Keywords: TTR; transthyretin; wt-TTR; wild type-TTR; T4; thyroxine; HBP; halogen binding pocket; PDB; Protein Data Bank; Transthyretin; Amyloidosis; Protein misfolding; Fibrillogenesis inhibitor; Transthyretin stabilizer;
مقالات ISI (ترجمه نشده)
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Keywords: ECs; environmental chemicals; EDCs; endocrine-disrupting compounds; NIS; sodium-iodide symporter; fT3; free triiodothyronine; fT4; free thyroxine; TH; thyroid hormone; TSH; thyroid stimulating hormone; TR; thyroid hormone receptor; TTR; transthyretin; HPT
Keywords: AD; Alzheimer's disease; Aβ; amyloid-beta peptide; BSA; bovine serum albumin; CSF; cerebrospinal fluid; CM-H2DCFDA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DMSO; dimethylsulfoxide; DTT; dithiothreitol; D-PBS; Dulbecco's phosphate-buffered saline;
Keywords: dry eye; outcome measures; statistical analysis; tear physiology; ANCOVA; Analysis of covariance; ANOVA; Analysis of variance; EVAP; Evaporation rate; HPMC; Hydroxypropyl methylcellulose; KMO; Kaiser-Meyer-Olkin (measure of sampling adequacy); OSM; Osmola
Benzotriazoles, benzothiazoles and trace elements in an urban road setting in Trondheim, Norway: Re-visiting the chemical markers of traffic pollution
Keywords: BTHs; benzothiazoles; 2âSâBTH; 2âmercaptobenzothiazole; BTH; benzothiazole; 2âOHâBTH; 2âhydroxyâbenzothiazole; 2âMâBTH; 2âmorpholinâ4âylâbenzothiazole; 2âMeâSâBTH; 2âmethylthioâbenzothiazole; 2âABTH; 2âaminobenzothi
Quantitative analysis of in-vivo responses of reproductive and thyroid endpoints in male goldfish exposed to monocrotophos pesticide
Keywords: THs; thyroid hormones; T3; 3,3â²,5-triiodo-L-thyronine; T4; 3,3â²,5,5â²-L-thyroxine; HPT; hypothalamic-pituitary-thyroid; E2; 17β-estradiol; T; testosterone; HPG; hypothalamic- pituitary-gonadal; MCP; monocrotophos; CRH; corticotropin-releasing hormon
Oculoleptomeningeal Amyloidosis Secondary to the Rare Transthyretin c.381T>G (p.Ile127Met) Mutation
Keywords: Familial amyloidosis; Oculoleptomeningeal amyloidosis; Transthyretin; OLMA; Oculoleptomeningeal amyloidosis; TTR; Transthyretin;
T1 mapping on gadoxetic acid-enhanced MR imaging predicts recurrence of hepatocellular carcinoma after hepatectomy
Keywords: ADC; apparent diffusion coefficient; AFP; alpha-fetoprotein; BCLC stage; Barcelona Clinic Liver Cancer stage; CT; computed tomography; DW; diffusion-weighted; EM; extrahepatic recurrence; HBPI; hepatobiliary phase imaging; HCC; hepatocellular carcinoma; I
Anti-c-Mpl antibodies in immune thrombocytopenia suppress thrombopoiesis and decrease response to rhTPO
Keywords: (anti-c-Mpl) antibodies; anti-TPO receptor; anti-c-Mpl+; anti-c-Mpl-antibody-positive; anti-c-Mplâ; anti-c-Mpl-antibody-negative; ITP; immune thrombocytopenia; IVIG; intravenous immunoglobulin; TPO; thrombopoietin; TPO-RAs; TPO receptor agonists; rhTPO;
Comparison of in vitro and in vivo bioassays to measure thyroid hormone disrupting activity in water extracts
Keywords: In vitro; In vivo; Surface water; Thyroid activity; Wastewater; AmiEQ; amiodarone equivalent concentrations; DOC; dissolved organic carbon; EC; effect concentration; ETU; ethylene thiourea; IC; inhibition concentration; MMI; methimazole; MMIEQ; methimaz
Childhood polybrominated diphenyl ether (PBDE) exposure and executive function in children in the HOME Study
Keywords: BRIEF; Behavior Rating Inventory of Executive Function; CDC; Centers for Disease Control and Prevention; CI; confidence interval; CHAMACOS Study; Center for the Health Assessment of Mothers and Children of Salinas; FSIQ; full scale intelligence quotient;
