دانلود مقالات ISI درباره Upr + ترجمه فارسی

4-Phenylbutyric acid reduces mutant-TGFBIp levels and ER stress through activation of ERAD pathway in corneal fibroblasts of granular corneal dystrophy type 2

Keywords: ER stress; UPR; ERAD; 4-Phenylbutyric acid; TGFBIp; GCD2; Corneal fibroblasts; 4-PBA; Sodium 4-phenylbutyric acid; ATF6; Activating transcription factor 6; BiP; Binding immunoglobulin protein; CHOP; C/EBP homologous protein; ER; Endoplasmic reticulum; ERA

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

PEK-1 is crucial for hormesis induced by inhibition of the IRE-1/XBP-1 pathway in the Caenorhabditis elegans mev-1 mutant

Keywords: Proteostasis; Unfolded protein response; Proteasome; Hormesis; Caenorhabditis elegans; ABU; activated in blocked unfolded protein response; ANOVA; analysis of variance; ATF-6; activating transcription factor 6; BiP; immunoglobulin binding protein; C. ele

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2016 سفارش ترجمه

High-level expression of Proteinase K from Tritirachium album Limber in Pichia pastoris using multi-copy expression strains

Keywords: Proteinase K; Pichia pastoris; Multi-copy expression; qPCR; quantitative polymerase chain reaction; SDS; sodium dodecyl sulfate; BMGY; buffered glycerol-complex medium; BMMY; buffered methanol-complex medium; MD; minimal dextrose medium; SDS-PAGE; sodium

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Resveratrol triggers ER stress-mediated apoptosis by disrupting N-linked glycosylation of proteins in ovarian cancer cells

Keywords: RSV; resveratrol; NLG; protein N-linked glycosylation; UPR; unfolded protein responses; ER; endoplasmic reticulum; G.F; glucose free media; TM; tunicamycin; PBMC; peripheral blood mononuclear cells; RBC; red blood cells; PERK; protein kinase RNA-like ER k

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

Lipid homeostasis is involved in plasma membrane and endoplasmic reticulum stress in Pichia pastoris

Keywords: Lipid saturation; Spt23; Plasma membrane; Unfolded protein response; Reactive oxygen species; Endoplasmic reticulum; DCFH-DA; 2′, 7′-dichlorodihydro-fluorescein diacetate; ER; endoplasmic reticulum; LDs; lipid droplets; OA; oleic acid; ROS; reactive o

دانلود رایگان متن کامل مقاله ISI 7 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewER chaperones in neurodegenerative disease: Folding and beyond

Keywords: ER chaperones; UPR; ER stress; Protein aggregation; Neurodegenerative disease;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

A novel role of c-FLIP protein in regulation of ER stress response

Keywords: Mouse embryonic fibroblast; Endoplasmic reticulum stress; UPR; Apoptosis; c-FLIP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-fetoprotein is a biomarker of unfolded protein response and altered proteostasis in hepatocellular carcinoma cells exposed to sorafenib

Keywords: AFP; alpha-feto protein; AREG; amphiregulin; ATF6; activating transcription factor-6; DFX; deferoxamine; eIF-2α; eukaryotic translation initiation factor-2α; ERK1/2; extracellular signal-regulated kinase 1/2; IRE-1α; inositol-requiring enzyme-1α; GRP;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

The intersection between growth factors, autophagy and ER stress: A new target to treat neurodegenerative diseases?

Keywords: Autophagy; UPR; IGFs; ER stress, aggregation, neurodegenerative disease

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Deletion of Atf6α enhances kainate-induced neuronal death in mice

Keywords: ATF6α; Kainate; Neuronal death; UPR; Ca2+ATF6α, activating transcription factor 6α; CNS, central nervous system; CHOP, C/EBP homologous protein; DAPI, 4′,6-diamidino-2-phenylindole; ER, endoplasmic reticulum; FJC, Fluoro-Jade C; GFAP, glial fibrillary aci

