Cellular tolerance of prion protein PrP in yeast involves proteolysis and the unfolded protein response
Keywords: Ubiquitin; ERAD; PrP; UPR; Proteasome
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A conserved role of Caenorhabditis elegans CDC-48 in ER-associated protein degradation
Keywords: CDC48; Caenorhabditis elegans; ERAD; UPR; Ubiquitin
Aberrant trafficking of a proteolipid protein in a mild Pelizaeus-Merzbacher disease
Keywords: Pelizaeus-Merzbacher disease; proteolipid protein; intracellular trafficking; unfolded protein response; BiP; 78-kDa glucose regulated protein/immunoglobulin heavy chain binding protein; CFTR; cystic fibrosis transmembrane conductance regulator; DYT1 dyst
Patterns of tumor oxygenation and their influence on the cellular hypoxic response and hypoxia-directed therapies
Keywords: Hypoxia; Anoxia; Reoxygenation; HIF; UPR; Tumor microenvironment
HACA, the transcriptional activator of the unfolded protein response (UPR) in Aspergillus niger, binds to partly palindromic UPR elements of the consensus sequence 5′-CAN(G/A)NTGT/GCCT-3′
Keywords: Aspergillus niger; UPR; UPRE; hacA; DNA-binding; bZIP; ER stress
Expression of endoplasmic reticulum molecular chaperone Grp78 in human lung cancer and its clinical significance
Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; Grp; glucose-regulated protein; IHC; immunohistochemical; CEA; carcinoembryonic antigen; ATF4; activating transcription factor 4; NSCLC; non-small cell lung cancer; Grp78; Lung cancer; Immunohisto
XBP1 activates the transcription of its target genes via an ACGT core sequence under ER stress
Keywords: XBP1; UPR; ER stress; ACGT core; Transcription; IRE1; cis-element;
GM1-ganglioside degradation and biosynthesis in human and murine GM1-gangliosidosis
Keywords: β-gal; β-galactosidase; β-galâ/â; mouse model of GM1-gangliosidosis; C:M; chloroform:methanol; ER; endoplasmic reticulum; Gal T-II/GM2 β-1,3-galactosyltransferase; GM1 synthase; GlcCer; glycosylceramide; GSL; glycosphingolipid; HMF; hind-, mid- an
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
Keywords: GRP78; UPR; Endoplasmic reticulum;
Dying a Thousand Deaths: Redundant Pathways From Different Organelles to Apoptosis and Necrosis
Keywords: Akt; proto-oncogene product of the viral oncogene v-akt; AIF; apoptosis inducing factor; Apaf-1; apoptotic protease activating factor-1; ATF6; activating transcription factor 6; Bad; heterodimeric partner for Bcl-xL and Bcl-2; Bak; Bcl2 homologous antagon
The protective effect of dantrolene on ischemic neuronal cell death is associated with reduced expression of endoplasmic reticulum stress markers
Keywords: Disorders of the nervous system; Ischemia; ANOVA; one-way analyses of variance; ATF-4; activating transcription factor-4; Ca2+; calcium ions; CBF; cerebral blood flow; CHOP; C/EBP-homologous protein; D; dantrolene treatment; DMSO; dimethyl sulfoxide; eIF2
Gpi17p does not stably interact with other subunits of glycosylphosphatidylinositol transamidase in Saccharomyces cerevisiae
Keywords: BCS; bathocuproinedisulfonic acid; GPI; glycosylphosphatidylinositol; NP-40; Nonidet P-40; TMD; transmembrane domain; UPR; unfolded protein response; wt; wild type; GPI17; Glycosylphosphatidylinositol; Transamidase; Saccharomyces; Protein stability; Unfol
Renal ischemia and reperfusion activates the eIF2 alpha kinase PERK
Keywords: ER; endoplasmic reticulum; eIF2α; alpha subunit of eukaryotic initiation factor-2; ischemia and reperfusion; I/R; PERK; PKR-like ER eIF2α kinase; tg; thapsigargin; UPR; unfolded protein response; Renal ischemia and reperfusion; eIF2α(P); Endoplasmic re
Hepatic mitochondrial glutathione: transport and role in disease and toxicity
Keywords: ALD; alcohol-induced liver disease; APAP; N-acetyl-p-aminophenol; ASMase; acidic sphingomyelinase; CYP2E1; cytochrome P450 2E1; DISC; death-inducing signaling complex; ER; endoplasmic reticulum; GSH; reduced glutathione; GSSG; oxidized glutathione; HMGCoA
Transcriptional profiling of mefloquine-induced disruption of calcium homeostasis in neurons in vitro
Keywords: Mefloquine; Thapsigargin; Microarrays; Neurotoxicity; UPR; Transcription factors;
Cellular abnormalities linked to endoplasmic reticulum dysfunction in cerebrovascular disease-therapeutic potential
Keywords: Degenerative diseases; Endoplasmic reticulum; Ischemia; Stroke; Unfolded protein response; 4-PBA; 4-phenylbutyric acid; Aβ; amyloidogenic β-peptide; ATF; activating transcription factor; eIF2α; alpha subunit of the eukaryotic initiation factor 2; ER; e
ER stress signaling by regulated splicing: IRE1/HAC1/XBP1
Keywords: UPR; unfolded protein response; ER; endoplasmic reticulum; IRE1; Hac1; XBP1; X-box binding protein 1;