Two dimensional difference gel electrophoresis analysis of cerebrospinal fluid in tuberculous meningitis patients

► First cerebrospinal fluid proteomic study in tuberculous meningitis. ► Identification of differentially expressed proteins of human and mycobacterial origin by 2D DIGE and mass spectrometry. ► Validation of ALOX-5 and GFAP by western blot technique. ► Proposing ALOX-5 as potential biomarker for diagnosis of TBM.