The effects of Liuwei Dihuang on canonical Wnt/β-catenin signaling pathway in osteoporosis
Keywords: Liuwei Dihuang; Wnt; β-catenin; Osteoporosis; Ovariectomized rat; Osteoblast
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The β-catenin E3 ubiquitin ligase SIAH-1 is regulated by CSN5/JAB1 in CRC cells
Keywords: AP-1; activator protein-1; APC; adenomatous polyposis coli; CK1; casein kinase 1; CoIP; co-immunoprecipitation; CRC; colorectal cancer; CRL; cullin RING E3 ubiquitin ligase; CSN; COP9 signalosome; CSN5; fifth subunit of the CSN; Cul1; cullin-1; GSK-3β; g
Syndecan-4 inhibits Wnt/β-catenin signaling through regulation of low-density-lipoprotein receptor-related protein (LRP6) and R-spondin 3
Keywords: Wnt; Syndecan-4; LRP6; Fibronectin; R-spondin;
Inadequate mito-biogenesis in primary dermal fibroblasts from old humans is associated with impairment of PGC1A-independent stimulation
Keywords: 12S; mitochondrial rRNA; AICAR; aminoimidazole-4-carboxamide riboside, an adenosine analogue stimulating AMPK; AMPK; catalytic α1/2-subunit of AMP dependent protein kinase; pAMPK; AMPK phosphorylated at serine 172 of the α-subunit; AU; arbitrary units;
A ciliopathy with hydrocephalus, isolated craniosynostosis, hypertelorism, and clefting caused by deletion of Kif3a
Keywords: Intraflagellar transport protein; Cranial neural crest; Craniofacial; Syndrome; Midline; Wnt; Hedgehog;
Use of small molecule inhibitors of the Wnt and Notch signaling pathways during Xenopus development
Keywords: Wnt; Notch; IWR-1; XAV939; WntC59; BIO; DAPT; RO4929097; Axin2; Hematopoeisis;
Modulation of stemness in a human normal intestinal epithelial crypt cell line by activation of the WNT signaling pathway
Keywords: BMP; bone morphogenetic protein; BMPR; BMP receptor; BrdU; bromodeoxyuridine; CBC; crypt-base columnar; GSK3β; glycogen synthase kinase 3β; HIEC; human intestinal epithelial crypt; LGR5; leucine-rich-repeat-containing G-protein-coupled receptor-5; OLFM4
Wnt/β-catenin signaling regulates follicular development by modulating the expression of Foxo3a signaling components
Keywords: APC; adenomatosis polyposis coli; CTNNB1; β-catenin; DMSO; dimethylsulfoxide; CYP11A1; P450 cholesterol side chain cleavage; CYP19A1; cytochrome P450 aromatase; FBS; fetal bovine serum; Foxo; Forkhead box O; FZD; frizzled; GSK3β; glycogen synthase kinas
Analysis of gene expression changes in A549 cells induced by organic compounds from respirable air particles
Keywords: A549; human adenocarcinoma alveolar basal epithelial cells type II; AhR; aryl hydrocarbon receptor; B[a]P; benzo[a]pyrene; BMP; bone morphogenetic proteins; cDNA; complementary DNA; c-PAH; carcinogenic polycyclic aromatic hydrocarbon; cRNA; complementary
WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies
Keywords: WWOX; FRA16D; TGFβ; WNT; Lipid metabolism; Epilepsy;
Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants
Keywords: Retromer; Wnt; Wntless; Membrane trafficking; Caenorhabditis elegans;
Synergistic effect of Wnt modulatory small molecules and an osteoinductive ceramic on C2C12 cell osteogenic differentiation
Keywords: ALP; alkaline phosphatase; hMSC; human mesenchymal stem cell; TCP; tricalcium phosphate; THQ; tetrahydroquinoline; PP; pyrazolopyrimidine; Ph; phenyl; C2C12; Mesenchymal stromal cells; Tricalcium phosphate ceramic; Small molecules; Wnt; Osteogenesis;
Ca2+ handling and sensitivity in airway smooth muscle: Emerging concepts for mechanistic understanding and therapeutic targeting
Keywords: Asthma; Airway smooth muscle; Calcium; Sensitisation; WNT; Contraction;
Sfrp1a and Sfrp5 function as positive regulators of Wnt and BMP signaling during early retinal development