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2016 سفارش ترجمه

Anti-inflammatory actions of (−)-epicatechin in the adipose tissue of obese mice

Keywords: ATF6; activating transcription factor 6; EC; (−)-epicatechin; ER; endoplasmic reticulum; Ero1; FAD-dependent enzyme ER oxireductin-1 (Ero1); HFD; high fat diet; 4-HNE; 4-hydroxynonenal; IκB; inhibitor of nuclear factor κB; IKK; IκB kinase; IL-6; inte

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2016 سفارش ترجمه

Signaling the Unfolded Protein Response in primary brain cancers

Keywords: Unfolded Protein Response; Glioma; UPR; Brain cancer; Stress; Endoplasmic reticulum

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Research paperPhosphatidylcholine as a metabolic cue for determining B cell fate and function

Keywords: CCTα; Antibody-secreting cell; Antibody; Germinal centers; T cell-dependent antigen; Unfolded protein response; Phospholipid biosynthesis; ASC; antibody-secreting cell; ER; endoplasmic reticulum; UPR; unfolded protein response; XBP1; X-box binding protei

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewReprint of: Signaling the Unfolded Protein Response in primary brain cancers

Keywords: Unfolded Protein Response; Glioma; UPR; Brain cancer; Stress; Endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2016 سفارش ترجمه

Astemizole-Histamine induces Beclin-1-independent autophagy by targeting p53-dependent crosstalk between autophagy and apoptosis

Keywords: AST; Astemizole; HIS; Histamine; H1R; Histamine H1 receptor; ROS; Reactive oxygen species; ER; Endoplasmic reticulum; PERK; Protein kinase R-like endoplasmic reticulum kinase; IRE1α; Inositol-requiring enzyme 1; ATF; Activating transcription factor; JNK;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Endoplasmic reticulum-derived reactive oxygen species (ROS) is involved in toxicity of cell wall stress to Candida albicans

Keywords: ROS; reactive oxygen species; OSR; oxidative stress response; MMP; mitochondrial membrane potential; VMP; vacuolar membrane permeabilization; C-DCFDA; 5-(6)-carboxy-2′,7′-dichlorofluorescein diacetate; DCFH-DA; 2′,7′-dichlorofluorescin diacetate;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitic acid aggravates inflammation of pancreatic acinar cells by enhancing unfolded protein response induced CCAAT-enhancer-binding protein β-CCAAT-enhancer-binding protein α activation

Keywords: AP; acute pancreatitis; ATF6; activating transcription factor 6; BSA; bovine serum albumin; CCK-8; cholecystokinin-8; C/EBP; CCAAT-enhancer-binding protein; CHOP; CCAAT/enhancer binding protein (C/EBP) homologous protein; eIF2; αeukaryotic translation in

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2016 سفارش ترجمه

Quercetin attenuates tau hyperphosphorylation and improves cognitive disorder via suppression of ER stress in a manner dependent on AMPK pathway

Keywords: AMPK; ER stress; NLRP3 inflammasome; Quercetin; Quercetin-3-O-glucuronide; Tau phosphorylation; Compound C (PubChem CID: 11524144); Metformin (PubChem CID: 14219); Okadaic acid (PubChem CID: 446512); Quercetin (PubChem CID: 5280343); Quercetin-3-O-glucuro

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Intracellular Ca2+ signaling and Ca2+ microdomains in the control of cell survival, apoptosis and autophagy

Keywords: Apoptosis; Autophagy; Endoplasmic reticulum; IP3 receptor; Lysosomes; Mitochondria; AMBRA1; autophagy/Beclin 1 regulator 1; AMPK; AMP-activated kinase; ATF4; activating transcription factor-4; Atg; autophagy-related; BIRD-2; Bcl-2/IP3R disruptor-2; CREB;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Pro-inflammatory cytokines enhance ERAD and ATF6α pathway activity in salivary glands of Sjögren's syndrome patients

Keywords: Sjögren's syndrome; Salivary glands; Endoplasmic reticulum stress; UPR; ERAD; Cytokines;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

Palmitoylethanolamide protects mice against 6-OHDA-induced neurotoxicity and endoplasmic reticulum stress: In vivo and in vitro evidence

