دانلود مقالات ISI درباره Trpm8 + ترجمه فارسی

Serendipity in drug-discovery: A new series of 2-(benzyloxy)benzamides as TRPM8 antagonists

Keywords: TRPM8; Library design; Multi-dimensional scaling; Lead hopping; 1,3-Diamino cyclohexane

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Activation of TRPM8 cold receptor triggers allodynia-like behavior in spinally injured rats

Keywords: Allodynia; Cold stimulation; Neuropathic pain; TRP receptors; TRPM8; Spinal cord injury

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

TRPM8 ion channel ligands for new therapeutic applications and as probes to study menthol pharmacology

Keywords: TRPM8; Agonist; Antagonist; Menthol; Nicotine; Addiction

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Lack of correlation between the amplitudes of TRP channel-mediated responses to weak and strong stimuli in intracellular Ca2+ imaging experiments

Keywords: TRPV1; TRPV4; TRPM3; TRPM8; TRPA1; PMCA; Calcium imaging; Fluorescence-activated cell sorting

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2013 سفارش ترجمه

Discovery of vinylcycloalkyl-substituted benzimidazole TRPM8 antagonists effective in the treatment of cold allodynia

Keywords: TRPM8; Transient receptor potential melastatin; Ion channel; Pain; Cold allodynia; Cold hypersensitivity; Benzimidazole;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The design and synthesis of novel, phosphonate-containing transient receptor potential melastatin 8 (TRPM8) antagonists

Keywords: Transient receptor potential; Melostatin 8; Cold menthol receptor (CMR1); TRPM8; Cold allodynia

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

Modulation of thermo-transient receptor potential (thermo-TRP) channels by thymol-based compounds

Keywords: Thermo-TRP channels; TRPA1; TRPM8; TRPV3; Tymol derivatives; p-Cymene-3-carboxylic acid derivatives; 3-Amino-p-cymene derivatives

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

The influence of TRPM8 ion channel activation on immune response at different temperature conditions

Keywords: TRPM8; Immune response; Cooling; Heating;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Regulation of TRPM8 channel activity

Keywords: PtdIns(4,5)P2; PIP2; TRP channel; TRPM8; Temperature sensation;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Topical hindpaw application of L-menthol decreases responsiveness to heat with biphasic effects on cold sensitivity of rat lumbar dorsal horn neurons

Keywords: ANOVA; analysis of variance; DRG; dorsal root ganglion; GABA; gamma amino butyric acid; GFP; green fluorescent protein; MI; mechanically insensitive; NS; nociceptive specific; PSTH; peristimulus-time histogram; SEM; standard error of the mean; TRPA1; tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Mechanisms in cancer-chemotherapeutic drugs-induced peripheral neuropathy

Keywords: CIPN; cancer chemotherapy-induced peripheral neuropathy; CGRP; calcitonin gene related peptide; cGMP; cyclic guanosine monophosphate; CRPS-I; complex regional pain syndrome; Cyt C; cytochrome C; DRG; dorsal root ganglia; ERK; extracellular signal regulate

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Comparing ion conductance recordings of synthetic lipid bilayers with cell membranes containing TRP channels

Keywords: TRP channel; TRPA1; TRPM2; TRPM8; Lipid pore; Phase transition;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of oxaliplatin-induced chronic painful peripheral neuropathy in the rat and comparison with the neuropathy induced by paclitaxel

Keywords: chemotherapy neuropathy; carnitine; olesoxime; mitotoxicity; sensory neuropathy; ALCAR; acetyl-l-carnitine; ATF-3; activating transcription factor 3; BUN; blood urea nitrogen; CIPN; chemotherapy-induced peripheral neuropathy; CMAP; compound muscle action

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Characterization of bilateral trigeminal constriction injury using an operant facial pain assay

Keywords: ANOVA; analyses of variance; CCI; chronic constriction injury; PBS; phosphate-buffered saline; TRPM8; transient receptor potential channel melastatin 8; TRPV1; transient receptor potential channel vanilloid 1; trigeminal neuropathic pain; operant; TRPM8;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2012 سفارش ترجمه

Icilin induces G1 arrest through activating JNK and p38 kinase in a TRPM8-independent manner

Keywords: AIPC, androgen-independent prostate cancerIcilin; Cell cycle; Prostate cancer; JNK; p38; TRPM8

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Function and expression pattern of TRPM8 in bladder afferent neurons associated with bladder outlet obstruction in rats

Keywords: TRPM8; Urinary bladder; Rat; TRPV1; Bladder cooling reflex; Bladder outlet obstruction;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Examination of the role of TRPM8 in human mast cell activation and its relevance to the etiology of cold-induced urticaria

Keywords: TRPM8; Calcium; Mast cells; Cold-induced urticaria; FcɛRI; Degranulation

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Research ReportIcilin-evoked behavioral stimulation is attenuated by alpha2-adrenoceptor activation

Keywords: Neurotransmitters, Modulators, Transporters, and Receptors; Interactions between neurotransmitters; Behavioral pharmacology; Clonidine; Icilin; TRPM8; Wet-dog shake; Alpha2-adrenoceptor; Agmatine; ST91; Yohimbine;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

Cold temperature induces mucin hypersecretion from normal human bronchial epithelial cells in vitro through a transient receptor potential melastatin 8 (TRPM8)-mediated mechanism

Keywords: Transient receptor potential melastatin 8; mucus hypersecretion; MUC5AC; cold air; myristoylated alanine-rich C kinase substrate; Ca2+; phosphatidylinositol 4,5-bisphosphate; BCTC; N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl) piperazine-1-carboxamide;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2011 سفارش ترجمه

(−)-Menthylamine derivatives as potent and selective antagonists of transient receptor potential melastatin type-8 (TRPM8) channels

Keywords: Transient receptor potential channels; TRPA1; TRPV1; TRPM8; (−)-Menthylamine derivatives

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

5-Benzyloxytryptamine as an antagonist of TRPM8

Keywords: Transient receptor potential; TRP; TRPM8; Antagonist; Menthol; Icilin; 5-Benzyloxytryptamine

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

AFM imaging reveals the tetrameric structure of the TRPM8 channel

Keywords: Transient receptor potential channels; TRPM8; Channel assembly; Subunit stoichiometry; Atomic force microscopy

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2010 سفارش ترجمه

Differential effects of substance P or hemokinin-1 on transient receptor potential channels, TRPV1, TRPA1 and TRPM8, in the rat

Keywords: Substance P; Hemokinin-1; TRPV1; TRPA1; TRPM8; Scratching behavior; Intrathecal administration

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2010 سفارش ترجمه

Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma

Keywords: Transient receptor potential (TRP); TRPM8; Ion channel; Proliferation; Pancreatic cancer

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

TRPM8 mediates cold and menthol allergies associated with mast cell activation

Keywords: TRPM8; Menthol; Cold allergy; Histamine; BCTC

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Agonist of TRPM8 channel, menthol, facilitates the initiation of thermoregulatory responses to external cooling

Keywords: Cold; TRPM8; Thermoregulatory response; Temperature threshold

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2010 سفارش ترجمه

Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons

Keywords: Nociceptive; Non-nociceptive; Peptidergic; TRP channels; Expression; mRNA; Neuron; In situ hybridization; Dorsal root ganglion; Nodose ganglion; Sensory nervous system; TRPM8; Immunohistochemistry; PCR

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2010 سفارش ترجمه

Differential ATF3 expression in dorsal root ganglion neurons reveals the profile of primary afferents engaged by diverse noxious chemical stimuli

Keywords: DRG; Nerve injury; Capsaicin; Formalin; Mustard oil; Menthol; TRPV1; TRPA1; TRPM8;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2010 سفارش ترجمه

The development of peripheral cold neural circuits based on TRPM8 expression

Keywords: temperature; TRPM8; cold; menthol; DRG; developmentCGRP, calcitonin gene-related peptide; DRG, dorsal root ganglia; eGFP, green fluorescent protein; IR, immunoreactive; NGF, nerve growth factor; Trpm8GFP, trpm8 transcriptional promoter

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2010 سفارش ترجمه

Role of voluntary motor activity on menthol-induced hyperthermia in mice

Keywords: Thermoregulation; TRPM8; Transient receptor potential ion channels; Skin temperature;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Menthol regulates TRPM8-independent processes in PC-3 prostate cancer cells

Keywords: TRPM8, transient receptor potential melastatin 8; I–V curve, current to voltage relation curve; JNK, c-jun N-terminal kinaseMenthol; TRPM8; Ca2+; Prostate cancer; Cell death

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2009 سفارش ترجمه

Expression of the TRPM8-immunoreactivity in dorsal root ganglion neurons innervating the rat urinary bladder

Keywords: TRPM8; Urinary bladder; Dorsal root ganglion; NF200; TRPV1; CGRP; IB4; Rat

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2009 سفارش ترجمه

Comparative modeling of the quaternary structure for the human TRPM8 channel and analysis of its binding features

Keywords: TRPM8; Menthol; Icilin; Cold-sensitive ion channel; Homology modelling by fragment; Molecular docking;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2009 سفارش ترجمه

Transient receptor potential vanilloid 1, vanilloid 2 and melastatin 8 immunoreactive nerve fibers in human skin from individuals with and without Norrbottnian congenital insensitivity to pain

Keywords: calcitonin-gene related peptide; immunohistochemistry; pain; sensory neuron; skin; transient receptor potential channels; CGRP; calcitonin gene-related peptide; CT; cycle threshold; F; female; HET; heterozygous; HO; homozygous; M; male; NF200; neurofilame

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2009 سفارش ترجمه

Roles of transient receptor potential channels in pain

Keywords: TRPA1; TRPV1; TRPM8; Cold; Mechanotransduction; Nociceptor; Sensory neuron; Cutaneous; Inflammation; Prostaglandin; NGF; Artemin; Bradykinin; Kinase; Scaffold protein

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2009 سفارش ترجمه

Cross-desensitization of responses of rat trigeminal subnucleus caudalis neurons to cinnamaldehyde and menthol

Keywords: Menthol; Cinnamaldehyde; TRPM8; TRPA1; Cold; Trigeminal

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2008 سفارش ترجمه

HGF/SF and menthol increase human glioblastoma cell calcium and migration

Keywords: Transient receptor potential ion channel; TRPM8; Hepatocyte growth factor/scatter factor; HGF/SF; DBTRG; Migration; Glioblastoma; Calcium

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2008 سفارش ترجمه

Icilin induces a hyperthermia in rats that is dependent on nitric oxide production and NMDA receptor activation

Keywords: Icilin; TRPM8; Nitric oxide; l-NAME; NMDA; LY 235959; Hyperthermia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2008 سفارش ترجمه

Role of TRPM8 and TRPA1 for cold allodynia in patients with cold injury

Keywords: Cold hypersensitivity; Cold allodynia; Cold injury; Menthol; Cinnamaldehyde; Temperature threshold; Axon-reflex-flare; Psychophysics; TRPM8; TRPA1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Comparison of icilin- and cold-evoked responses of spinal neurones, and their modulation of mechanical activity, in a model of neuropathic pain

Keywords: Spinal cord; Primary afferent fibre; Cold allodynia; TRPM8; TRPA1;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2008 سفارش ترجمه

Increased TRPA1, TRPM8, and TRPV2 expression in dorsal root ganglia by nerve injury

Keywords: Transient receptor potential; Temperature; TRPV1; TRPV2; TRPV3; TRPV4; TRPA1; TRPM8; Neuropathic pain; Cold hypersensitivity

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2007 سفارش ترجمه

Regulation of transient receptor potential channels of melastatin type 8 (TRPM8): Effect of cAMP, cannabinoid CB1 receptors and endovanilloids

Keywords: Cannabinoid; TRPM8; TRPV1; Calcium;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Plasticity in intact Aδ- and C-fibers contributes to cold hypersensitivity in neuropathic rats

Keywords: peripheral neuropathy; sensitization; TRPA1; TRPM8; neuropathic pain; cold allodynia; ADM; Aδ-mechanical unit; ADMC; Aδ-mechanocold unit; ADMH; Aδ-mechanoheat unit; ADMHC; Aδ-mechanoheat-cold unit; CM; C-mechanoreceptor unit; CMC; C-mechanocold unit;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

A pharmacological study of slowly adapting mechanoreceptors responsive to cold thermal stimulation

Keywords: TRP; TRPM8; icilin; TEA; K channels; coolCOV, coefficient of variation; SIF, synthetic interstitial fluid; TEA, tetraethylammonium chloride; TRP, transient receptor potential

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2007 سفارش ترجمه

Ca2+-dependent PKC activation mediates menthol-induced desensitization of transient receptor potential M8

Keywords: Cold/menthol receptor; TRPM8; PKC; PMA; Non-selective cation channel

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2006 سفارش ترجمه

Improved superfusion technique for rapid cooling or heating of cultured cells under patch-clamp conditions

Keywords: Feedback controlled Peltier device; Temperature control; TRPV1; TRPM8; Capsaicin; Menthol

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2006 سفارش ترجمه

Molecular identification and functional characterization of a temperature-sensitive transient receptor potential channel (TRPM8) from canine

Keywords: TRPM8; Menthol; Icilin; Cold allodynia; Thermosensation; Canine

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2006 سفارش ترجمه

Antisense knock down of TRPA1, but not TRPM8, alleviates cold hyperalgesia after spinal nerve ligation in rats

Keywords: Neuropathic pain; TRPA1; TRPM8; Dorsal root ganglion; Spared neurons

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

Cold sensitivity in axotomized fibers of experimental neuromas in mice

Keywords: Cold hyperalgesia; Neuropathic pain; TRPM8; Menthol

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2006 سفارش ترجمه

TRPM8 protein localization in trigeminal ganglion and taste papillae

Keywords: Trigeminal ganglion; TRPM8; Thermosensitive neuron; Immunohistochemistry; Neurotransmitters, modulators, transporters, and receptors; Regional localization of receptors and transmitters; Cold and menthol receptor-1; Trigeminal ganglion; Fungiform papilla;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2005 سفارش ترجمه