritis patients

Keywords: ACR; American College of Rheumatology; BMD; bone mineral density; CI; confidence interval; LTA; lymphotoxin alpha; MHC; major histocompatibility complex; MTHFR; methylene tetrahydrofolate reductase; OR; odds ratio; OP; osteoporosis; χ2; Pearson chi squar

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney

Keywords: ABCC6; ATP-binding cassette, subfamily C, member 6; BAEC; bovine aortic endothelial cells; BMPs; bone morphogenetic proteins; MGP; matrix Gla protein; PXE; pseudoxanthoma elasticum; TGFβ; transforming growth factor beta; ATP-binding cassette sub-family C

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2015 سفارش ترجمه

Negative regulation of TGFβ-induced lens epithelial to mesenchymal transition (EMT) by RTK antagonists

Keywords: TGFβ; Lens pathology; EMT; RTK antagonists; Spry; Sef; Spred;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

CTGF/CCN2 exerts profibrotic action in myoblasts via the up-regulation of sphingosine kinase-1/S1P3 signaling axis: Implications in the action mechanism of TGFβ

Keywords: CTGF; connective tissue growth factor; TGFβ; transforming growth factor beta; SK; sphingosine kinase; S1P; sphingosine 1-phosphate; α-SMA; α-smooth muscle actin; DMEM; Dulbecco's modified Eagle's medium; DPBS; Dulbecco's modified phosphate-buffered sal

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Blockage of TGFβ-SMAD2 by demethylation-activated miR-148a is involved in caffeic acid-induced inhibition of cancer stem cell-like properties in vitro and in vivo

Keywords: CaA; 3,4-dihydroxycinnamic acid; CSCs; cancer stem cells; DNMT; DNA methyltransferases; HCC; hepatocellular carcinoma; miR-148a; microRNA-148a; qMSP; quantitative methylation-specific polymerase chain reaction; SAM; S-adenosylmethionine; TGFβ; transformi

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Functional interaction between COL4A1/COL4A2 and SMAD3 risk loci for coronary artery disease

Keywords: TGFβ; SMAD3; COL4A1; COL4A2; Type IV collagen; Coronary artery disease; Atherosclerosis; Epistasis; AoSMCs; primary aortic smooth muscle cells; CAD; coronary artery disease; GWAS; genome-wide association study; LD; linkage disequilibrium; qRT-PCR; quanti

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Epigenetic control of EMT/MET dynamics: HNF4α impacts DNMT3s through miRs-29

Keywords: ChIP; chromatin immunoprecipitation; DNMT; DNA methyltransferase; EMT; epithelial to mesenchymal transition; MET; mesenchymal to epithelial transition; TGFβ; transforming growth factor β; HNF4α; hepatocyte nuclear factor 4 alpha; qPCR; real-time polyme

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

TGFβ functionalized starPEG-heparin hydrogels modulate human dermal fibroblast growth and differentiation

Keywords: 2D; two dimensional; 3D; three dimensional; αSMA; alpha smooth muscle actin; CL; MMP-cleavable linker; dFb; dermal fibroblast; ECM; extracellular matrix; Hep; heparin; MFb; myofibroblast; MMP; metalloprotease; PDGF; platelet derived growth factor; PEG; p

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

NOTCH1 regulates matrix gla protein and calcification gene networks in human valve endothelium

Keywords: CAVD; calcific aortic valve disease; ALP; alkaline phosphatase; IBSP; bone sialoprotein; SPARC; osteonectin; TGFβ; transforming growth factor beta; WNT; wingless-type MMTV integration site family; CSL; suppressor of hairless; MAML; mastermind-like protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Fingolimod induces the transition to a nerve regeneration promoting Schwann cell phenotype

Keywords: Akt; PKB, protein kinase B; BDNF; brain derived neurotrophic factor; cAMP; cyclic adenosine monophosphate; CIDP; chronic inflammatory demyelinating polyneuropathy; CNS; central nervous system; Cx32; connexin-32; DMSO; dimethyl sulfoxide; DRG; dorsal root