Keywords: PEA; palmitoylethanolamide; PPAR; peroxisome proliferator activated receptor; PD; Parkinson's disease; DA; dopamine; ER; endoplasmic reticulum; UPR; unfolded protein response; eIF-2α; elongation initiation factor-2α; 6-OHDA; 6-hydroxydopamine; MPTP; 1

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2016 سفارش ترجمه

ReviewThe entangled ER-mitochondrial axis as a potential therapeutic strategy in neurodegeneration: A tangled duo unchained

Keywords: Mitochondria; ER; Calcium; Neurodegeneration; Mitochondrial dynamics; Mitochondrial transport; UPR;

دانلود رایگان متن کامل مقاله ISI 17 صفحه سال انتشار : 2016 سفارش ترجمه

Single Amino Acid Deletion in Kindlin-1 Results in Partial Protein Degradation Which Can Be Rescued by Chaperone Treatment

Keywords: FA; focal adhesion; FERM; 4.1 protein, ezrin, radixin, moesin; F0-F3; FERM subdomains; FERMT1; kindlin-1 gene; KS; Kindler syndrome; K1; wild-type kindlin-1; K1R100del; mutant kindlin-1 p.R100del; KSKR100del; KS keratinocytes of patient 1 bearing the ho

دانلود رایگان متن کامل مقاله ISI 22 صفحه سال انتشار : 2016 سفارش ترجمه

Role of miR-181a-5p and endoplasmic reticulum stress in the regulation of myogenic differentiation

Keywords: ATF6; activating transcription factor 6; BMP4; bone morphogenetic protein 4; DM; differentiation medium; ER; endoplasmic reticulum; GM; growth medium; GRP78/BIP; glucose-regulated protein of 78 kDa/binding protein for immunoglobulins; IGF-1; insulin-like

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Suppression of StarD7 promotes endoplasmic reticulum stress and induces ROS production

Keywords: BSA; bovine serum albumin; CHX; cycloheximide; DMSO; dimethyl sulfoxide; ER; endoplasmic reticulum; eIF2α; eukaryotic translation initiation factor 2, subunit 1α; GRP78/BiP; glucose regulated protein 78/immunoglobulin heavy chain-binding protein; H2DCFD

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2016 سفارش ترجمه

Netrin-1 Protects Hepatocytes Against Cell Death Through Sustained Translation During the Unfolded Protein Response

Keywords: Netrin; UPR; Hepatocyte; Translation; ATF6; activated transcription factor 6; CMV; cytomegalovirus; DAPK; death-associated protein kinase; DMS; dimethyl sulfate; DR; dependence receptor; DTT; dithiothreitol; eIF2α; Eukaryotic translation initiation facto

دانلود رایگان متن کامل مقاله ISI 30 صفحه سال انتشار : 2016 سفارش ترجمه

Adsorption kinetics studies of an anti-inflammatory drug Mesalamine using Unsaturated Polyester Resin (UPR)

Keywords: Adsorption mechanism; Diffusion kinetics; Thermodynamics; Mesalamine; UPR;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2016 سفارش ترجمه

Knockdown of triglyceride synthesis does not enhance palmitate lipotoxicity or prevent oleate-mediated rescue in rat hepatocytes

Keywords: ATF3; activating transcription factor 3; CHOP; CCAAT/enhancer-binding protein homologous protein; DGAT; diacylglycerol acyltransferase; ER; endoplasmic reticulum; FFA; free fatty acid; MUFA; monounsaturated fatty acid; NAFLD; non-alcoholic fatty liver dis

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Terpene glycoside component from Moutan Cortex ameliorates diabetic nephropathy by regulating endoplasmic reticulum stress-related inflammatory responses

Keywords: TCM; traditional Chinese Medicine; MC; Moutan Cortex; TG; terpene glycoside; DN; diabetic nephropathy; STZ; streptozotocin; AGEs; advanced glycation end-products; ER; endoplasmic reticulum; 4-PBA; 4-phenylbutyric acid; AG; amino guanidine; TEM; transmissi

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Novel variants of SERPIN1A gene: Interplay between alpha1-antitrypsin deficiency and chronic obstructive pulmonary disease

Keywords: COPD; chronic obstructive pulmonary disease; SERPIN1A; serine protease inhibitor 1A; AAT; alpha1-antitrypsin; UPR; unfolded protein response;

