دانلود مقالات ISI درباره Upr + ترجمه فارسی

Mcl-1 downregulation leads to the heightened sensitivity exhibited by BCR-ABL positive ALL to induction of energy and ER-stress

Keywords: Leukemia; BCR-ABL+; 2-deoxy-d-glucose; ER stress; Energy stress; UPR; Imatinib; Dasatinib; ERK; Mcl-1; AMPK; eIF2α; shRNA; Apoptosis; Tyrosine kinase inhibitors; Combination targeted therapy; Acute lymphoblastic leukemia;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

The role of AGR2 and AGR3 in cancer: Similar but not identical

Keywords: AGR2; AGR3; PDI family; Cancer; AA; amino acids; ALS; familial amyotrophic lateral sclerosis; AGR; anterior gradient; AhR; aryl hydrocarbon receptor; AR; androgen receptor; CAPN8; calpain 8; CAPN9; calpain 9; CDDP; cisplatin; CFTR; cystic fibrosis transme

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Resistin: Insulin resistance to malignancy

Keywords: ER; endoplasmic reticulum; HDL; high density lipoprotein; IL; interleukin; IR; insulin resistance; JAK/STAT; Janus kinase/signal transducer and activator of transcription; LDL; low density lipoprotein; MAPK; mitogen-activated protein kinase; MetS; metabol

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Quality control mechanisms in cellular and systemic DNA damage responses

Keywords: DNA damage; Ageing; Ubiquitin proteasome system; DNA repair; Progeroid syndromes; Genome stability; ARF; adenosine diphosphate ribosylation factor; AT; ataxia telangiectasia; ATM; ataxia telangiectasia mutated; ATP; adenosine triphosphate; BER; base excis

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Activated AMPK boosts the Nrf2/HO-1 signaling axis-A role for the unfolded protein response

Keywords: ACC; acetyl-CoA carboxylase; AMPK; AMP-activated kinase; ARE; antioxidant response element; βTrcP1; β-transducin-repeat containing protein 1; CaMKK; calcium calmodulin-dependent kinase kinase; CHO; Chinese hamster ovary; DCF; dichlorofluorescein; DMSO;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2015 سفارش ترجمه

Tunicamycin-induced unfolded protein response in the developing mouse brain

Keywords: AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; CGNs; cerebellar granule neurons; DAB; 3,3′-diaminobenzidine; DAPI; 4,6-diamidino-phenylindole; DCN; deep cerebellar nucleus; DG; dentate gyrus; DIV; days in vitro; EGL; external germinal laye

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Sensory systems: their impact on C. elegans survival

Keywords: DCVs; dense core vesicles; Deg/ENaC; degenerin/epithelial Na+ channel; ER; endoplasmic reticulum; ILPs; insulin-like peptides; NOMPC; no mechanoreceptor potential C; TRP; transient receptor potential; UPR; unfolded protein response; C. elegans; sensory sy

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2015 سفارش ترجمه

Candida albicans autophagy, no longer a bystander: Its role in tolerance to ER stress-related antifungal drugs

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; ATG; auophagy-related; MM-N; nitrogen source-depleted minimum medium; Cvt; cytosol-to-vacuole; TEM; transmission electron microscopy; PM; plasma membrane; cER; cytoplasmic ER; AP; autophagosome; E

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Disruption of the unfolded protein response (UPR) by lead compound selectively suppresses cancer cell growth

Keywords: Selective cancer therapy; Unfolded protein response; 2DG; UPR disrupter; UPR; unfolded protein response; 2DG; 2-deoxy-D-glucose; IRE1; inositol-requiring enzyme 1; XBP1; X-box binding protein 1; GRP78; glucose-regulated protein 78 kDa; TM; tunicamycin;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2015 سفارش ترجمه

Amyloidogenic lysozymes accumulate in the endoplasmic reticulum accompanied by the augmentation of ER stress signals

