دانلود مقالات ISI درباره سیستم ubiquitin-proteasome + ترجمه فارسی

Myostatin/activin pathway antagonism: Molecular basis and therapeutic potential

Keywords: سیستم ubiquitin-proteasome; Myostatin/activin-ActRIIB signaling pathway; Ubiquitin-proteasome system; Ubiquitin ligases; Protein breakdown; Muscle wasting diseases;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2013 سفارش ترجمه

Proteomics identifies ubiquitin-proteasome targets and new roles for chromatin-remodeling in the Arabidopsis response to phosphate starvation

Keywords: سیستم ubiquitin-proteasome; Phosphate starvation; Phosphate signaling; Nuclear proteome; Ubiquitin-proteasome system; NAP1;2; Histone chaperone; DIGE; Arabidopsis;

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2013 سفارش ترجمه

The immunoproteasome β5i subunit is a key contributor to ictogenesis in a rat model of chronic epilepsy

Keywords: سیستم ubiquitin-proteasome; 4-AP; 4-aminopyridine; Ach; acetylcholine; ACSF; artificial cerebrospinal fluid; CNS; central nervous system; i-proteasome; immunoproteasome; HMGB1; High Mobility Group Box-1; LPS; lipopolysaccharide; MCA; 7-amino-4-methylcoumarin; s-proteasome; standard

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Regulation of p97 in the ubiquitin-proteasome system by the UBX protein-family

Keywords: سیستم ubiquitin-proteasome; VCP; valosin-containing protein; AAA; ATPase associated with various cellular activities; UBX; ubiquitin-regulatory X; UPS; ubiquitin-proteasome system; ERAD; endoplasmic reticulum-associated degradation; UBX-L; UBX-like; Npl4; nuclear protein localizat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2012 سفارش ترجمه

NMR characterization of the interaction between the PUB domain of peptide:N-glycanase and ubiquitin-like domain of HR23

Keywords: سیستم ubiquitin-proteasome; PUB domain; Peptide:N-glycanase; HR23; NMR; Endoplasmic reticulum-associated degradation; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2012 سفارش ترجمه

Research ReportZinc neurotoxicity to hippocampal neurons in vitro induces ubiquitin conjugation that requires p38 activation

Keywords: سیستم ubiquitin-proteasome; Zn; zinc; UPS; ubiquitin-proteasome system; Neuron; Ubiquitin; Zinc; Traumatic brain injury; p38;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Biosynthetic mode can determine the mechanism of protein quality control

Keywords: سیستم ubiquitin-proteasome; Endoplasmic reticulum; Protein quality control; Protein degradation; Protein folding; Ubiquitin-proteasome system; Membrane protein; ERAD;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2012 سفارش ترجمه

Scaffold protein Homer 1: Implications for neurological diseases

Keywords: سیستم ubiquitin-proteasome; EVH1; Enabled/vasodilator-stimulated phosphoprotein (Ena/VASP) homology 1; IEG; immediate-early gene; P motif; proline-containing motif; mGluR; metabotropic glutamate receptor; IP3R; inositol 1,4,5-trisphosphate receptor; TRPC; transient receptor potentia

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2012 سفارش ترجمه

SIRT2 interferes with autophagy-mediated degradation of protein aggregates in neuronal cells under proteasome inhibition

Keywords: سیستم ubiquitin-proteasome; Aβ; amyloid beta; AD; Alzheimer's disease; BSA; bovine serum albumin; CMA; chaperone-mediated autophagy; DMEM; Dulbecco's modified eagle's medium; ECL; enhanced chemiluminescence; FBS; fetal bovine serum; HD; Huntington's disease; HDAC; histone d

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2012 سفارش ترجمه

Resveratrol reverses monocrotaline-induced pulmonary vascular and cardiac dysfunction: A potential role for atrogin-1 in smooth muscle

Keywords: سیستم ubiquitin-proteasome; Phytoalexin; Atrogin-1; Smooth muscle hypertrophy; Atrophy; Ubiquitin-proteasome system; Resveratrol;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

Mutant ubiquitin decreases amyloid β plaque formation in a transgenic mouse model of Alzheimer's disease

Keywords: سیستم ubiquitin-proteasome; Alzheimer's disease; Amyloid β; UBB+1; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

DGKζ is degraded through the cytoplasmic ubiquitin-proteasome system under excitotoxic conditions, which causes neuronal apoptosis because of aberrant cell cycle reentry

