Keywords: ADP; adenosine diphosphate; ASA; aspirin; CLI; critical limb ischemia; DAPT; dual antiplatelet therapy; DES; drug-eluting stent; DM; diabetes mellitus; HPR; high on-treatment platelet reactivity; HPRA; high on-treatment platelet reactivity to aspirin; HPR
مقالات ISI (ترجمه نشده)
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Keywords: NSAIDs; non steroidal anti-inflammatory drugs; COX; cyclooxygenase; PGs; prostaglandins; AA; arachidonic acid; LO; lipoxygenase; TXA2; thromboxane A2; DS; diclofenac sodium; PLA; poly lactic acid; poly D,L glycolide; PLG; poly lactide-co-glycolide; PLGA;
Keywords: AA; arachidonic acid; AM; acetoxymethyl; CalDAG-GEFI; calcium- and DAG-regulated guanine nucleotide exchange factor 1; COX; cyclooxygenase; DAG; diacylglycerol; FITC; fluorescein isothiocyanate; FSC; forward scatter; GS; stimulatory G-protein; IP3; inosit
Keywords: ADP; adenosine diphosphate; APC; activated protein C; AT-III; antithrombin III; ATP; adenosine triphosphate; cAMP; cyclic adenosine monophosphate; CLP; cecal ligation - perforation; DIC; disseminated intravascular coagulation; LPS; lipopolysaccharide; IL-
Keywords: MD; Mediterranean diet; HT; hydroxytyrosol; IUPAC; International Union of Pure and Applied Chemistry; ADME; absorption, distribution, metabolism and excretion processes; EVOO; extra virgin olive oil; HTA; HT acetate; Tyr; tyrosol; EFSA; European Food Safe
Keywords: 15-PGDH; 15-hydoxyprostaglandin dehydrogenase; AA; arachidonic acid; AF; atrial fibrillation; AKI; acute kidney injury; Akt; alpha serine/threonine-protein kinase; ALA; alpha-linolenic acid; AMD; age-related macular degeneration; Ang II; angiotensin II; B
Keywords: ADP/ATP; adenosine di/tri phosphate; ApL; antiphospholipid; BTG; beta-thrombomodulin; COX; cycloâoxygenase; CVD; cardiovascular disease; DAMP; damage-associated molecular patterns; EC; endothelial cells; ECM; extracellular matrix; ET-1; endothelin-1; HC
Keywords: Antiplatelet; Preclinical studies; Structure-activity relationship (SAR) studies; Pharmacokinetic parameters; Safety profile; AA; arachidonic acid; ADP; adenosine diphosphate; ATP; adenosine triphosphate; CNS; central nervous system; COX-1; cyclooxygenase
Keywords: ALA; α-lipoic acid; AMPK; AMP-activated protein kinase; eNOS; endothelial NO synthase; ECM; extracellular matrix; ET-1; endothelin-1; EVs; extracellular vesicles; HCS; Hepatic stellate cells; HI; intermittent hypoxia; NO; nitric oxide; NAFLD; nonalcoholi
Keywords: Cyclooxygenase; Tectorigenin; Isoflavones; Platelets; AA; arachidonic acid; ASA; acetylsalicylic acid; COX-1; cyclooxygenase-1; EDTA; ethylendiamintetraacetic acid; PRP; platelet rich plasma; PPP; platelet poor plasma; TXA2; thromboxane A2;
Keywords: AML; acute myeloid leukemia; MUFA; monounsaturated fatty acid; CML; chronic myelogenous leukemia; ALL; acute lymphoblastic leukemia; FAO; fatty acid oxidation; CPT1a; carnitine palmitate transferase 1a; SCD1; stearoyl CoA desaturase 1; FAB; French-America
Keywords: CAD; coronary artery diseases; DIC; disseminated intravascular coagulation, I/R, ischemia/reperfusion; MPI; myocardial perfusion imaging; SCI; spinal cord injury; ED; erectile dysfunction; AUC; area under the concentration-time curve; cAMP; cyclic adenosi