Keywords: Retina; Wnt; BMP; Sfrp1; Sfrp5; Coloboma; Gdf6;
ReviewColon carcinogenesis: Influence of Western diet-induced obesity and targeting stem cells using dietary bioactive compounds
Keywords: Colon cancer; Western diet; IGF-1; Insulin; Stem cells; Wnt; LGR5, ALDH1B1; Resveratrol; Curcumin; Lycopene; Grape seed extract;
The evolutionary history of vertebrate cranial placodes II. Evolution of ectodermal patterning
Keywords: Placodes; Six1; Eya; BMP; Wnt; Preplacodal ectoderm; Neural crest; Amphioxus; Ciona; Neural induction;
Is Alzheimer's disease related to metabolic syndrome? A Wnt signaling conundrum
Keywords: AMPK; AMP-activated protein kinase; STAT; activator of transcription; AGE; advanced glycation end products; AD; Alzheimer's disease; APP; amyloid precursor protein; Aβ; amyloid-β peptide; ACE; angiotensin converting enzyme; Ang I; angiotensin I; AR-II;
Short communicationAntibodies against Wnt receptor of muscle-specific tyrosine kinase in myasthenia gravis
Keywords: Myasthenia gravis; Neuromuscular junction; Acetylcholine receptor; Muscle-specific tyrosine kinase; Wnt;
Developmental consequences of the ColQ/MuSK interactions
Keywords: Acetylcholinesterase; Neuromuscular junction; Myasthenia; LRP4; Agrin; Wnt;
Sclerostin deficient mice rapidly heal bone defects by activating β-catenin and increasing intramembranous ossification
Keywords: Sclerostin; β-Catenin; Wnt; Fracture healing; Osteoblast; Intramembranous ossification;
Synthesis of novel inhibitors blocking Wnt signaling downstream of β-Catenin
Keywords: Wnt; Tcf; Haloquinone; Small inhibiting molecule;
Autocrine stimulation of osteoblast activity by Wnt5a in response to TNF-α in human mesenchymal stem cells
Keywords: Osteoblast; Alkaline phosphatase; Mineralization; Inflammation; TNF-α; Wnt; Ankylosing spondylitis;
Expression profile and function of Wnt signaling mechanisms in malignant mesothelioma cells
Keywords: Mesothelioma; Wnt; Gene expression; Proliferation;
Rats treated with AZD2858, a GSK3 inhibitor, heal fractures rapidly without endochondral bone formation
Keywords: Fracture healing; Wnt; Bone strength; Bone regeneration; Glycogen synthase kinase (GSK);
The mechanisms of planar cell polarity, growth and the Hippo pathway: Some known unknowns
Keywords: Planar cell polarity; Growth; Gradients; Morphogens; Hippo; Fat; Dachsous; Wnt; Frizzled; Van Gogh; Starry night;
Expression of wnt and frizzled genes during early sea star development
Keywords: Wnt; Fz; Sea star; Echinoderm; Embryo;
Roles of Wnt8a during formation and patterning of the mouse inner ear
Keywords: Wnt; Fgf; Otic placode; Otic specification;
3-Methoxyapigenin modulates β-catenin stability and inhibits Wnt/β-catenin signaling in Jurkat leukemic cells
Keywords: Leukemia; Wnt; β-catenin; Glycogen synthase kinase-3β (GSK-3β); Anti-cancer;
Original Full Length ArticleIn vivo and in vitro effects of a novel anti-Dkk1 neutralizing antibody in multiple myeloma
Keywords: Dkk1; wnt; Multiple myeloma; Osteoclast; Osteoblast;
Wnt interaction and extracellular release of prominin-1/CD133 in human malignant melanoma cells
Keywords: Prominin-1; Melanoma; Wnt; Catenin; Vesicles;
High-concentration of BMP2 reduces cell proliferation and increases apoptosis via DKK1 and SOST in human primary periosteal cells
Keywords: High-concentration BMP2; Wnt; SOST; DKK1; Periosteum; Proliferation;
Spatiotemporal expression of Wnt signaling pathway components during bovine placental development
Keywords: Wnt; Trophoblasts; Bovine placenta;
Requirement for frzb and fzd7a in cranial neural crest convergence and extension mechanisms during zebrafish palate and jaw morphogenesis
Keywords: Convergence extension; wnt; frizzled; frzb; fzd7a; Wnt9a; Cranial neural crest; Craniofacial; Zebrafish;
