Separation of human CD4+CD39+ T cells by magnetic beads reveals two phenotypically and functionally different subsets
Keywords: Adenosine; Cancer; CD39; CD73; FOXP3; Treg
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Heat shock protein gp96 enhances humoral and T cell responses, decreases Treg frequency and potentiates the anti-HBV activity in BALB/c and transgenic mice
Keywords: Hepatitis B virus; gp96; HBcAg; HBsAg; Treg; HBV transgenic mice; Anti-HBV;
Moving to tolerance: Clinical application of T regulatory cells
Keywords: APC; antigen presenting cell; ATG; anti thymocyte globulin; aTreg; adaptive T regulatory cell; AZT; 3â²-azido-3â²-deoxythymidine; CNI; calcineurin inhibitor; CyA; cyclosporin A; DC; dendiric cell; DST; donor specific transfusion; GVHD; graft versus host
Research ArticleHepatitis C virus induces the expression of CCL17 and CCL22 chemokines that attract regulatory T cells to the site of infection
Keywords: HCV; hepatitis C virus; IFN; interferon; Treg; regulatory T cells; CHC; chronic hepatitis C; PBMC; peripheral blood mononuclear cells; MDDC; monocyte-derived dendritic cells; SVR; sustained virological response; RT-PCR; reverse transcription-polymerase ch
Regulation of the immune response and inflammation by histamine and histamine receptors
Keywords: Histamine receptor; innate immunity; adaptive immunity; immune regulation; G protein-coupled receptor; review; cAMP; Cyclic adenosine monophosphate; DC; Dendritic cell; EPAC; Exchange protein directly activated by cyclic adenosine monophosphate 1; Foxp3
Neuroantigen-specific CD8+ regulatory T-cell function is deficient during acute exacerbation of multiple sclerosis
Keywords: Multiple sclerosis; CD8; Treg; Immune regulation; Exacerbation; Suppressor
Intestinal Inflammation and Cancer
Keywords: IBD; Intestine; Neoplasia; Animal Model; Innate Immunity; Adaptive Immunity; APC; adenomatous polyposis coli; AOM; azoxymethane; CRC; colorectal cancer; DSS; dextran sodium sulfate; GPX; glutathione peroxidase; IL; interleukin; MSI; microsatellite instabi
Making sense of regulatory T cell suppressive function
Keywords: APC; antigen presenting cells; BM; bone marrow; BMT; bone-marrow transplantation; cAMP; cyclic AMP; CTL; cytotoxic T lymphocytes; CTLA-4; cytotoxic T-lymphocyte antigen 4; DC; dendritic cells; DN; double negative Treg cells; EAE; experimental autoimmune e
Lymphocytes in neuroprotection, cognition and emotion: Is intolerance really the answer?
Keywords: Neuroprotection; Autoimmunity; Treg; Immunoregulation; IL-10;
Growth factor independence 1 (Gfi1) as a regulator of lymphocyte development and activation
Keywords: Gfi1; Mouse; B-cell development; T-cell development; Il-7R; Transcription factor; CD4; CD8; Th2; Treg; Th17
Retinoic Acid Attenuates Ileitis by Restoring the Balance Between T-Helper 17 and T Regulatory Cells
Keywords: Inflammation; Immune Response; Inflammatory Bowel Disease; Tolerance; ÎARE; ÎAU-rich element; DC; dendritic cell; FoxP3; forkhead box P3; IEC; intestinal epithelial cell; IL; interleukin; LP; lamina propria; MLN; mesenteric lymph node; PCR; polymerase c
Epigallocatechin-3-gallate prevents lupus nephritis development in mice via enhancing the Nrf2 antioxidant pathway and inhibiting NLRP3 inflammasome activation
Keywords: BUN; blood urea nitrogen; Cr; creatinine; DHE; dihydroethidium; EGCG; epigallocatechin-3-gallate; ELISA; enzyme-linked immunosorbent assay; GPx; glutathione peroxidase; IHC; immunohistochemistry; IL; interleukin; NF-κB; nuclear factor-kappa B; NLR; NOD-l
Human T cells induce their own regulation through activation of B cells
