کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10597111 | 981955 | 2013 | 34 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Characterization of polysaccharides with marked inhibitory effect on lipid accumulation in Pleurotus eryngii
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کلمات کلیدی
Pleurotus eryngiioxLDLnuclear magnetic resonance - رزونانس مغناطیسی هستهایLipid accumulation - تجمع لیپیدNMR - تشدید مغناطیسی هستهای Mushroom - قارچ یا ماشرومoxidized low density lipoprotein - لیپوپروتئین با چگالی کم اکسید شدهInfrared - مادون قرمز (فروسرخ)Polysaccharide - چندقندی ها یا پلیساکاریدهاHPLC - کروماتوگرافی مایعی کاراhigh-performance liquid chromatography - کروماتوگرافی مایعی کاراGas chromatography - کروماتوگرافی گازی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
Mushrooms have a great potential for the production of useful bioactive metabolites. To explore the bioactive compounds from edible mushrooms for interfering with the development of macrophage-derived foam cells, which is recognized as the hallmark of early atherosclerosis, eight types of mushrooms polysaccharides had been selected to be tested. Consequently, different mushrooms polysaccharides displayed diverse component profiles. Of polysaccharides that we tested, the Pleurotus eryngii polysaccharide had the strongest inhibitory effect on lipid accumulation. Furthermore, through fractionation of DEAE-52 and Sephadex G-100, the polysaccharide from P. eryngii had been successfully purified and identified. By the analysis of IR, GC, and HPLC, the purified polysaccharide was estimated to be 30-38Â kDa for the average molecular weight with the monosaccharide composition mainly composed of D-types of mannose, glucose and galactose. Findings presented in this report firstly provide direct evidence, which links the purified polysaccharide moiety with the biological function in foam-cell model.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 97, Issue 2, 12 September 2013, Pages 604-613
Journal: Carbohydrate Polymers - Volume 97, Issue 2, 12 September 2013, Pages 604-613
نویسندگان
Jingjing Chen, Yangyang Yong, Meichun Xing, Yifan Gu, Zhao Zhang, Shizhu Zhang, Ling Lu,