A prospective randomized pragmatic double-blinded comparison of 0.125% and 0.0625% bupivacaine for the management of pain after operation in patients undergoing major abdominal surgery

We were able to demonstrate that the incidence of hypotension was reduced with 0.0625% bupivacaine without affecting the quality of pain relief. However the overall incidence of hypotension remained high which restricted early mobilisation in some patients. Hypotension may be unavoidable when epidurals effectively control postoperative pain.