Evaluation of low-intensity anti-coagulation with a fully magnetically levitated centrifugal-flow circulatory pump-the MAGENTUM 1 study
Keywords: HeartMate 3; INR management; left ventricular assist device; LVAD; reduced intensity anti-coagulation; Rosendaal method; TTR; time in therapeutic range;
Endothelial cells instruct liver specification of embryonic stem cell-derived endoderm through endothelial VEGFR2 signaling and endoderm epigenetic modifications
Keywords: Mouse embryonic stem cells; Endoderm hepatic specification; Endothelial cells; VEGFR2; Epigenetic modifications; ESC; human embryonic stem cell; EB; embryoid body; AL End; mouse ESC-derived endoderm cells cultured alone; CC End; mouse ESC-derived endoderm
A comparison of hatchery-rearing in exercise to wild animal physiology and reflex behavior in Aplysia californica
Keywords: MO2; resting oxygen consumption; TTR; time-to-right; TWR; tail withdrawal reflex; Time to right; Marine invertebrate; Isometric; Behavior; Aquaculture; Nervous system;
Identification of candidate biomarkers of the exposure to PCBs in contaminated cattle: A gene expression- and proteomic-based approach
Keywords: ACN; Acetonitrile; AhR; Aryl hydrocarbon receptor; APO; Apolipoprotein; CNRQ; Calibrated normalized relative quantity; DL; Dioxin-like; ESI-Q; Electrospray ionization quadrupole; GPX; Glutathione peroxidase; HP; Haptoglobin; IL-2; Interleukin 2; LIT; Line
A Propensity Score Matched Comparison of Clinical Outcomes in Atrial Fibrillation Patients Taking Vitamin K Antagonists: Comparing the “Real-World” vs Clinical Trials
Keywords: AF; atrial fibrillation; AMADEUS; Evaluating the Use of SR34006 Compared to Warfarin or Acenocoumarol in Patients With Atrial Fibrillation; CHA2DS2-VASc; Congestive heart failure or left ventricular dysfunction (1), Hypertension (1), Ageâ¥75 (2) or 65-74
Multiple approaches to assess the effects of F-53B, a Chinese PFOS alternative, on thyroid endocrine disruption at environmentally relevant concentrations
Keywords: F-53B; 6:2 chlorinated polyfluorinated ether sulfonate; PFOS; perfluorooctane sulfonate; HPT axis; hypothalamic-pituitary-thyroid axis; TRs; thyroid receptors; THs; thyroid hormones; CRH; corticotropin-releasing hormone; TSH; thyroid-stimulating hormone;
Combining 3D data and traditional soil erosion assessment techniques to study the effect of a vegetation cover gradient on hillslope runoff and soil erosion in a semi-arid catchment
Keywords: CDR; Ratio of 3D-estimated volume of deposition over erosion in channels; CumQ; Cumulative runoff volume (L); CumQ20; Cumulative runoff volume (L) recorded the first 20â¯min of rainfall; CumS; Cumulative soil loss (kg); CumS20; Cumulative soil loss (kg)
Prenatal and childhood exposure to per- and polyfluoroalkyl substances (PFASs) and child cognition
Keywords: ADHD; attention deficit hyperactivity disorder; CDC; Centers for Disease Control and Prevention; DAG; Directed Acyclic Graph; EtFOSAA; 2-(N-ethyl-perfluorooctane sulfonamido) acetate; FOSA; perfluorooctane sulfonamide; GFR; glomerular filtration rate; GM;
Molecular and thyroid hormone binding properties of lamprey transthyretins: The role of an N-terminal histidine-rich segment in hormone binding with high affinity
Keywords: Transthyretin; Thyroid hormone; Zinc; 5-hydroxyisourate hydrolase; Lamprey; BSA; bovine serum albumin; CBB; Coomassie Brilliant Blue; EDTA; ethylenediaminetetraacetic acid; HIC; hydrophobic interaction column chromatography; HIU; 5-hydroxyisourate; HIUHas
Evaluation of HE4 and TTR for diagnosis of ovarian cancer: Comparison with CA-125
Keywords: Sandwich ELISA; CA-125; HE4; TTR; Diagnosis; Ovarian cancer;
