کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10609858 | 984736 | 2011 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Membranes of epitaxial-like packed, super aligned electrospun micron hollow poly(l-lactic acid) (PLLA) fibers
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
Novel epitaxial-like packed, super aligned, mono-layered hollow fibrous membranes were prepared by co-axial electrospinning technology. PLLA pellets were dissolved in solvent mixture of dichloromethane and dimethyl formamide (DCM/DMFÂ =Â 9:1) to prepare sheath solution dope with various concentrations (from 8 to 19Â wt.%). Aqueous solution of poly-ethylene glycol (PEG) was used as core solution dope. During the electrospinning process, dope concentrations and feed rate ratios were adjusted, separately, to evaluate the formation of resulting membranes. With lower shell solution concentration (from 8 to 15Â wt.%), the collected, flattened film showed arrangement of lower order. A stood-up film was clearly seen when concentration increased to 17Â wt.% and higher. As the collecting time went longer, these fibers piled up and eventually, stood up as a thin film from the surface of collector. Increasing flow rate ratio (FRR) also resulted similar outcomes and verify the cause of this phenomenon. After washing with water, scanning electron microscopy (SEM) revealed sheets of mono-layered, micron-sized hollow fiber arrays which were well aligned and tightly packed, just like the epitaxial growth of some semiconducting materials. These perfectly aligned and tightly packed hollow fiber arrays can be considered as highly anisotropic scaffolds that mimic tissue structures, such as nerve tissue, vascular structure as well as other application.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 882-892
Journal: European Polymer Journal - Volume 47, Issue 5, May 2011, Pages 882-892
نویسندگان
Keng-Liang Ou, Chin-Sung Chen, Li-Hsiang Lin, Jen-Chieh Lu, Yao-Chi Shu, Wen-Chin Tseng, Jen-Chang Yang, Sheng-Yang Lee, Chien-Chung Chen,