Keywords: Regulatory B cells; T-cell response; IL-10; Regulatory T cells; Autoimmune disease; Systemic lupus erythematosus; Breg; B regulatory cell; EAE; experimental autoimmune encephalomyelitis; MFI; mean fluorescence intensity; PC7; PE-linked to cyanin 7; pSS; p
Effector T cells in rheumatoid arthritis: Lessons from animal models
Keywords: Rheumatoid arthritis; T cell; TH1; TH17; Treg; Animal model;
Nasal cardiac myosin peptide treatment and OX40 blockade protect mice from acute and chronic virally-induced myocarditis
Keywords: Autoimmune myocarditis; IL-10; Treg; Cardiac myosin; Peptide therapy; Coxsackie virus B3; OX40;
Interferon-λ Mediates Oral Tolerance and Inhibits Antigen-Specific, T-Helper 2 Cell-Mediated Inflammation in Mouse Intestine
Keywords: Food Allergy; Immune Response; Mucosal Immunity; Treg Cells; ALDH; aldehyde dehydrogenase; BmDC; bone marrow-derived dendritic cell; CFSE; carboxyfluorescein succinimidyl ester; DC; dendritic cell; FACS; fluorescence-activated cell sorter; IFN; interfer
Dendritic Cells Prevent Rather Than Promote Immunity Conferred by a Helicobacter Vaccine Using a Mycobacterial Adjuvant
Keywords: Gastric Cancer; Bacteria; Ulcer; Gastric Adenocarcinoma; APC; allophycocyanin; CT; cholera toxin; DC; dendritic cell; DT; diphtheria toxin; IFN-γ; interferon-γ; IL; interleukin; IP; intraperitoneal; MHC; major histocompatibility complex; MLN; mesenteric
Tolerogenic dendritic cells and their role in transplantation
Keywords: APC; antigen-presenting cell; BM; bone marrow; mDC; myeloid dendritic cell; pDC; plasmacytoid dendritic cell; Treg; regulatory T cell; tol DC; tolerogenic dendritic cell; Dendritic cells; Antigen presentation; T cells; T regulatory cells; Tolerance; Trans
Inflammation Promotes the Loss of Adeno-Associated Virus-Mediated Transgene Expression in Mouse Liver
Keywords: Hepatic Gene Therapy; Loss of Tolerance; Immune Response; Liver Inflammation; AAT; α1-antitrypsin; AAV; adeno-associated vector; Ad; adenovirus vector; β-gal; β-galactosidase; CTL; cytotoxic T lymphocyte; GFP; green fluorescent protein; IFN; interferon
The Chemokine Receptor CCR9 Is Required for the T-Cell-Mediated Regulation of Chronic Ileitis in Mice
Keywords: CD; Regulatory T Cells; Inflammation; Immune System; CCR9; chemokine receptor 9; CCL25; chemokine ligand 25; FoxP3; forkhead box P3; LP; lamina propria; mAb; monoclonal antibody; MLN; mesenteric lymph node; TNFÎARE; tumor necrosis factor Îadenosine urac
Wasp venom immunotherapy induces activation and homing of CD4+CD25+ forkhead box protein 3-positive regulatory TÂ cells controlling TH1 responses
Keywords: Immunotherapy; lymph node; regulatory T cell; tolerance; wasp venom; Foxp3; Forkhead box protein 3; Treg; Regulatory T; TT; Tetanus toxoid; VIT; Venom immunotherapy;
Vascular CD39/ENTPD1 Directly Promotes Tumor Cell Growth by Scavenging Extracellular Adenosine Triphosphate
Keywords: ATP; adenosine triphosphate; ADP; adenosine diphosphate; AMP; adenosine monophosphate; ENTPD1; ectonucleoside triphosphate diphosphohydrolase 1; LSEC; liver sinusoidal endothelial cell; Treg; regulatory T cells; TLC; thin-layer chromatography; wt; wild ty
Antigen-Presenting Cell Production of IL-10 Inhibits T-Helper 1 and 17 Cell Responses and Suppresses Colitis in Mice
Keywords: Mouse Model; Inflammatory Bowel Disease; Immune Response; Microbiota; APC; antigen-presenting cell; CBL; cecal bacterial lysate; DC; dendritic cell; ELISA; enzyme-linked immunosorbent assay; FoxP3; forkhead box P3; GF; germ-free; IFN; interferon; IL; inte
Cytokines et différenciation lymphocytaire T au cours de la sclérodermie systémique