Keywords: سیستم ubiquitin-proteasome; Diacylglycerol kinase; Excitotoxicity; Ubiquitin-proteasome system; Cell cycle reentry;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2012 سفارش ترجمه

GCK-MODY diabetes associated with protein misfolding, cellular self-association and degradation

Keywords: سیستم ubiquitin-proteasome; Ab; antibody; GK; glucokinase; GKRP; glucokinase regulatory protein; Glc; α-d-glucose; HEK293; human embryonic kidney 293 cells; hGK; human glucokinase; MIN6; mouse insulinoma cell; MODY; maturity-onset diabetes of the young; PDB; protein data bank; PNS;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Crosstalk between the ubiquitin-proteasome system and autophagy in a human cellular model of Alzheimer's disease

Keywords: سیستم ubiquitin-proteasome; AβPP; amyloid-β precursor protein; Aβ40; amyloid-β (1-40); Aβ42; amyloid-β (1-42); UPS; ubiquitin-proteasome system; HDAC6; histone deacetylase 6; ChT-L; chymotrypsin-like; T-L; trypsin-like; PGPH; peptidylglutamyl-peptide hydrolyzing; AP-N; a

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2012 سفارش ترجمه

Engineered antibody therapies to counteract mutant huntingtin and related toxic intracellular proteins

Keywords: سیستم ubiquitin-proteasome; BBB; blood-brain barrier; dAbs; domain antibodies; HD; Huntington's disease; HSC70; heat shock cognate protein 70; HSP70; heat shock protein 70; HTT; huntingtin protein; mHTT; mutant huntingtin protein; PEST; Proline (P), Glutamic Acid (E), Serine (S) a

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2012 سفارش ترجمه

Autophagy and polyglutamine diseases

Keywords: سیستم ubiquitin-proteasome; HD; Huntington's disease; SCA; spinocerebellar ataxia; DRPLA; Denatorubral-pallidoluysian atrophy; SBMA; spinal and bulbar muscular atropy; Htt; Huntingtin; UPS; ubiquitin-proteasome system; HDL-2; Huntington's disease-like 2; IBs; inclusion bodies; RNA

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2012 سفارش ترجمه

Alteration of protein folding and degradation in motor neuron diseases: Implications and protective functions of small heat shock proteins

Keywords: سیستم ubiquitin-proteasome; ALS; amyotrophic lateral sclerosis; AR; androgen receptor; ATG5; autophagy-related gene 5; Bag; Bcl-2 associated athanogene; CBP; CREB-binding protein; CMA; chaperone-mediated autophagy; CMT; Charcot-Marie-Tooth; DAO; d-amino acid oxidase; DCTN1; dynactin

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2012 سفارش ترجمه

Dysfunction of the ubiquitin-proteasome system in the cerebellum of aging Ts65Dn mice

Keywords: سیستم ubiquitin-proteasome; Down syndrome; Cerebellum; Neurodegeneration; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2011 سفارش ترجمه

The prognostic impact of circulating proteasome concentrations in patients with epithelial ovarian cancer

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Extracellular proteasome; Prognosis; Survival;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2011 سفارش ترجمه

Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation

Keywords: سیستم ubiquitin-proteasome; NFs; neurofilaments; HD; 2,5-hexanedione; CHIP; carboxyl-terminus of Hsc70 interacting protein; NF-M; neurofilament medium chain; UPS; ubiquitin proteasome system; IFs; intermediate filaments; CHX; cycloheximide; TPR; tetratricopeptide repeat; UbmE1; ubiq

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Aging and calorie restriction modulate yeast redox state, oxidized protein removal, and the ubiquitin-proteasome system

Keywords: سیستم ubiquitin-proteasome; AMC; 7-amino-4-methylcoumarin; CR; calorie restriction; DTNB; 5,5′-dithiobis-(2-nitrobenzoic acid); DTT; dithiothreitol; GSH; reduced glutathione; GSSG; oxidized glutathione; PVDF; polyvinylidene difluoride; Tris; tris(hydroxymethyl)aminomethane; UPS; u

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Studying protein degradation pathways in vivo using a cranial window-based approach

Keywords: سیستم ubiquitin-proteasome; Cranial window; In vivo; Protein degradation; Ubiquitin-proteasome system; Mouse; Cortex;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2011 سفارش ترجمه