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Alpha-lipoic acid attenuates endoplasmic reticulum stress-induced insulin resistance by improving mitochondrial function in HepG2 cells

Keywords: ALA; alpha-lipoic acid; ER stress; endoplasmic reticulum (ER) stress; HepG2; hepatoblastoma cell line; Tun; tunicamycin; OXPHOS; oxidative phosphorylation; Olig; oligomycin; T2DM; type 2 diabetes mellitus; IRS; insulin receptor substrate; PI3K; phosphatid

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

Expression of DRD2 Is Increased in Human Pancreatic Ductal Adenocarcinoma and Inhibitors Slow Tumor Growth in Mice

Keywords: TMA; Unfolded Protein Response; Drug Repositioning; Pancreas; cAMP; cyclic adenosine monophosphate; CP; chronic pancreatitis; CSC; cancer stem cells; DMSO; dimethylsulfoxide; DRD2; dopamine receptor D2; ER; endoplasmic reticulum; FDA; Food and Drug Admini

دانلود رایگان متن کامل مقاله ISI 36 صفحه سال انتشار : 2016 سفارش ترجمه

αB-crystallin: Portrait of a malignant chaperone as a cancer therapeutic target

Keywords: Molecular chaperone; Stress response; Apoptosis; Cancer; Metastasis; Drug target; CRYAB; αB-crystallin gene; EMT; epithelial-to-mesenchymal transition; ER; endoplasmic reticulum; sHsp; small heat shock protein; HBMECs; human brain microvascular endotheli

دانلود رایگان متن کامل مقاله ISI 39 صفحه سال انتشار : 2016 سفارش ترجمه

Autophagy in the eye: Development, degeneration, and aging

Keywords: Autophagy; Retina; Chaperone mediated autophagy; Lysosomes; Mitophagy; Retinal ganglion cells; Retinal pigment epithelial cells; Photoreceptor; Glaucoma; Macular degeneration; Retinal dystrophies; Diabetic retinopathy; 3-MA; 3-methyl adenine; 8-OH DPAT; 8

دانلود رایگان متن کامل مقاله ISI 40 صفحه سال انتشار : 2016 سفارش ترجمه

Gu-Ben-Fang-Xiao decoction attenuates sustained airway inflammation by suppressing ER stress response in a murine asthma remission model of respiratory syncytial virus infection

Keywords: GBFXD; GuBenFangXiao decoction; RSV; respiratory syncytial virus; OVA; ovalbumin; ER; endoplasmic reticulum; UPR; unfolded protein response; TCM; traditional Chinese medicine; Mont; montelukast sodium; DEX; dexamethasone; HPLC; high performance liquid chr

دانلود رایگان متن کامل مقاله ISI 42 صفحه سال انتشار : 2016 سفارش ترجمه

Beyond PM2.5: The role of ultrafine particles on adverse health effects of air pollution

Keywords: PM2.5; Ultrafine particles; PM0.1; Toxicology; Air pollution; Nanotoxicology; ADME; absorption distribution metabolism and excretion; ARE; antioxidant response; AOP; adverse outcome pathways; CFD; computational fluid dynamics; CMD; count median diameter;

دانلود رایگان متن کامل مقاله ISI 43 صفحه سال انتشار : 2016 سفارش ترجمه

Structural and molecular bases of rod photoreceptor morphogenesis and disease

Keywords: Photoreceptor; Cryo-electron tomography; Retinal imaging; Retinal degeneration; Disease mechanisms; Ciliopathies; ADRP; autosomal dominant retinitis pigmentosa; BBS; Bardet-Biedl syndrome; BBSome; membrane coat complex formed by BBS gene products; Cryo-ET

دانلود رایگان متن کامل مقاله ISI 44 صفحه سال انتشار : 2016 سفارش ترجمه

Molecular and cellular mechanisms linking inflammation to insulin resistance and β-cell dysfunction

Keywords: AMPK; AMP-activated protein kinase; ATM; adipose tissue macrophages; CCL; chemokine (C-C motif) ligand; CCR2; chemokine (C-C motif) receptor 2; CX3CL1; chemokine (C-X3-C motif) ligand 1; CX3CR1; chemokine (C-X3-C motif) receptor; CXCL; CXC chemokine ligan