Keywords: Sclérodermie systémique; Cytokine; Immunologie; Th1; Th2; Th9; Th17; Th22; Treg; Cellules T régulatrices; Lymphocyte; Différenciation lymphocytaire; PhysiopathologieSystemic sclerosis; Cytokine; Immunology; Th1; Th2; Th9; Th17; Th22; Treg; T regulatory ce
Mycobacterium bovis Bacillus Calmette-Guérin Killed by Extended Freeze-Drying Reduces Colitis in Mice
Keywords: Killed BCG; IL-10; Therapeutic Vaccine; Immune Regulation; BCG; Bacillus Calmette-Guérin; DSS; dextran sodium sulfate; EFD; extended freeze-dried; IFN; interferon; IL; interleukin; MLN; mesenteric lymph node; MPO; myeloperoxidase; NF-κB; nuclear facto
Immunologic Basis of Graft Rejection and Tolerance Following Transplantation of Liver or Other Solid Organs
Keywords: Regulatory T Cells; Operational Tolerance; Costimulation Blockade; Immunosuppression Weaning; Ab; antibody; APC; antigen-presenting cell; DST; donor specific transfusion; IL; interleukin; IL2Fc; IL-2 fusion protein; IL15Fc; IL-15 fusion protein; ITN; Immu
Pollen metabolome analysis reveals adenosine as a major regulator of dendritic cell-primed TH cell responses
Keywords: Dendritic cells; immunomodulation; adenosine; pollen; allergy; ADA; Adenosine deaminase; APE; Aqueous pollen extract; cAMP; 3â²-5â²-Cyclic adenosine monophosphate; CFSE; Carboxyfluorescein succinimidyl ester; DC; Dendritic cell; FITC; Fluorescein isothi
Linfocitos T reguladores: Subpoblaciones, mecanismo de acción e importancia en el control de la autoinmunidad
Keywords: fenotipo; singénicos; FoxP3; TGF-β; anergia; autóloga; escurfina; Treg; APC; células presentadoras de antÃgeno; receptor de células T (TCR); Complejo Mayor de Histocompatibilidad (CMH); phenotype; syngeneic; FoxP3; TGF-β; anergy; autologous; escurf
Asthma translational medicine: Report card
Keywords: ACQ; asthma control questionnaire; AHR; airway hyper-responsiveness; AP-1; activator protein 1; APC; antigen-presenting cell; AQLQ; asthma quality-of-life questionnaire; BALF; bronchoalveolar lavage fluid; CTLA-4; cytotoxic T lymphocyte-associated antigen
Tolerance Rather Than Immunity Protects From Helicobacter pylori-Induced Gastric Preneoplasia
Keywords: Helicobacter pylori; Gastric Cancer; Neonatal Tolerance; Regulatory T Cells; CagA; cytotoxin-associated gene A; dnTβRII; dominant-negative form of the TGF-β receptor II; DT; diphtheria toxin; ELISA; enzyme-linked immunosorbent assay; IFN-γ; interferon
Attenuation of CNS inflammatory responses by nicotine involves α7 and non-α7 nicotinic receptors
Keywords: nAChR; nicotinic acetylcholine receptor; MS; multiple sclerosis; EAE; experimental autoimmune encephalomyelitis; MOG; myelin oligodendrocyte glycoprotein; Treg; regulatory T cell; MRI; magnetic resonance imaging;
Interleukins, from 1 to 37, and interferon-γ: Receptors, functions, and roles in diseases
Keywords: Cytokines; interleukins; T cells; B cells; dendritic cells; adaptive immune response; humoral immune response; allergy and asthma; APC; Antigen-presenting cell; CSF; Colony-stimulating factor; DC; Dendritic cell; FoxP3; Forkhead box protein 3; γc; γ-Cha
Phenotypical and functional alterations of CD8 regulatory T cells in primary biliary cirrhosis
Keywords: Autoimmune cholangitis CD8 T regulatory cells; IL7-R; CD39; PBC; primary biliary cirrhosis; AMA; anti-mitochondrial antibodies; ANA; anti-nuclear antibodies; Treg; regulatory T lymphocytes; UDCA; ursodeoxycholic acid; PBMC; peripheral blood mononuclear ce
Sensitive detection of Foxp3 expression in bovine lymphocytes by flow cytometry
Keywords: Cattle; Treg; Foxp3; Flow cytometry
A standardized aqueous extract of Anoectochilus formosanus modulated airway hyperresponsiveness in an OVA-inhaled murine model