Keywords: ADP; adenosine 5â²-diphisphate; COX; cyclooxygenase; CYP; cytochromes P450; GP; glycoprotein; IP3; inositol triphosphate; PFA-100; platelet function analyzer; PSGL-1; P-selectin glycoprotein ligand-1; sCD40L; subule CD40 ligand; TXA2; thromboxane A2; vWF
Keywords: Health claims; Claimed effect; Outcome variable; Method of measurement; Oxidative damage; Cardiovascular health; 8-OHdG; 8-hydroxy-2-deoxy-guanosine; 8-oxo-dG; 8-oxo-2-deoxyguanosine; ABPM; Ambulatory blood pressure monitoring; ADP; Adenosine diphosphate;
Keywords: ATP; adenosine triphosphate; CABG; coronary artery bypass grafting surgery; cAMP; cyclic adenosine monophosphate; cGMP; cyclic guanosine monophosphate; ET; endothelin-1; GEA; gastroepiploic artery; IMA; internal mammary artery; KCO; potassium-channel open
Keywords: ADP; adenosine diphosphate; ANOVA; analysis of variance; APC; allophycocyanin; aPTT; activated partial thromboplastin time; COX-1; cyclooxygenase-1; CVD; cardiovascular disease; C3GE; cyanidin-3-glucoside equivalents; FBC; full blood count; FITC; fluoresc
Keywords: Alpha-linolenic acid (PubChem CID: 5280934); Enterodiol (PubChem CID: 123725); Enterolactone (PubChem CID: 114739); Secoisolariciresinol diglucoside (PubChem CID: 9917980); AA; arachidonic acid; ALA; alpha-linolenic acid; AV; acid value; CD; conjugated di
Keywords: 5-HT; 5-hydroxytryptamine; ATS; atherosclerosis; ATII; angiotensin II; CABG; coronary artery bypass graft; ET; endothelin; ITA; internal thoracic artery; LD; luminal diameter; NO; nitric oxide; RA; radial artery; SV; saphenous vein; TXA2; thromboxane A2;
Keywords: COX-1; cyclooxygenase-1; AA; arachidonic acid; TXA2; thromboxane A2; acCOX-1; acetylated COX-1; nacCOX-1; non-acetylated COX-1; TXB2; thromboxane B2; PRP; Platelet rich plasma; VN Aspirin Assay; VerifyNow® Aspirin assay; PDP; Platelet depleted plasma; an
Keywords: 16; 23; 38; ADP; adenosine diphosphate; APT; antiplatelet therapy; BOCLA-Plan; BOchum CLopidogrel and Aspirin Plan; CABG; coronary artery bypass grafting; CI; confidence interval; CYP; cytochrome P450; dAPT; dual antiplatelet therapy; HR; hazard ratio; hR
Keywords: ADP; adenosine 5â²-diphosphate; AA; arachidonic acid; CLA; conjugated linoleic acid; COX-1; cyclooxygenase-1; CVD; cardiovascular disease; DHA; docosahexaenoic acid; EFSA; European Food Safety Authority; EPA; eicosapentaenoic acid; GP; glycoprotein; ICAM
Keywords: ADSC; adipose derived stem cell; AFM; atomic force microscopy; ALP; alkaline phosphatase; BMP; bone morphogenetic protein; BMSC; bone marrow stem cells; Ca3P2O8; tricalcium orthophosphate; DMEM; Dulbecco modified Eagle's medium; ECM; extracellular matrix;
Keywords: I/R; ischemia-reperfusion; LSEC; liver sinusoidal endothelial cells; KC; Kupffer cells; HSC; hepatic stellate cells; NAD; nicotinamide adenine dinucleotide; ROS; reactive oxygen species; NO; nitric oxide; ET; endothelin; TXA2; thromboxane A2; KLF2; Kruppe
The toxic effects of monosodium glutamate (MSG) - The involvement of nitric oxide, prostanoids and potassium channels in the reactivity of thoracic arteries in MSG-obese rats
Keywords: Monosodium glutamate; Nitric oxide; Obesity; Potassium channels; Thromboxane A2; A23187; calcium ionophore; BKCa; Large Conductance Ca2+-activated K+ channels; cGMP; cyclic guanosine monophosphate; COX; cyclooxygenase; EDCF; endothelial derived contractin