Alzheimer-associated mutant ubiquitin impairs spatial reference memory

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Neurodegeneration; Transgenic mouse model; Mutant ubiquitin; Behavior;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2011 سفارش ترجمه

HSP70 mediates dissociation and reassociation of the 26S proteasome during adaptation to oxidative stress

Keywords: سیستم ubiquitin-proteasome; MEF; murine embryonic fibroblasts; PA28αβ; a proteasome regulator (also called the 11S regulator); Hb; hemoglobin; TCA; trichloroacetic acid; PBS; phosphate-buffered saline; Oxidative stress; Ubiquitin-proteasome system; Protein degradation; Protein o

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2011 سفارش ترجمه

Proteasome inhibitors: Dozens of molecules and still counting

Keywords: سیستم ubiquitin-proteasome; Proteasome; Ubiquitin; Inhibitors; Proteasome inhibitors; AAA; ATPases Associated with various cellular Activities; PI; proteasome inhibitor; MM; Multiple Myeloma; UPS; Ubiquitin-proteasome system; MHC-I; Major Histocompatibility Complex I; CT-L, T-L, C

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Cell-produced α-synuclein oligomers are targeted to, and impair, the 26S proteasome

Keywords: سیستم ubiquitin-proteasome; PD; Parkinson's Disease; αS; α-synuclein; UPS; ubiquitin-proteasome system; PrP; prion protein; WT; wild-type; CTL; control; CT; chymotrypsin; T; trypsin; C; caspase; SEC; size exclusion chromatography; HMW; high molecular weight; LMW; low molecular w

دانلود رایگان متن کامل مقاله ISI 16 صفحه سال انتشار : 2010 سفارش ترجمه

Short communicationTreatment with phosphotidylglycerol-based nanoparticles prevents motor deficits induced by proteasome inhibition: Implications for Parkinson's disease

Keywords: سیستم ubiquitin-proteasome; Parkinson's disease; Ubiquitin-proteasome system; Phosphotidylglycerol; VP025; Rotarod test; Open field test; Dopamine;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2008 سفارش ترجمه

The ubiquitin-proteasome system in cardiac dysfunction

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Cardiomyopathy; Autophagy; Cardiac disease;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2008 سفارش ترجمه

The ubiquitin-proteasome system in spongiform degenerative disorders

Keywords: سیستم ubiquitin-proteasome; AD; Alzheimer's disease; AgRP; Agouti related protein; AIDS; acquired immune deficiency syndrome; APP; amyloid precursor protein; ASPA; aspartoacylase gene; Atrn; attractin; BSE; bovine spongiform encephalopathy; CD; Canavan's spongiform leukodystroph

دانلود رایگان متن کامل مقاله ISI 32 صفحه سال انتشار : 2008 سفارش ترجمه

Glutamate stimulates glutamate receptor interacting protein 1 degradation by ubiquitin-proteasome system to regulate surface expression of GluR2

Keywords: سیستم ubiquitin-proteasome; GRIP1; degradation; glutamate; AMPA receptor; UPS; GluR2; BAPTA; 1,2-bis(2-aminophenoxy)ethane-N,N,N′,N′-tetra acetic acid tetrakis; CNQX; 6-cyano-7-nitroquinoxaline-2,3-dione; EGTA; ethylene glycol-bis(beta-aminoethyl ether)-N,N,N′,N′-tetraacetic

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2007 سفارش ترجمه

Xenobiotic-induced autoimmunity and protein aggregation diseases share a common subnuclear pathology

Keywords: سیستم ubiquitin-proteasome; Autoimmunity; Cell nucleus; Neurodegenerative diseases; Protein degradation; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2005 سفارش ترجمه

The aggravating role of the ubiquitin-proteasome system in neurodegeneration

Keywords: سیستم ubiquitin-proteasome; Ubiquitin; Neurodegeneration; Inclusion; Aggresome; Ubiquitin-proteasome system;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2005 سفارش ترجمه

The transcription factor Sox9 is degraded by the ubiquitin-proteasome system and stabilized by a mutation in a ubiquitin-target site

Keywords: سیستم ubiquitin-proteasome; Sox9; Ubiquitin-proteasome system; Mutagenesis;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2005 سفارش ترجمه

Ubiquitin-proteasome system and Parkinson's diseases

Keywords: سیستم ubiquitin-proteasome; Ubiquitin-proteasome system; Parkinson's disease; Lewy bodies;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2005 سفارش ترجمه