Keywords: Anoectochilus formosanus; Airway hyperresponsiveness; Treg; Th1/Th2
Fine tuning T lymphocytes: A role for the lipid phosphatase SHIP-1
Keywords: T Lymphocyte; Lipid phosphatase; PI3K; Chemotaxis; miRNA; TReg;
Downregulation of IL-17 and IFN-γ in the optic nerve by β-elemene in experimental autoimmune encephalomyelitis
Keywords: β-elemene; Optic nerve; Treg; Th1; Th17
Repeated bouts of aerobic exercise enhance regulatory T cell responses in a murine asthma model
Keywords: Treg; Asthma; Aerobic exercise; Regulatory T cells
Salmon cartilage proteoglycan suppresses mouse experimental colitis through induction of Foxp3+ regulatory T cells
Keywords: Proteoglycan; Inflammatory bowel disease; Th1; Th17; RORγt; Treg; Foxp3;
Research ArticleAbundant numbers of regulatory T cells localize to the liver of chronic hepatitis C infected patients and limit the extent of fibrosis
Keywords: Hepatitis C virus; Regulatory T cell; Viral infection; FoxP3; Liver; Fibrosis; HCV; hepatitis C virus; Treg; regulatory T cell;
IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients
Keywords: Autoimmune arthritis; Th17; IL-10; Treg; Foxp3
Research ArticleThe novel immunoregulatory molecule FGL2: A potential biomarker for severity of chronic hepatitis C virus infection
Keywords: DC; dendritic cells; FGL2; fibrinogen-like protein 2; HBV; hepatitis B virus; HCV; hepatitis C virus; MHV-3; murine hepatitis virus strain 3; SVR; sustained virological response; Treg; CD4+CD25+ regulatory T cells; FGL2; HCV; Treg cells;
Asthma and lower airway diseaseMontelukast treatment may alter the early efficacy of immunotherapy in children with asthma
Keywords: Immunotherapy; asthma; montelukast; Foxp3; Forkhead box protein 3; HPRT1; Hypoxanthine phosphoribosyltransferase; ICS; Inhaled glucocorticosteroid; ITT; Intent-to-treat; PP; Per-protocol; SIT; Allergen-specific immunotherapy; Treg; Regulatory T;
Defect of regulatory T cells in patients with Omenn syndrome
Keywords: Immunodeficiency; V(D)J recombination; Omenn syndrome; regulatory T cells; FOXP3; anergy and tolerance; thymus and the development of T lymphocytes; AIRE; Autoimmune regulator; FOXP3; Forkhead box protein P3; HD; Healthy donor; OS; Omenn syndrome; RAG; Re
Mechanism of Synergistic Antitumor Effect of Sorafenib and Interferon-α on Treatment of Renal Cell Carcinoma
Keywords: kidney; carcinoma; renal cell; sorafenib; interferon-alpha; antineoplastic combined chemotherapy protocols; CI; combination index; CTL; cytotoxic T lymphocyte; DC; dendritic cell; Fa; fraction affected; HLBI; human lymphoblastoid IFN-α; IC; inhibitory co
The intestinal antiinflammatory agent glycomacropeptide has immunomodulatory actions on rat splenocytes
Keywords: Glycomacropeptide; STAT4; Inflammatory bowel disease; Th1; Treg; Foxp3
Genetic control of the inflammatory T-cell response in regulatory T-cell deficient scurfy mice
Keywords: Multi-organ inflammation; Scurfy mice; Genetic regulation; Ag; antigen; foxp3sf; foxp3 gene mutation in Sf mice; GPI; Glucose-6-phosphate Isomerase; MOI; Multi-organ Inflammation; OVA323-339; peptide #323 to 339 of ovalbumin; Sf; Scurfy mice; SMG; subma
Thymic changes after chorioamnionitis induced by intraamniotic lipopolysaccharide in fetal sheep
Keywords: Fetal inflammatory response syndrome; FoxP3; immune response; preterm; T lymphocyte; Treg;
The Th17/Treg functional imbalance during atherogenesis in ApoE−/− mice
Keywords: Atherosclerosis; Th17; Treg; Inflammation
Enrichment of CCR6+Foxp3+ regulatory T cells in the tumor mass correlates with impaired CD8+ T cell function and poor prognosis of breast cancer
Keywords: Treg; CCR6; TIL; Breast cancer; Prognosis