Chemical fingerprinting and bioactivity of Amazonian Ecuador Croton lechleri Müll. Arg. (Euphorbiaceae) stem bark essential oil: A new functional food ingredient?

► Chemistry and bioactivities of C. lechleri bark essential oil have been investigated. ► Combined GC, GCMS and NMR showed sesquiterpenes as the most abundant compounds. ► TLC-bioautography evidenced calacorenes and sesquicineole as the most bioactive. ► Antimutagenic properties of the whole essential oil were particularly relevant. ► The data suggest possible uses of C. lechleri bark essential oil as food ingredient.