دانلود رایگان متن کامل مقاله ISI 69 صفحه سال انتشار : 2016 سفارش ترجمه

Genomics of human fatty liver disease reveal mechanistically linked lipid droplet-associated gene regulations in bland steatosis and nonalcoholic steatohepatitis

Keywords: ACACB; acetyl-CoA carboxylase beta acetyl-CoA carboxylase beta; ACAT1; acetyl-CoA acetyltransferase 1; ACLY; ATP citrate lyase; AMPK; 5′AMP-activated protein kinase; ASCL1; acyl-CoA synthetase long-chain family member 1; ACSL4; acyl CoA synthetases long

دانلود رایگان متن کامل مقاله ISI 80 صفحه سال انتشار : 2016 سفارش ترجمه

Phenazine derivatives cause proteotoxicity and stress in C. elegans

Keywords: PD; Parkinson's disease; HD; Huntington's disease; PCA; phenazine-1-carboxylic acid; PCN; pyocyanin; 1-HP; 1-hydroxyphenazine; NAC; N-acetyl cysteine; UPS; ubiquitin proteasome system; UPR; unfolded protein response; Phenazines; C. elegans; ER stress; α-

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2015 سفارش ترجمه

An SOD1 deficiency enhances lipid droplet accumulation in the fasted mouse liver by aborting lipophagy

Keywords: Fasting; Lipophagy; Liver steatosis; Oxidative stress; Superoxide dismutase; ACC; acetyl CoA-carboxylase; ALT; alanine aminotransferase; apoB; apolipoprotein B; BSA; bovine serum albumin; ER; endoplasmic reticulum; FAS; fatty acid synthase; GLU; glucose;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Distribution of Sec24 isoforms to each ER exit site is dynamically regulated in Saccharomyces cerevisiae

Keywords: ER exit site; COPII; Sec24; Lst1; UPR; Endoplasmic reticulum;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

GABARAPL1 is required for increased EGFR membrane expression during hypoxia

Keywords: EGFR; GABARAPL1; Autophagy; Hypoxia; UPR; Receptor trafficking;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

ER stress and hexosamine pathway during tumourigenesis: A pas de deux?

Keywords: UPR; Nutrient shortage; Metabolism; HBP

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2015 سفارش ترجمه

Tauroursodeoxycholic acid prevents stress induced aggregation of proteins in vitro and promotes PERK activation in HepG2 cells

Keywords: TUDCA; PERK; UPR; BSA; Protein aggregation; LC–MS/MS; COX1; EcoR1

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

Keywords: ER stress; UPR; ubiquitin; hypoxia; autophagy; mitochondria

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

ER proteostasis addiction in cancer biology: Novel concepts

Keywords: Cancer; ER stress; Proteostasis; UPR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Altered expression of microRNAs in the response to ER stress

Keywords: microRNA; Noncoding RNA; ER stress; UPR;

دانلود رایگان متن کامل مقاله ISI 8 صفحه سال انتشار : 2015 سفارش ترجمه

Research ArticleRole for the endoplasmic reticulum stress sensor IRE1α in liver regenerative responses

Keywords: IRE1α; inositol-requiring enzyme 1α; ER; endoplasmic reticulum; CCl4; carbon tetrachloride; PH; partial hepatectomy; UPR; unfolded protein response; LKO; liver specific IRE1α knockout; IL-6; interleukin 6; STAT3; signal transducer and activator of tran

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه

Molecular characterization of two novel molecular chaperones in bacterial-challenged Apostichopus japonicus

Keywords: GRP78; 78 kDa glucose-regulated protein; PDI; Protein disulfide isomerase; ER; Endoplasmic reticulum; ORF; Open reading frame; HSP70; Heat shock protein 70; UTR; Untranslated region; UPR; Unfolded protein response; HSPs; Heat shock proteins; ROS; Reactiv

دانلود رایگان متن کامل مقاله ISI 9 صفحه سال انتشار : 2015 سفارش ترجمه