Effects of Danhong Injection on platelet aggregation in hyperlipidemia rats
Keywords: DHI; Danhong Injection; 6-keto-PGF1a; 6-keto-prostaglandin F1a; TG; triglyceride; TC; total cholesterol; LDL-C; low density lipoprotein cholesterol; HDL-C; high density lipoprotein cholesterol; PAF; platelet activating factor; GP IIb/IIIa; platelet membra
Prostaglandin-endoperoxide synthase 2 (cyclooxygenase-2), a complex target for colorectal cancer prevention and therapy
Keywords: PTGS; prostaglandin-endoperoxide synthase; COX-2; cyclooxygenase-2; CRC; colorectal cancer; NSAIDs; nonsteroidal antiinflammatory drugs; ILF; isolated lymphoid follicles; ACF; aberrant crypt foci; DMH; dimethylhydrazine; PGE2; prostaglandin E2; FAP; famil
Effects of the NO/soluble guanylate cyclase/cGMP system on the functions of human platelets
Keywords: Platelet inhibition; Phosphoproteome; cGMP-dependent protein kinase/PKG; Small GTP-binding proteins; G proteins; NO; nitric oxide; PKA; protein kinase A; PKG; protein kinase G; PDE; phosphodiesterase; sGC; soluble guanylate cyclase; GPCR; G-protein couple
Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells
Keywords: PTMs; post-translational modifications; PAMPs; pathogen-associated molecular patterns; TLRs; Toll-like receptors; HUVEC; human umbilical vein endothelial cells; AMPK; AMP-activated protein kinase; Akt; serine/thPGI2, prostacyclin; TXA2; thromboxane A2; CO
Inflammatory mediators mediate airway smooth muscle contraction through a G protein-coupled receptor-transmembrane protein 16A-voltage-dependent Ca2+ channel axis and contribute to bronchial hyperresponsiveness in asthma
Keywords: Airway smooth muscle; asthma; hypersensitivity; inflammatory mediator; TMEM16A; 5-HT; 5-Hydroxytryptamin; Ai38D; Cre-dependent GCaMP3 reporter mouse; ASM; Airway smooth muscle; ASMC; Airway smooth muscle cell; ClCa; Ca2+-activated Clâ; CTR; Control; GCa
Full Length ArticleInhibitory effects of ASP6537, a selective cyclooxygenase-1 inhibitor, on thrombosis and neointima formation in rats
Keywords: COX; cyclooxygenase; TXA2; thromboxane A2; I/M ratio; intima/media ratio; Platelets; Cyclooxygenase-1; Acetylsalicylic acid; Thrombosis; Neointima formation;
Ceramide enhances COX-2 expression and VSMC contractile hyperreactivity via ER stress signal activation
Keywords: COX-2; cyclooxygenase-2; PE; phenylephrine; ER; Endoplasmic reticulum; 4-BPA; 4-phenyl butyric acid; TUDCA; Tauroursodeoxycholic Acid Sodium; PGE2; prostaglandin E2; PGI2; prostaglandin I2; TxA2; thromboxane A2; Ceramide; ER stress; COX-2; Vasoconstrictio
Identification, signaling, and functions of LTB4 receptors
Keywords: AA; arachidonic acid; CLDN4; claudin-4; COX; cyclooxygenase; DGS3; desmoglein-3; DSS; dextran sodium sulfate; 5-LOX; 5-lipoxygenase; 5(S)-HETE; 5(S)-hydroxy-6E,8Z,11Z,14Z-eicosatetraenoic acid; 5(S)-HpETE; 5(S)-hydroperoxy-6E,8Z,11Z,14Z-eicosatetraenoic a
Regulation of protein kinase C-related kinase (PRK) signalling by the TPα and TPβ isoforms of the human thromboxane A2 receptor: Implications for thromboxane- and androgen- dependent neoplastic and epigenetic responses in prostate cancer