Bleeding predictors in patients following venous thromboembolism treated with vitamin K antagonists: Association with increased number of single nucleotide polymorphisms
Keywords: Venous thromboembolism; Vitamin K antagonists; Acenocoumarol; Warfarin; Genetic polymorphisms; AF; atrial fibrillation; APOE; apolipoprotein E; AUC; area under the curve; CI; confidence interval; CRNM bleeding; clinically relevant non-major bleeding; CYP2
Apolipoproteins C-II and C-III as nutritional markers unaffected by inflammation
Keywords: Albumin; Lipoprotein; Malnutrition; Nutrition support team; Rapid turnover protein; AP1; activator protein 1; Apo; apolipoprotein; CAPD; continuous ambulatory peritoneal dialysis; C/EBPs; CCAAT/enhancer-binding proteins; CRP; C-reactive protein; CV; coeff
Maternal betaine administration modulates hepatic type 1 iodothyronine deiodinase (Dio1) expression in chicken offspring through epigenetic modifications
Keywords: AHCYL1; adenosylhomocysteinase-like 1; BHMT; betaineâhomocysteineâSâmethyltransferase; DNMT1; DNA methyltransferase 1; Dio1; type 1 iodothyronine deiodinase; Dio2; type 2 iodothyronine deiodinase; Dio3; type 3 iodothyronine deiodinase; LAT1; L-type
A chemometric approach for characterization of serum transthyretin in familial amyloidotic polyneuropathy type I (FAP-I) by electrospray ionization-ion mobility mass spectrometry
Keywords: COW; correlation optimized warping; FAP-I; familial amyloidotic polyneuropathy type I; IM-MS; ion mobility mass spectrometry; IP; immunoprecipitation; LV; latent variable; MCR-ALS; multivariate curve resolution alternating least squares; Mr; relative mole
Physicochemical characterization of 6-O-acyl trehalose fatty acid monoesters in desiccated system
Keywords: ÎCp; heat capacity change; Cr; crystal; Q; cubic liquid crystal; DTA; differential thermal analysis; DSC; differential scanning calorimetry; ÎHc; enthalpy change at Tc; ÎHtr; enthalpy change at Ttr; HLB; hydrophilic/hydrophobic balance; LC; liquid crys
Effects of total saponins from Trillium tschonoskii rhizome on grey and white matter injury evaluated by quantitative multiparametric MRI in a rat model of ischemic stroke
Keywords: TTR; Trillium tschonoskii rhizome; TSTT; total saponins from Trillium tschonoskii rhizome; HPLC; high performance liquid chromatography; MCAO; middle cerebral artery occlusion; MRI; magnetic resonance imaging; T2WI; T2-weighted imaging; MSME; multi-slice
Tumor-promoting cyanotoxin microcystin-LR does not induce procarcinogenic events in adult human liver stem cells
Keywords: HL1-hT1; Microcystin-LR; Adult liver stem cells; Liver tumor-promotion; OATP; Multidrug resistance proteins; AB; Alamar Blue; AFP; α-fetoprotein; ALB; albumin; BCRP; breast cancer resistance protein; BSP; bromosulfophthalein; CFDA-AM; 5-carboxyfluorescei
Serum proteome mapping of EGF transgenic mice reveal mechanistic biomarkers of lung cancer precursor lesions with clinical significance for human adenocarcinomas
Keywords: 2-DE; two-dimensional gel-electrophoresis; AC; adenocarcinoma; A2M; α-2-macroglobulin; AAH; atypical adenomatous hyperplasia; AAT; α-1-antitrypsin; ApoA1; apolipoprotein A-I; ApoA4; apolipoprotein A-IV; ApoC3; apolipoprotein C-III; ApoE; apolipoprotein
Acquired transthyretin amyloidosis after domino liver transplant: Phenotypic correlation, implication of liver retransplantation
Keywords: ATTRm; mutated transthyretin amyloidosis; DLT; Domino liver transplant; EF; ejection fraction; GI; Gastrointestinal; IVS; Interventricular septum; LV; left ventricle; MS/MS; tandem mass spectrometry; OLT; Orthotopic liver transplantation; TTR; Transthyret
