کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10692691 | 1019732 | 2005 | 11 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Bone microstructure and elastic tissue properties are reflected in QUS axial transmission measurements
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
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چکیده انگلیسی
Accurate clinical interpretation of the sound velocity derived from axial transmission devices requires a detailed understanding of the propagation phenomena involved and of the bone factors that have an impact on measurements. In the low megahertz range, ultrasonic propagation in cortical bone depends on anisotropic elastic tissue properties, porosity and the cortical geometry (e.g., thickness). We investigated 10 human radius samples from a previous biaxial transmission study using a 50-MHz scanning acoustic microscope (SAM) and synchrotron radiation microcomputed tomography. The relationships between low-frequency axial transmission sound speed at 1 and 2 MHz, structural properties (cortical width Ct.Wi, porosity, Haversian canal density and material properties (acoustic impedance, mineral density) on site-matched cross-sections were investigated. Significant linear multivariate regression models (1 MHz: R2 = 0.84, p < 10â4, root-mean-square error (RMSE) = 38 m/s, 2 MHz: R2 = 0.65, p < 10â4, RMSE = 48 m/s) were found for the combination of Ct.Wi with porosity and impedance. A new model was derived that accounts for the nonlinear dispersion relation with Ct.Wi and predicts axial transmission velocities measured at different ultrasonic frequencies (R2 = 0.69, p < 10â4, RMSE = 52 m/s). (E-mail: kay.raum@medizin.uni-halle.de)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 9, September 2005, Pages 1225-1235
Journal: Ultrasound in Medicine & Biology - Volume 31, Issue 9, September 2005, Pages 1225-1235
نویسندگان
Kay Raum, Ingrid Leguerney, Florent Chandelier, Emmanuel Bossy, Maryline Talmant, Amena Saïed, Françoise Peyrin, Pascal Laugier,