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of microRNA-21 by TALEN leads to diminished cell transformation and increased expression of cell-environment interaction genes

Keywords: TALEN; transcription activator-like effectors nuclease; miR-21; microRNA-21; TGFβ; transforming growth factor beta; RNA-Seq; next-generation shotgun RNA sequencing; microRNA; miR-21; TALEN; gene editing; cancer; extracellular matrix;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

LIM homeobox transcription factor Lhx2 inhibits skeletal muscle differentiation in part via transcriptional activation of Msx1 and Msx2

Keywords: ES cells; embryonic stem cells; DMEM; Dulbecco׳s modified Eagle׳s medium; FBS; fetal bovine serum; PS; penicillin-streptomycin; FGF-2; fibroblast growth factor-2; RT-PCR; reverse transcription PCR; Gapdh; glyceraldehyde 3-phosphate dehydrogenase; PBS; p

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

The BRAFV600E inhibitor, PLX4032, increases type I collagen synthesis in melanoma cells

Keywords: Vemurafenib; TGFβ; pERK; IL-8; MMP-1; Human melanoma; Murine melanoma;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Transforming Growth Factor β Signaling in Colorectal Cancer Cells With Microsatellite Instability Despite Biallelic Mutations in TGFBR2

Keywords: Colon Cancer; Signal Transduction; Tumor Suppressor; RNA Editing; A10; 10 adenines microsatellite; cDNA; complementary DNA; CRC; colorectal cancer; MSI-H; microsatellite instability-high; p-SMAD2; phosphorylated SMAD2 protein; PCR; polymerase chain reacti

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2015 سفارش ترجمه

Identification of a PEAK1/ZEB1 signaling axis during TGFβ/fibronectin-induced EMT in breast cancer

Keywords: TGFβ; EMT; PEAK1 kinase; Cancer metastasis; Breast cancer;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2015 سفارش ترجمه

The microfibril-associated glycoproteins (MAGPs) and the microfibrillar niche

Keywords: BAT; brown adipose tissue; BSw; black Swiss; DEXA; longitudinal dual energy X-ray absorptiometry; ECM; extracellular matrix; EGF; epidermal growth factor; LTBP; latent TGFβ binding protein; MAGP; microfibril-associated glycoprotein; Ma; million years; TG

دانلود رایگان متن کامل مقاله ISI 21 صفحه سال انتشار : 2015 سفارش ترجمه

Fibroblast heterogeneity and its implications for engineering organotypic skin models in vitro

Keywords: Organotypic skin; Fibroblast heterogeneity; Wound healing; Skin models; Skin substitutes; Tissue engineering; 3D; three-dimensional; AdSCs; adipose-derived stem cells; AP-1; activated protein-1; Blimp1; B lymphocyte-induced maturation protein-1; BP; bullo

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Hsp90/Cdc37 assembly modulates TGFβ receptor-II to act as a profibrotic regulator of TGFβ signaling during cardiac hypertrophy

Keywords: Hsp90; Heat shock protein 90; Cdc37; Cell division cycle 37; AngII; Angiotensin II; TGFβ; Transforming growth factor β; ECM; Extracellular matrix; TβR-I; Transforming growth factor β receptor-I; TβR-II; Transforming growth factor β receptor-II; 17AA

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2015 سفارش ترجمه

Targeting the TGFβ pathway for cancer therapy

Keywords: Angiogenesis; Fibrosis; Metastasis; Microenvironment; TGFβ inhibitors; Tumor-stroma interactions; bFGF; basic fibroblast growth factor; bi-shRNAi; bi-functional short hairpin RNAi; CAF; cancer-associated fibroblasts; CR; complete response; CTGF; connecti

دانلود رایگان متن کامل مقاله ISI 46 صفحه سال انتشار : 2015 سفارش ترجمه

Clinical Application of Basic ScienceStellate cells and the development of liver cancer: Therapeutic potential of targeting the stroma