Effects of polychlorinated biphenyls on metamorphosis of a marine fish Japanese flounder (Paralichthys olivaceus) in relation to thyroid disruption
Keywords: TDCs; thyroid-disrupting chemicals; PAHs; polycyclic aromatic hydrocarbons; PCBs; polychlorinated biphenyls; THs; thyroid hormones; TTR; transthyretin; TU; thiourea; T4; thyroxine; TCDD; tetrachlorodibenzo-p-dioxin; PCB 126; 3, 3â², 4, 4â², 5-pentachlor
Decapitation improves the efficiency of Cd phytoextraction by Celosia argentea Linn
Keywords: Decapitation; Apical dominance; Phytoextraction; Cadmium; Celosia argentea Linn; DP; decapitated plants; UDP; undecapitated plants; PR; photosynthesis rate; TR; transpiration rate; LA; leaf area; TTR; total transpiration per plant; LSD; least significant
Developmental toxicity and thyroid hormone-disrupting effects of 2,4-dichloro-6-nitrophenol in Chinese rare minnow (Gobiocypris rarus)
Keywords: 2,4-D; 2,4-dichlorophenoxyacetic acid; DCNP; 2,4-dichloro-6-nitrophenol; DCP; 2,4-dichlorophenol; Dio; deiodinase; Dpf; days post-fertilization; EDCs; endocrine-disrupting chemicals; ELISA; enzyme-linked immunosorbent assay; GC-MS; gas chromatography/ma
Hydroxylated polychlorinated biphenyl metabolites (OH-PCBs), maternal smoking and size at birth
Keywords: CHDS; Child Health and Development Studies; PCB; polychlorinated biphenyl; OH-PCB; hydroxylated polychlorinated biphenyl; FT4; free thyroxine; TSH; thyroid stimulating hormone; TTR; transthyretin; 95% CI; 95% confidence interval; ref; reference category;
Magnetic Resonance in Transthyretin Cardiac Amyloidosis
Keywords: ATTR; extracellular volume fraction; late gadolinium enhancement; left ventricular hypertrophy; N-terminal pro-B-type natriuretic peptide; 99m Tc-DPD; 99mTc-3,3-diphosphono-1,2-propanodicarboxylic acid; AL; light-chain amyloidosis; ATTR; transthyretin amy
The interrelationship between bile acid and vitamin A homeostasis
Keywords: ATGL; Adipose triglyceride lipase; ADH; Alcohol dehydrogenase; ALD; Alcoholic liver disease; atRA; All-trans retinoic acid; ASBT/SLC10A2; Apical sodium-dependent bile salt transporter; ABCA1; ATP-binding cassette transporter member 1; BCMO1; Beta-carotene
Therapeutic applications of thyroid hormone analogues in resistance to thyroid hormone (RTH) syndromes
Keywords: Thyroid hormone; Thyroid hormone analogues; Resistance to thyroid hormone; RTH-Beta; AHDS; MCT8; Triac; Tetrac; DITPA; TH; thyroid hormone; T3; 3,3â²,5-triiodothyronine; TR; T3-receptors; RTH; resistance to thyroid hormone; Triac; 3,3â²,5-triiodothyroac
Hepatic maturation of human iPS cell-derived hepatocyte-like cells by ATF5, c/EBPα, and PROX1 transduction
Keywords: Human induced pluripotent stem cells; Hepatocyte; Drug metabolism; ATF5; c/EBPα; PROX1; Human iPS-HLCs; Human induced pluripotent stem cells-derived hepatocyte-like cells; HLCs; Hepatocyte-like cells; ATF5; Activating transcription factor 5; c/EBPα; CCA
Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues
Keywords: 2,4,6-TBP; 2,4,6-tribromophenol; BFR; brominated flame retardant; DI; deiodinase; GC/ECNI-MS; electron capture negative ion mass spectrometry; HIPS; high-impact polystyrene; LC-MS/MS; liquid chromatography tandem mass spectrometry; PBDE; polybrominated
El volumen extracelular detecta la amiloidosis cardiaca y está correlacionado con el deterioro neurológico en la amiloidosis familiar relacionada con la transtiretina
Keywords: Amiloide; Transtiretina; Resonancia magnética cardiaca; Volumen cardiaco extracelular; Mapeo T1; Amyloid; Transthyretin; Cardiac magnetic resonance; Extracellular cardiac volume; T1-mapping; AC; amiloidosis cardiaca; PAF; polineuropatÃa amiloide familia