Keywords: Armet; arginine-rich, mutated in early stage tumors; ATF4; activating transcription factor 4, a PERK downstream target; ATF6α; activating transcription factor 6α; CHOP; C/EBP homologous protein; DAPI; diamidino-2-phenylindole; EDEM1; ER degradation-enha

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

On the role of 4-hydroxynonenal in health and disease

Keywords: AD; Alzheimer's disease; ALDH; aldehyde dehydrogenase; AMI; acute myocardial infarction; ARE; antioxidant response element; CDK; cyclin-dependent kinase; CHF; chronic heart failure; DHLA; dihydrolipoic acid; ER; endoplasmic reticulum; GSH; glutathione; HL

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2015 سفارش ترجمه

Cellular stress responses in hepatitis C virus infection: Mastering a two-edged sword

Keywords: Hepatitis C virus; UPR; Oxidative stress; Auto-mitophagy; SIGMAR1;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2015 سفارش ترجمه

CTP:phosphocholine cytidylyltransferase: Function, regulation, and structure of an amphitropic enzyme required for membrane biogenesis

Keywords: AI; auto-inhibitory; CCT; CTP:phosphocholine cytidylyltransferase; CCTsol; soluble form of CCT; CCTmem; membrane-bound form of CCT; CT; cytidylyltransferase; ECT; ethanolamine-phosphate cytidylyltransferase; ERK; extracellular signal-regulated kinase; GCT

دانلود رایگان متن کامل مقاله ISI 25 صفحه سال انتشار : 2015 سفارش ترجمه

Endoplasmic reticulum stress-mediated autophagy contributes to bluetongue virus infection via the PERK-eIF2α pathway

Keywords: Bluetongue virus (BTV); Autophagy; Endoplasmic reticulum (ER) stress; PERK-eIF2α pathway; Replication; ER; endoplasmic reticulum; UPR; unfolded protein response; PERK; RNA-dependent protein kinase (PKR)-like endoplasmic reticulum (ER) kinase; eIF2α; the

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2015 سفارش ترجمه

Zebrafish: An Important Tool for Liver Disease Research

Keywords: Development; Technology; Liver Cancer; Toxicology; Regeneration; ALD; alcoholic liver disease; CYP; cytochrome P450; DILI; drug-induced liver injury; DMBA; dimethylbenzanthracene; dpf; days postfertilization; ER; endoplasmic reticulum; FLD; fatty liver di

دانلود رایگان متن کامل مقاله ISI 47 صفحه سال انتشار : 2015 سفارش ترجمه

Selective multifaceted E3 ubiquitin ligases barricade extreme defense: Potential therapeutic targets for neurodegeneration and ageing

Keywords: AAD; active adenylation domain; 4-PBA; 4-phenylbutyric acid; 6-OHDA; 6-hydroxydopamine; ABCG5/8; ATP-binding cassette sub-family G member 5/8; AD; Alzheimer's disease; AIB1; amplified in breast cancer 1; AIP4; atrophin-1 interacting protein 4; AMPA; α-

دانلود رایگان متن کامل مقاله ISI 54 صفحه سال انتشار : 2015 سفارش ترجمه

Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation

Keywords: ATF6; activating transcription factor 6; CHOP; C/EBP homologous protein; eIF2α; the eukaryotic initiation factor 2α; ER; endoplasmic reticulum; IRE1; inositol-requiring enzyme 1; PERK; double-stranded RNA-activated protein kinase (PKR)-like ER kinase; s

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Dipeptidyl petidase-IV inhibitor (gemigliptin) inhibits tunicamycin-induced endoplasmic reticulum stress, apoptosis and inflammation in H9c2 cardiomyocytes

Keywords: ROS; reactive oxygen species; GLP-1; glucagon-like peptide-1; DPP-IV; dipeptidyl peptidase-IV; Erk; extracellular signal-regulated kinases; ER; endoplasmic reticulum; IL-6; interlukin-6; TNF-α; tumor necrosis factor-α; BNP; brain natriuretic peptide; SD

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Calcium channel blocker verapamil accelerates gambogic acid-induced cytotoxicity via enhancing proteasome inhibition and ROS generation