Keywords: HCC; hepatocellular carcinoma; ICC; intrahepatic cholangiocarcinoma; HSC; hepatic stellate cell; ECM; extracellular matrix; TGFβ; transforming growth factor beta; MMP; matrix metallopeptidase; EMT; epithelial to mesenchymal cell transition; PDGF; platele

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2014 سفارش ترجمه

Role of Flightless-I (Drosophila) homolog in the transcription activation of type I collagen gene mediated by transforming growth factor beta

Keywords: SWI/SNF complex; Chromatin remodeling; TGFβ; FLII;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Losartan inhibits endothelial-to-mesenchymal transformation in mitral valve endothelial cells by blocking transforming growth factor-β-induced phosphorylation of ERK

Keywords: VEC; valve endothelial cells; EndMT; endothelial to mesenchymal transformation; TGFβ; transforming growth factor-β; CAEC; carotid artery endothelial cells; α-SMA; α-smooth muscle actin; AT1; angiotensin II type 1 receptor; AT2; angiotensin II type 2 r

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2014 سفارش ترجمه

Dose-dependent Nodal/Smad signals pattern the early mouse embryo

Keywords: TGFβ; Nodal; Gastrulation; Smad2/3; Epiblast;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular characterization of gdf9 and bmp15 genes in rare minnow Gobiocypris rarus and their expression upon bisphenol A exposure in adult females

Keywords: actb; actin beta; Af; atretic follicle; AR; androgen receptor; AHR; aryl hydrocarbon receptor; BPA; bisphenol A; Bmp15; bone morphogenetic protein 15; Coc; cortical alveolus oocytes; KL; c-Kit ligand; dpf; days post-fertilization; DMSO; dimethyl sulfoxide

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Betaglycan blocks metastatic behaviors in human granulosa cell tumors by suppressing NFκB-mediated induction of MMP2

Keywords: AGCT; adult-type granulosa cell tumor; ECM; extracellular matrix; GCT; granulosa cell tumors; MMPs; matrix metalloproteinases; NFκB; nuclear factor kappa-B; qRT-PCR; quantitative real-time reverse transcriptase PCR; SFM; serum-free media; TGFβ; transfor

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

To BMP or not to BMP during vertebrate limb bud development

Keywords: Antagonist; BMP; Limb bud; Mouse; Signaling; TGFβ;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Halofuginone improves muscle-cell survival in muscular dystrophies

Keywords: CMD; congenital MD; DMD; Duchenne MD; ECM; extracellular matrix; ERK; extracellular signal-regulated protein kinase; DAPI; 4′,6-diamidino-2-phenylindole; MAPK; mitogen-activated protein kinase; MDs; muscular dystrophies; PI3K; phosphoinositide 3 kinase;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Ionizing radiation-inducible miR-494 promotes glioma cell invasion through EGFR stabilization by targeting p190B RhoGAP

Keywords: ECM; extracellular matrix; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor (EGFR); FACS; fluorescence-activated cell sorting; FBS; fetal bovine serum; GAP; GTPase activating protein; GEF; guanine nucleotide exchange factor; IR; ionizi

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Extracellular vesicle-mediated transfer of long non-coding RNA ROR modulates chemosensitivity in human hepatocellular cancer

Keywords: EV; extracellular vesicle; HCC; hepatocellular carcinoma; miRNA; microRNA; VD; vesicle-depleted; lncRNA; long non-coding RNA; linc-ROR; long intergenic non-coding RNA; TGFβ; transforming growth factor β; CT; cycle threshold; siRNA; small interfering RNA

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Myofibroblasts: Trust your heart and let fate decide

Keywords: Fibrosis; Extracellular matrix; TGFβ; Angiotensin II; Serum response factor; TRP channel;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Identification of potent antagonist antibodies against mouse IL-13Rα1 using novel bioassays

Keywords: CCL; CC chemokine ligand; IL; interleukin; IL-4Rα; interleukin-4 receptor α; IL-13Rα1; interleukin-13 receptor α1; IL-13Rα2; interleukin-13 receptor α2; mAb; monoclonal antibody; HRP; horseradish peroxidase; FBS; fetal bovine serum; PBS; phosphate-b

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه