Keywords: HMG-CoA R; 3-hydroxy-3-methylglutaryl-coenzyme A reductase; 3α-diol; 5alpha-androstane-3alpha,17beta-diol; 3β-diol; 5alpha-androstane-3beta,17beta-diol; 7α-OH; 7α-hydroxycholesterol; 7β-OH; 7β-hydroxycholesterol; 7-keto; 7-ketocholesterol; 24(S)-OH;
مقالات ISI (ترجمه نشده)
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Keywords: AD; Alzheimer's disease; ARA; arachidonic acid; CD; cluster of differentiation; iPLA2; calcium independent phospholipase A2; cPLA2; cytosolic phospholipase A2; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; HDHA; hydroxy DHA; HETE; hydroxyeicosa
Keywords: Multiple sclerosis; Disease modifying therapy; Microglia; Positron emission tomography; TSPO; [11C]DPA713;
Keywords: AgRP; Agouti-related protein; ARC; Arcuate nucleus; BMI; Body mass index; Clâ; Chloride ion; CNS; Central nervous system; GABA; γ-aminobutyric acid; GABAA-receptor; γ-aminobutyric acid receptor type A; GAMS; GABAA-receptor modulating steroids; GAMSA;
Keywords: ABA; abscisic acid; ABI; ABA-insensitive; AIM/LIR; ATG8-interacting motif/LC3-interacting region; AREB/ABFs; ABRE-binding protein/ABRE-binding factor; ARM; armadillo repeat; Atg8; autophagy-related 8; BAG6; BCL-2 associated athanogene 6; BiPs; lumenal bin
Keywords: Diffusion; PET; TSPO; Primary lateral sclerosis; Amyotrophic lateral sclerosis; [11C]-PBR28;
Keywords: Depressive disorder; Inflammation; ECT; Immune; Cortisol; ACTH; Adrenocorticotropic hormone; AVP; arginine vasopressin; BDI; Beck Depression Inventory; BL-BT; Bilateral-Bitemporal; BP; Bipolar Disorders; CMI test; serotonin uptake inhibitor clomipramine;
Short communicationDevelopment and characterization of mitochondrial membrane affinity chromatography columns derived from skeletal muscle and platelets for the study of mitochondrial transmembrane proteins
Keywords: OMM; outer mitochondrial membrane; IMM; inner mitochondrial membrane; TSPO; translocator protein; MMAC; mitochondrial membrane affinity chromatography; DIPY; dipyridamole; PIX; protoporphyrin IX; PK; PK-11195; Rot; rotenone; IAM; immobilized artificial me
Keywords: Photodynamic therapy; CB2 receptor; TSPO; Synergistic; Combination therapy;
Keywords: APC; allophycocyanin; CFA; complete Freund's adjuvant; CNS; central nervous system; dpi; day post-induction; DTH; delayed-type hypersensitivity; Dz; Diazepam; EAE; Experimental autoimmune encephalomyelitis; FITC; fluorescein isothiocyanate; GABA; γ-amino
Keywords: MCAO; middle cerebral artery occlusion; NMDA; N-methyl-d-aspartic acid; tPA; tissue plasminogen activator; WEST; Women Estrogen Stroke Trial; TSPO; translocator protein; TPEN; N,N,Nʹ,Nʹ-tetrakis (2-pyridylmethyl) ethylenediamine; CCA; common carotid art
Keywords: Depression; Hippocampus; Multiple sclerosis; Neuroimaging; Neuroinflammation; TSPO;
Keywords: CERT; ceramide transfer protein; CETP; cholesteryl ester transfer protein; ER; endoplasmic reticulum; FABP; fatty acid-binding protein; FFAT; diphenylalanine in an acidic tract; GAP; GTPase-activating protein; GEF; guanine nucleotide exchange factor; GLs;
Keywords: Aging; Testosterone; Hypogonadism; TSPO;
Keywords: ANT; adenine nucleotide translocase; CsA; cyclosporin A; CyP; cyclophilin; Drp1; dynamin-related protein 1; ÎÏm; mitochondrial membrane potential; ERK; extracellular signal regulated kinase; GSK; glycogen synthase kinase; IMM; inner mitochondrial membra
Keywords: Alzheimer's disease; Dementia; Neurodegenerative disease; neuroinflammation; Microglial activation; PET; TSPO; MRI;
Keywords: ADP; adenosine diphosphate; ANT; adenine nucleotide transporter; ATP; adenine triphosphate; C1QBP; complement component 1Q subcomponent-binding protein; Ca2Â +; calcium; CK; creatine kinase; CsA; cyclosporine A; CYCLE; CYCLosporinE A in reperfused acute m
Keywords: Akt; also known as protein kinase B; ANT; adenine nucleotide translocase; Bad; Bcl-2-associated death promoter; Bak; Bcl-2 homologous antagonist/killer; Bax; Bcl-2-like protein 4; Bcl2; B cell lymphoma 2; Bcl-xL; B-cell lymphoma-extra large; Bid; BH3 inte
Keywords: ALP; alkaline phosphatase; ALT; alanine transaminase; ANOVA; one-way analysis of variance; AST; aspartate transaminase; Cyp11a1; cholesterol side-chain cleavage enzyme; DHT; dihydrotestosterone; FSH; follicle stimulating hormone; 3β-HSD; 3β-hydroxystero
Keywords: FEP; first-episode psychosis; PCR; polymerase chain reaction; PANSS; Positive and Negative Syndrome Scale; GABRR2; gamma-aminobutyric acid (GABA) receptor, rho 2; GABA; gamma-aminobutyric acid; mRNA; messenger ribonucleic acid; RNA; ribonucleic acid; qPCR
Keywords: ANT; adenine nucleotide translocase; [Ca2+]c; cytosolic calcium concentration; [Ca2+]m; mitochondrial calcium concentration; CsA; cyclosporine A; HK; hexokinase II; H2O2; hydrogen peroxide; IB; intracellular milieu; MCU; mitochondrial Ca2+ uniporter; NCLX
Keywords: HPA; Hypothalamus-pituitary- adrenal axis; BDNF; Brain-derived neurotrophic factor; TSST; Trier Social Stress test; SBBS; Steroidogenic stimulant; CRF; Corticotropin releasing factor; mPFC; median prefrontal cortex; PBR; Peripheral benzodiazepine receptor
Keywords: α-sma; alpha smooth muscle actin; BSA; bovine serum albumin; cc-3; cleaved caspase-3; Cho; choroid; GFAP; glial fibrillary acidic protein; IB4; isolectin B4; Iba1; ionized calcium binding adapter molecule 1; INL; inner nuclear layer; NG2; neuron-glial an
Keywords: AMT; α-methyl-l-tryptophan; BBB; blood-brain barrier; CB1; cannabinoid receptor type 1; CB2; cannabinoid receptor type 2; CNS; central nervous system; FLAIR; fluid-attenuated inversion recovery; Gd-DTPA; gadolinium-diethylenetriaminepentacetate; GFAP;
Keywords: CYP11A1; cytochrome P450, family 11, subfamily A, polypeptide 1; PKA; cyclic-AMP-dependent protein kinase; ACTH; adrenocorticotropin hormone; LH; luteinizing hormone; IMM; inner mitochondrial membrane; P5; pregnenolone; ER; the endoplasmic reticulum; OMM;
Keywords: 1,25(OH)2D; 1,25 dihydroxy vitamin D (calcitriol); 3βHSD; 3β-hydroxysteroid dehydrogenase; ACAT; acyl transferase; ACTH; adrenocorticotropic hormone; ANT; adenine nucleotide transporter; ER; endoplasmic reticulum; CRAC; cholesterol recognition amino aci
Keywords: 22R-OHC; 22R-hydroxycholesterol; ACTH; adrenocorticotropic hormone; ALC; adult Leydig cells; ATIIR; angiotensin receptor; DEHP; di-(2-ethylhexyl) phthalate; DHEA; dehydroepiandrosterone; DHEAS; sulfated dehydroepiandrosterone; EHXA; 2-ethylhexanoic acid;
TSPO and amyloid deposits in sub-regions of the hippocampus in the 3xTgAD mouse model of Alzheimer's disease
Keywords: Neuroinflammation; Alzheimer's disease; TSPO; CLINDE; DRM106; 3xTgAD; TSPO; 18kDa translocator protein; SPECT; single-photon emission computed tomography;
Cytoprotective effects of paeoniflorin are associated with translocator protein 18â¯kDa
Keywords: Cytoprotection; Neurosteroids; PF; TSPO;
[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18â¯kDa)
Keywords: [18F]DAA1106; Spirocyclic iodonium ylide; [18F]Fluorination; TSPO; Ischemia;
Translocator protein (TSPO) and stress cascades in mouse models of psychosis with inflammatory disturbances
Keywords: CBL; cerebellum; CON; control; CSE; cuprizone short-term exposure; HP; hippocampus; HPA; hypothalamic-pituitary-adrenal; MIA; maternal immune activation; PET; positron emission tomography; PFC; prefrontal cortex; poly(I:C); polyinosinic:polycytidylic acid
Effects of chronic antipsychotic drug exposure on the expression of Translocator Protein and inflammatory markers in rat adipose tissue
Keywords: Olanzapine; Inflammation; TSPO; Adipose; Macrophage; Antipsychotic;
Non-invasive estimation of [11C]PBR28 binding potential
Keywords: [11C]PBR28; Neuroinflammation; Alzheimer's disease; Kinetic modeling; PET; TSPO;
Evaluation of the novel TSPO radiotracer 2-(7-butyl-2-(4-(2-([18F]fluoroethoxy)phenyl)-5-methylpyrazolo[1,5-a]pyrimidin-3-yl)-N,N-diethylacetamide in a preclinical model of neuroinflammation
Keywords: Neuroinflammation; Positron Emission Tomography (PET); TSPO; [18F]DPA-714; [18F]VUIIS1018A;
Phytohormone participation during Citrus sinensis non-host response to Xanthomonas campestris pv. vesicatoria
Keywords: Biotic stress; Incompatible interaction; Plant - pathogen interaction; Sweet orange; Transcriptomic analysis; Xanthomonas citri subsp. citri; ABA; Abscisic Acid; ABA1/ZEP; Zeaxanthin epoxidase; ABF3/DPBF5; Abscisic acid responsive elements-binding factor
Overexpressed ACBD3 has prognostic value in human breast cancer and promotes the self-renewal potential of breast cancer cells by activating the Wnt/beta-catenin signaling pathway
Keywords: ACBD3; Acyl-CoA binding domain containing 3; ER; estrogen receptor; PR; progesterone receptor; Her2; human epidermal growth factor receptor-2; CSC; cancer stem cell; BCSC; breast cancer stem cell; EGFR; epidermal growth factor receptor; ACBP; acyl-CoA-bin
Chronic benzodiazepine suppresses translocator protein and elevates amyloid β in mice
Keywords: AD; Alzheimer's disease; Aβ; amyloid β; cBZD; chronic benzodiazepine; MMS; mitochondrial membrane swelling; TSPO; translocator protein; PS1; presenilin-1; ROS; reactive O2 species;
Long-term inhibition of PDE5 ameliorates aging-induced changes in rat testis
Keywords: Actb/ACTB; gene/protein for β-actin; AKT; protein for protein kinase B (AKT/PRKGB); BSA; bovine serum albumin; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; Cyp11a1; gene for cytochrome P450 side chain cleavage enzyme; Cyp17
Fatty acid activates NLRP3 inflammasomes in mouse Kupffer cells through mitochondrial DNA release
Keywords: NAFLD; Non-alcoholic fatty liver disease; NLRP3; NACHT, LRR, and PYD domains-containing protein 3; NAFL; Non-alcoholic fatty liver; NASH; non-alcoholic steatohepatitis; FFA; free fatty acid; PA; palmitic acid; KCs; Kupffer cells; MCD; methionine choline d