Keywords: GA; gambogic acid; Ver; verapamil; Ab; antibody; ER; endoplasmic reticulum; ROS; reactive oxygen species; z-VAD-FMK; carbobenzoxy-valyl-alanyl-aspartyl-(O-methyl)-fluoromethylketone; CT-like; chymotrypsin-like; DCFH-DA; 2′,7′-dichlorfluorescein-diacet

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2014 سفارش ترجمه

Modulation of cellular signaling pathways in P23H rhodopsin photoreceptors

Keywords: UPR; Calpains; Mitochondria; mTOR; Autophagy; Rapamycin;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Sustained IRE1 and ATF6 signaling is important for survival of melanoma cells undergoing ER stress

Keywords: ERK; Endoplasmic reticulum stress; UPR; Melanoma;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

A calpain-cleaved fragment of β-catenin promotes BCRABL1 + cell survival evoked by autophagy induction in response to imatinib

Keywords: ULK1; unc-51-like kinase; ATG; autophagy-related proteins; FIP200; focal adhesion interacting protein 200; PI3K; class III phosphoinositide 3-kinase; Vps; vacuolar protein sorting; LC3; microtubule-associated protein 1 light chain 3; PE; phosphatidylethan

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Estrogen reduces endoplasmic reticulum stress to protect against glucotoxicity induced-pancreatic β-cell death

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; GRP-78; glucose-regulated protein 78; CHOP; CCAAT/enhancer-binding protein homologous protein; PI; propidium iodide; MTT; 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide thiazolyl bl

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2014 سفارش ترجمه

Role of the ubiquitin-proteasome system in cardiac dysfunction of adipose triglyceride lipase-deficient mice

Keywords: ATF6; activating transcription factor 6; ATGL; adipose triglyceride lipase; AKO; adipose triglyceride lipase knockout; AMC; amino-4-methylcoumarin; CHOP; C/EBP homologous protein; EDTA; ethylenediaminetetraacetic acid; ER; endoplasmic reticulum; FA; fatty

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

LKB1 inactivation sensitizes non-small cell lung cancer to pharmacological aggravation of ER stress

Keywords: LKB1; Lung cancer; Treatment; UPR; ER stress;

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Stromal cell derived factor-2 (Sdf2): A novel protein expressed in mouse

Keywords: Sdf2; mouse stromal cell derived factor 2; SDF2; human stromal cell derived factor 2; Sdf2l1; mouse stromal cell derived factor 2 like 1; SDF2L1; human stromal cell derived factor 2 like 1; SDF2-like; Arabidopsis thaliana stromal cell derived factor 2; Sd

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Acrolein activates cell survival and apoptotic death responses involving the endoplasmic reticulum in A549 lung cells

Keywords: AFC; amino trifluorocoumarin; AKT; protein kinase B; AMC; amino methylcoumarin; ARE; antioxidant response element; ATF6; activating transcription factor-6; BAPTA-AM; 1,2-Bis(2-aminophenoxy)ethane-N,N,N,N-tetraacetic acid tetrakis (acetoxymethyl ester); Ba

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2014 سفارش ترجمه

Inhibition of CYP4A Reduces Hepatic Endoplasmic Reticulum Stress and Features of Diabetes in Mice

Keywords: Mouse Model; Obesity; UPR; Proteomic AnalysisATF6, activating transcription factor 6; Bax, Bcl-2–associated X protein; Bcl-2, B-cell lymphoma-2; BI1, Bax inhibitor 1; BiP, immunoglobulin heavy-chain-binding protein; CHOP, C/EBP-homologous protein; CYP, cy

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Progranulin is required for proper ER stress response and inhibits ER stress-mediated apoptosis through TNFR2

Keywords: PGRN; Endoplasmic reticulum stress; Apoptosis; UPR; TNF receptor;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Neuroinflammation and endoplasmic reticulum stress are coregulated by cyclo(His-Pro) to prevent LPS neurotoxicity

Keywords: AD; Alzheimer's disease; AIDS; acquired immune deficiency syndrome; ALS; amyotrophic lateral sclerosis; Ara C; (β-d-Arabinofuranosyl)cytosin; Bip; binding immunoglobulin protein/78 kDa glucose-regulated protein; CCM; cell conditioned medium; CHOP; C/EBP

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Mitogen-activated protein kinases and protein phosphatase 5 mediate glucocorticoid-induced cytotoxicity in pancreatic islets and β-cells

Keywords: ASK-1; apoptosis signal-regulating kinase 1; dexa; dexamethasone; eIF2α; eukaryotic translation initiation factor 2α; GC; glucocorticoid; GR; glucocorticoid receptor; JNK; c-Jun N-terminal kinase; MAPK; mitogen-activated protein kinase; PP5; serine/thre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Keywords: Peroxisomes; Cholesterol; Isoprenoid; Pex2; SREBP-2; ER stress; Integrated stress response; Unfolded protein response; Zellweger syndrome; ACAT; acetoacetyl-CoA thiolase; ATF; activating transcription factor; BA; bile acid; CHOP; C/EBP homologous protein;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Mitochondrial chaperone TRAP1 activates the mitochondrial UPR and extends healthspan in Drosophila

Keywords: TRAP1; Ageing; Healthspan; Mitochondria; UPR; Drosophila;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Isolation and characterization of MdATG18a, a WD40-repeat AuTophaGy-related gene responsive to leaf senescence and abiotic stress in Malus

Keywords: ATG18; AuTophaGy-related gene 18; CRL4; cullin4-RING ubiquitin ligase complex; Cvt; cytoplasm-to-vacuole targeting; DWD; DNA-binding WD40 proteins; EF-1α; elongation factor 1 alpha gene; ER; endoplasmic reticulum; MV; methyl viologen; ORF; open reading f

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Metabolic and transcriptional responses of gilthead sea bream (Sparus aurata L.) to environmental stress: New insights in fish mitochondrial phenotyping

Keywords: ACAA2; 3-ketoacyl-CoA thiolase, mitochondrial; AIFM1; apoptosis-related protein 1; AIFM3; apoptosis-related protein 3; ANOVA; analysis of variance; BAX; apoptosis regulator BAX; BCL2; apoptosis regulator Bcl-2; BCLX; Bcl-2-like protein 1; CAT; catalase; C

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Silencing glucose-regulated protein 78 induced renal cell carcinoma cell line G1 cell-cycle arrest and resistance to conventional chemotherapy

Keywords: Grp78; Herp; VHL; UPR; Cell cycle; Chemotherapy;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Histone H3K4 methyltransferase Mll1 regulates protein glycosylation and tunicamycin-induced apoptosis through transcriptional regulation

Keywords: H6pd; hexose-6-phosphate dehydrogenase; Galnt12; UDP-N-acetyl-alpha-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase 12; Ugp2; UDP-glucose pyrophosphorylase 2; IRE1; Inositol-Requiring Protein-1; ATF6; Activating Transcription Factor-6; PERK;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The E3 Ubiquitin Ligase gp78 Protects against ER Stress in Zebrafish Liver

Keywords: Zebrafish; gp78/AMFR; UPR; Lipogenesis; Cholesterol; ERAD

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Yessotoxin induces ER-stress followed by autophagic cell death in glioma cells mediated by mTOR and BNIP3

Keywords: YTX; yessotoxin; DE; differentially expressed; UPR; unfolded protein response; ER-stress; endoplasmic reticulum stress; mTOR; mechanistic target of rapamycin (serine/threonine kinase); LC3; microtubule-associated protein 1 light chain 3 alpha; BNIP3; BCL2

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Oxidative stress induces mitochondrial dysfunction and a protective unfolded protein response in RPE cells

Keywords: AMD; age-related macular degeneration; ATF4; activating transcription factor 4; ATF6; activating transcription factor 6; CHOP; CCAAT/enhancer-binding protein-homologous protein; C/EBP-β; CCAAT/enhancer binding protein β; CSE; cigarette smoke extract; IR

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Chemical chaperones reduce ionizing radiation-induced endoplasmic reticulum stress and cell death in IEC-6 cells

Keywords: ER; endoplasmic reticulum; UPR; unfolded protein response; eIF2α; eukaryotic translation initiation factor 2α; ATF4; activating transcription factor 4; PERK; RNA-dependent-protein-kinase-like ER kinase; PBA; 4-phenylbutyric acid; siRNA; small interferin

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2014 سفارش ترجمه

Expression of neuropeptide Y and agouti-related protein mRNA stimulated by glucocorticoids is attenuated via NF-κB p65 under ER stress in mouse hypothalamic cultures

Keywords: ER; endoplasmic reticulum; NPY; neuropeptide Y; AgRP; agouti-related protein; UPR; unfolded protein response; TG; thapsigargin; TN; tunicamycin; DEX; dexamethasone; GR; glucocorticoid receptor; p38 MAPK; p38 mitogen-activated protein kinases; Agouti-relat

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Calumenin has a role in the alleviation of ER stress in neonatal rat cardiomyocytes

Keywords: ATF; activating transcription factor; Ad-calu; adenovirus containing mouse calumenin 1 cDNA; Ad-lacZ; adenovirus containing lacZ gene; CHOP; C/EBP-homologous protein; ERAD; ER-associated degradation; eIF2; eukaryotic initiation factor 2; ERp57; the thiol

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The autophagy associated gene, ULK1, promotes tolerance to chronic and acute hypoxia

Keywords: ULK1; Autophagy; UPR; Hypoxia;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

Mitochondria and ALS: Implications from novel genes and pathways

Keywords: ALS; Amyotrophic Lateral Sclerosis; CFP; Cyan Fluorescent Protein; ER; Endoplasmic Reticulum; FUS/TLS; Fused in Sarcoma/Translocated in Liposarcoma; GSH; Glutathione; HAT; Histone Acetyl Transferase; HDAC; Histone Deacetylase; ROS; Reactive Oxygen Species

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The PERK/ATF4/LAMP3-arm of the unfolded protein response affects radioresistance by interfering with the DNA damage response

Keywords: Breast cancer; Radiation; Resistance; UPR; LAMP3;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

New small molecule inhibitors of UPR activation demonstrate that PERK, but not IRE1α signaling is essential for promoting adaptation and survival to hypoxia

Keywords: UPR; Hypoxia; Small-molecule inhibitors; PERK; IRE1α;

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Understanding the molecular mechanism(s) of hepatitis C virus (HCV) induced interferon resistance

Keywords: HCV; hepatitis C virus; UTR; untranslated regions; IFN; interferon; ISG; interferon stimulatory genes; IRES; internal ribosome entry site; IFNAR; IFN-α receptor; STAT; signal transducer and activator of transcription; TLR3; toll like receptor 3; DsRNA; d

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2013 سفارش ترجمه

Chibby drives β catenin cytoplasmic accumulation leading to activation of the unfolded protein response in BCR-ABL1 + cells

Keywords: CML; chronic myeloid leukemia; TK; tyrosine kinase; LSC; leukemic stem cell; APC; Adenomatous polyposis coli; GSK3; glycogen synthase kinase 3; CBY; Chibby; TCF; T cell factor; LEF; lymphoid enhancer factor; ER; endoplasmic reticulum; UPR; unfolded protei

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه

Involvement of ASK1-p38 pathway in the pathogenesis of diabetes triggered by pancreatic ß cell exhaustion

Keywords: Ins2; Insulin 2 protein; ER; endoplasmic reticulum; ASK1; apoptosis signal-regulating kinase 1; UPR; unfolded protein response; PERK; protein kinase RNA-like ER kinase; ATF6; activating transcription factor 6; IRE1; inositol-requiring enzyme 1; ERAD; ER-a

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2013 سفارش ترجمه