Keywords: ADT; androgen deprivation therapy; AR; androgen receptor; ARE; androgen response element; AA; arachidonic acid; BCR; biochemical recurrence; ChIP; chromatin immunoprecipitation; COX; cyclooxygenase/prostaglandin G2/H2 synathase; CRPC; castrate resistant p
Introduction of β-d-mannuronic acid (M2000) as a novel NSAID with immunosuppressive property based on COX-1/COX-2 activity and gene expression
Keywords: ANOVA; analysis of variance; AA; arachidonic acid; BUN; blood urea nitrogen; COX; cyclooxygenase; EAE; experimental autoimmune encephalomyelitis; IRAK1; interleukin-1 receptor-associated kinase 1; LPS; lipopolysaccharide; LPS-EB; LPS from E. coli O111: B4
DioxolaneA3-phosphatidylethanolamines are generated by human platelets and stimulate neutrophil integrin expression
Keywords: DXA3; 8-hydroxy-9, 10-dioxolane A3; PE; phosphatidylethanolamine; COX; cyclooxygenase; PAR; protease-activated receptors; cPLA2; cytosolic phospholipase A2; TXA2; thromboxane A2; HETE; hydroxyeicosatetraenoic acid; PGE2; prostaglandin E2; OOEPC; oleyloxye
GPVI and Thromboxane Receptor on Platelets Promote Proinflammatory Macrophage Phenotypes during Cutaneous Inflammation
Keywords: CD62P; P-selectin; GPVI; glycoprotein VI; PGE2; prostaglandin E2; TP; thromboxane receptor; TXA2; thromboxane A2;
1, 6-di-O-caffeoyl-β-D-glucopyranoside, a natural compound from Callicarpa nudiflora Hook impairs P2Y12 and thromboxane A2 receptor-mediated amplification of platelet activation and aggregation
Keywords: Platelet activation; P2Y12 receptor; TP receptor; Callicarpa nudiflora; 1, 6-di-O-caffeoyl-β-D-glucopyranoside; 5-HT; 5-serotonin; AA; Arachidonic acid; ADP; Adenosine diphosphate; AP; Alkaline phosphatase; CGP; 1, 6-di-O-caffeoyl-β-D-glucopyranoside; C
Regulated expression of the TPβ isoform of the human T prostanoid receptor by the tumour suppressors FOXP1 and NKX3.1: Implications for the role of thromboxane in prostate cancer
Keywords: 5-aza-dC; 5-aza-2â²-deoxycytidine; AA; arachidonic acid; ADT; androgen deprivation therapy; AR; androgen receptor; BCR; biochemical recurrence; ChIP; chromatin immunoprecipitation; CNA; copy number alteration; COX; cyclooxygenase/prostaglandin G2/H2 synt
Lipidomics in translational research and the clinical significance of lipid-based biomarkers
Keywords: 5-HETE; 5-hydroxyicosatetraenoic acid; 12-HETE; 12-hydroxyicosatetraenoic acid; 15-HETE; 15-hydroxyicosatetraenoic acid; aa; diacyl; ae; acyl-alkyl; ACs; acylcarnitines; ACOG; The American College of Obstetricians and Gynecologists; AD; Alzheimer's dise
The key residue within the second extracellular loop of human EP3 involved in selectively turning down PGE2- and retaining PGE1-mediated signaling in live cells
Keywords: EP selectivity; G protein-coupled receptor (GPCR); Prostaglandin; Prostaglandin E1; Prostaglandin E2; Receptor regulation; AA; arachidonic acid; COX-1 and -2; cyclooxygenase-1 and -2, respectively; cPGES; cytosolic PGES; DGLA; dihomo-γ-linolenic acid; EP
Simultaneous quantification of PGI2 and TXA2 metabolites in plasma and urine in NO-deficient mice by a novel UHPLC/MS/MS method
Keywords: PGI2; prostacyclin; TXA2; thromboxane A2; IP; PGI receptor; TP; TX receptor; PLA2; phospholipase A2; PGIS; prostacyclin synthase; TXS; thromboxane A synthase; UHPLC/MS/MS; ultra high-performance liquid chromatography coupled to mass spectrometry; TXB2; th
Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1
Keywords: Arachidonic acid; Cyclooxygenase-2; Microsomal prostaglandin E2 synthase; Polyunsaturated fatty acid; Prostaglandin E2; 10aa; 10 amino acid residues; AA; arachidonic acid; CHD; coronary heart disease; COX-1 and -2, respectively; cyclooxygenase-1 and -2; c
In vitro inhibition of platelet aggregation by peptides derived from oat (Avena sativa L.), highland barley (Hordeum vulgare Linn. var. nudum Hook. f.), and buckwheat (Fagopyrum esculentum Moench) proteins
Keywords: AA; arachidonic acid; ASA; acetylsalicylic acid; COX1; cyclooxygenase-1; NS; normal saline; PPP; platelet-poor plasma; PRP; platelet-rich plasma; TXA2; thromboxane-A2; TXB2; thromboxane-B2; WP; washed platelet; GO; gastrointestinal hydrolysate of oat flou
In vitro pharmacological evaluation of multitarget agents for thromboxane prostanoid receptor antagonism and COX-2 inhibition
Keywords: AA; arachidonic acid; CV; cardiovascular; COX; cyclooxygenase coxibs; COX-2; selective inhibitors; DMEM; Dulbecco's modified eagle's medium; EIA; enzyme immunoassay; IP; inositol phosphate; HEK293; human embryonic kidney 293; NSAID; nonsteroidal anti-
Rat aorta as a pharmacological tool for in vitro and in vivo studies
Keywords: BH4; tetrahydrobiopterin; cGMP; cyclic guanine monophosphate; COX; cyclooxygenase; cNOS; constitutive NOS; DAG; diacylglycerol; DMEM; Dulbecco's modified eagle's medium; eNOS; endothelial NOS; EDHF; endothelium dependent hyperpolarization factor; EGTA; et
Stauntoside B inhibits macrophage activation by inhibiting NF-κB and ERK MAPK signalling
Keywords: NO; nitric oxide; PGE2; prostaglandin E2; NSAIDs; non-steroidal anti-inflammatory drugs; qRT-PCR; quantitative real-time polymerase chain reaction; LPS; lipopolysaccharide; IFN-γ; interferon γ; G-CSF; granulocyte colony stimulating factor; TNF-α; tumor
Gasomediators (·NO, CO, and H2S) and their role in hemostasis and thrombosis
Keywords: ADP; adenosine diphosphate; CAT; cysteine aminotransferase; CBS; cystathionine β-synthase; cGMP; cyclic guanosine monophosphate; CO; carbon monoxide; CORM; CO-releasing molecule; CSE; cystathionine γ-lyase; GC-MS; gas chromatography-mass spectrometry; e
Human EP2 prostanoid receptors exhibit more constraints to mutations than human DP prostanoid receptors
Keywords: DP; D-type prostanoid; EP; E-type prostanoid; PGE2; prostaglandin E2; PGD2; prostaglandin D2; FP; F-type prostanoid; PGF2α; prostaglandin F2α; IP; I-type prostanoid; PGI2; prostaglandin I2; TP; T-type prostanoid; TXA2; thromboxane A2; CRTH2; chemo-attra
N2 extenuates experimental ischemic stroke through platelet aggregation inhibition
Keywords: N2; 4-(2-(1Â H-imidazol-1-yl) ethoxy)-3-methoxybenzoic acid; NS; 0.9% sodium chloride; ADP; adenosine diphosphate; PLA2; phospholipase A2; MCAO; middle cerebral artery occlusion; MCAO/R; middle cerebral artery occlusion/reperfusion; AA; arachidonic acid;
SDF-1α is a novel autocrine activator of platelets operating through its receptor CXCR4
Keywords: SDF-1α; stromal cell-derived factor-1α; CXCR4; CXC chemokine receptor type 4; CXCR7; CXC chemokine receptor type 7; PRP; platelet-rich plasma; TxA2; thromboxane A2; GPCR; G-protein-coupled receptor; PGE1; prostaglandin E1; AR-C-66096; AR-C; Platelet; Th