Modulation of the Wnt/beta-catenin pathway in human oligodendroglioma cells by Sox17 regulates proliferation and differentiation
Keywords: HOG; human oligodendroglioma; ODGs; oligodendrogliomas; OPCs; oligodendrocyte progenitor cells; Shh; sonic hedgehog; SFRP1; secreted frizzled related protein; Sox17; SRY-Box containing gene 17; CNPase; 2â²,3â²-cyclic-nucleotide 3â²-phosphodiesterase; M
MicroRNA expression profiling of human bone marrow mesenchymal stem cells during osteogenic differentiation reveals Osterix regulation by miR-31
Keywords: 3â²UTR; 3â² untranslated region; ALP; Alkaline phosphatase; AP-1; Activator protein 1; ATF4; Activating transcription factor 4; BGLAP; Bone gamma-carboxyglutamate (gla) protein; BMP; Bone morphogenetic protein; COL1A1; Collagen, type I, alpha 1; FBS; Fe
Wnt signaling inhibits CTL memory programming
Keywords: T cells; Cytotoxicity; Wnt; GSK3; Cytokines; Memory; mTOR; Rapamycin;
Wnt signaling regulates left-right axis formation in the node of mouse embryos
Keywords: Left-right axis; Node; Mouse embryo; Wnt; Notch signaling;
Wnt/β-catenin signaling activates bone morphogenetic protein 2 expression in osteoblasts
Keywords: ALP; alkaline phosphatase; BGJ medium; Biggers, Gwatkin, and Judah medium; BMP; bone morphogenetic protein; β-TrCP; β-transducin repeat-containing protein; Col1a1; type I collagen 1a1; CTGF; connective-tissue growth factor; CREB; cAMP responsive element
What do mechanotransduction, Hippo, Wnt, and TGFβ have in common? YAP and TAZ as key orchestrating molecules in ocular health and disease
Keywords: biophysical cueing; mechanotransduction; YAP; TAZ; hippo; TGFβ; Wnt;
The Xenopus Tgfbi is required for embryogenesis through regulation of canonical Wnt signalling
Keywords: Tgfbi; Xenopus laevis; Wnt; Development;
Different thresholds of Wnt-Frizzled 7 signaling coordinate proliferation, morphogenesis and fate of endoderm progenitor cells
Keywords: Frizzled 7; Wnt; β-catenin; JNK; Endoderm; Foregut patterning; hhex; vent2; Xenopus;
C. elegans fmi-1/flamingo and Wnt pathway components interact genetically to control the anteroposterior neurite growth of the VD GABAergic neurons
Keywords: Flamingo; Axon guidance; Neurite growth; Anterior/posterior patterning; Wnt; Frizzled; Dishevelled;
Adenosine A1 receptor stimulation enhances osteogenic differentiation of human dental pulp-derived mesenchymal stem cells via WNT signaling
Keywords: ADA; adenosine deaminase; A1R; adenosine A1 receptors; A2AR; adenosine A2A receptors; A2BR; adenosine A2B receptors; A3R; adenosine A3 receptors; ALP; alkaline phosphatase; ARS; Alizarin Red S staining; CCPA; 2-chloro-N6-cyclopentyladenosine; CGS21680; 2-
Wntless is required for peripheral lung differentiation and pulmonary vascular development
Keywords: Wntless; Wnt; Lung development; Endothelium; Epithelium;
APC loss-induced intestinal tumorigenesis in Drosophila: Roles of Ras in Wnt signaling activation and tumor progression
Keywords: Adenomatous polyposis coli (APC); Wnt; Ras; Tumorigenesis; DE-cadherin; Drosophila;
Expression of sfrp1 and activation of the Wnt pathway in the adrenal glands of healthy ferrets and neutered ferrets with hyperadrenocorticism
Keywords: Ferret; Gonadectomy-induced adrenal gland tumours; sfrp1; Wnt
Regulation of Wnt/β-catenin signaling within and from osteocytes
Keywords: Wnt; Lrp5; Sclerostin; SOST; B-catenin; Osteocyte
The Wnt/beta-catenin signaling pathway establishes neuroanatomical asymmetries and their laterality
Keywords: Wnt; Habenula; Asymmetry; Laterality; Nodal; Zebrafish
Regulation of intestinal cancer stem cells
Keywords: Stem cells; Colon; Wnt; Notch; BMP; Differentiation; Hypoxia; Regulation; Myofibroblasts