13C-NMR-based metabolic fingerprinting of Citrus-type crude drugs

Five Citrus-type crude drugs (40 samples) were classified using 13C-NMR spectra-based metabolomics. The following eight metabolites were identified from the loading plots of multivariate analysis of the 13C-NMR spectra; naringin, neohesperidin, narirutin, synephrine, sucrose, α-glucose, β-glucose, and limonene. 13C-NMR spectra-based metabolic fingerprinting is a promising strategy for classifying crude drugs.