Increased brain docosahexaenoic acid has no effect on the resolution of neuroinflammation following intracerebroventricular lipopolysaccharide injection
Keywords: Neuroinflammation; Lipopolysaccharide; Microglia; Resolution of neuroinflammation; Omega-3 polyunsaturated fatty acids; CCL; chemokine (c-c motif) ligand; CD; cluster of differentiation; COX; cyclooxygenase; DHA; docosahexaenoic acid; EPA; eicosapentaenoi
Molecular Imaging of Myocardial Inflammation With Positron Emission Tomography Post-Ischemia
Keywords: [18F]fluorodeoxyglucose; inflammation; leukocytes; macrophages; molecular imaging; myocardial infarction; [18F]FDG; 18F-labeled fluorodeoxyglucose; CCL12; chemokine (C-C motif) ligand 12; CX3CL1; chemokine (C-X3-C motif) ligand 1 (fractalkine); CXCR4; che
TSPO ligand PK11195 improves Alzheimer-related outcomes in aged female 3xTg-AD mice
Keywords: TSPO; translocator protein 18â¯kD; AD; Alzheimer's disease; Aging; Alzheimer's; β-Amyloid; Neuroinflammation; TSPO;
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [18F]GE180 PET quantification
Keywords: TSPO; [18F]GE180; Small animal PET; Brain uptake normalization; Myocardium;
Functional TSPO polymorphism predicts variance in the diurnal cortisol rhythm in bipolar disorder
Keywords: Bipolar disorder; Biomarker; Stress; Cortisol; Immune; Genetics; TSPO; rs6971; Alcohol use disorder; Variance factor; Diurnal rhythm; HPA axis; Precision medicine;
Dynamic TSPO-PET for assessing early effects of cerebral hypoxia and resuscitation in new born pigs
Keywords: [18F]GE180; Microglia activation; Perinatal hypoxia ischemia; PET; Piglet; TSPO;
Neuroprotective effect of zolpidem against glutamate-induced toxicity is mediated via the PI3K/Akt pathway and inhibited by PK11195
Keywords: ANC; adenine nucleotide carrier; H2O2; hydrogen peroxide; LDH; lactate dehydrogenase; mPTP; mitochondrial permeability transition pore; PI3K; phosphatidylinositol-3-kinase; PK11195; 1-(-2-chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide
Microglial positron emission tomography (PET) imaging in epilepsy: Applications, opportunities and pitfalls
Keywords: Epilepsy; Microglia; Positron emission tomography; PET; Translocator protein; TSPO;
Progesterone treatment modulates mRNA OF neurosteroidogenic enzymes in a murine model of multiple sclerosis
Keywords: CC1; anti-adenomatours polyposis coli clone CC1; CD11b; cluster of differentiation molecule 11B; CFA; complete Freund adjuvant; DHP; dihydroprogesterone; EAE; experimental autoimmune encephalomyelitis; Fis1; mitochondrial fission 1; GABA; gamma-aminobutyr
A TSPO ligand prevents mitochondrial sterol accumulation and dysfunction during myocardial ischemia-reperfusion in hypercholesterolemic rats
Keywords: TSPO; translocator protein; ZDF; Zucker diabetic fatty; mPTP; mitochondrial permeability transition pore; Cardiac mitochondria; Sterol; Hypercholesterolemia; Ischemia-reperfusion injury; Translocator protein;
Non-invasive PET imaging of brain inflammation at disease onset predicts spontaneous recurrent seizures and reflects comorbidities
Keywords: SRS; spontaneous recurrent seizures; TSPO; translocator protein; PET; positron emission tomography; SE; status epilepticus; KA; kainic acid; KASE; kainic acid-induced status epilepticus; PED; periodic epileptiform discharge; vEEG; video-electroencephalogr