Extracellular Volume Detects Amyloidotic Cardiomyopathy and Correlates With Neurological Impairment in Transthyretin-familial Amyloidosis
Keywords: Amyloid; Transthyretin; Cardiac magnetic resonance; Extracellular cardiac volume; T1-mapping; Amiloide; Transtiretina; Resonancia magnética cardiaca; Volumen cardiaco extracelular; Mapeo T1; AC; amyloidotic cardiomyopathy; CMR; cardiac magnetic resonance
AL (Light-Chain) Cardiac Amyloidosis
Keywords: cardiomyopathy; multiple myeloma; TTR amyloidosis; AL amyloidosis; light-chain amyloidosis; ATTR amyloidosis; transthyretin amyloidosis; ATTRm amyloidosis; mutant transthyretin amyloidosis; ATTRwt; wild-type transthyretin amyloidosis; CMR; cardiac magneti
Stroke prevention using dabigatran in elderly Chinese patients with atrial fibrillation
Keywords: AF; atrial fibrillation; CHA2DS2-VASc; congestive heart failure (1 point), hypertension (1 point), age 65-74 years (1 point) and age â¥75 years (2 points), diabetes mellitus (1 point), prior stroke or transient ischemic attack (2 points), vascular dise
Suppressing Pitx2 inhibits proliferation and promotes differentiation of iHepSCs
Keywords: Pitx2; paired like homeodomain transcription factor 2; iHepSCs; induced hepatic stem cells; shRNA; small hairpin RNA; Alb; albumin; DAPI; 4â²6-diamidino-2-phenylindole; DiI-ac-LDL; DiI-labelled acetylated low-density lipoprotein; Aat; α-anti-trypsin; Tt
“Tasting” the cerebrospinal fluid: Another function of the choroid plexus?
Keywords: CNS; central nervous system; CP; choroid plexus; CPEC; CP epithelial cells; DMEM; Dulbecco's modified Eagle medium; FBS; fetal bovine serum; GPCRs; G protein-coupled receptors; ICC; immunocytochemistry; IF; immunofluorescence; IHC; immunohistochemistry;
Modulating inhibitors of transthyretin fibrillogenesis via sulfation: Polychlorinated biphenyl sulfates as models
Keywords: ANS; 8-anilinonaphthalene-1-sulfonate; FAC; familial amyloid cardiomyopathy; FAP; familial amyloid polyneuropathy; HBP; halogen binding pocket; OHPCB; hydroxyl-PCB; PCB; polychlorinated biphenyl; SSA; senile systemic amyloidosis; T4; thyroxine; TTR; trans
Assessment of Degree of Anticoagulation Control in Patients With Atrial Fibrillation in Primary Health Care in Galicia, Spain: ANFAGAL Study
Keywords: Nonvalvular atrial fibrillation; Anticoagulation; Primary health care; Fibrilación auricular no valvular; Anticoagulación; Atención primaria; AF; atrial fibrillation; TTR; time in therapeutic range; VKA; vitamin K antagonist;
Direct Oral Anticoagulants in Patients With VTE and Cancer
Keywords: CLOT; Comparison of Low-Molecular-Weight Heparin vs Oral Anticoagulant Therapy for Long-Term Anticoagulation in Cancer Patients With Venous Thromboembolism; DOA; direct oral anticoagulant; LMWH; low-molecular-weight heparin; RCT; randomized clinical trial
A review on the effects of PBDEs on thyroid and reproduction systems in fish
Keywords: PBDEs; polybrominated diphenyl ethers; HPT; hypothalamic-pituitary-thyroid; THs; thyroid hormones; TRs; thyroid receptors; BFRs; brominated flame retardants; cyp19a; cytochrome P450 aromatase A; 11β-hsd; 11β-hydroxysteroid dehydrogenase; PCBs; polyc
Promyelocytic leukemia protein induces arsenic trioxide resistance through regulation of aldehyde dehydrogenase 3 family member A1 in hepatocellular carcinoma
Keywords: HCC; hepatocellular carcinoma; ATO; arsenic trioxide; APL; acute promyelocytic leukemia; PML; promyelocytic leukemia protein; RARα; retinoic acid receptor α; ALDH3A1; aldehyde dehydrogenase 3 family member A1; qRT-PCR; quantitative real-time reverse tra