کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10737982 1046674 2012 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی سالمندی
پیش نمایش صفحه اول مقاله
RNA oxidation catalyzed by cytochrome c leads to its depurination and cross-linking, which may facilitate cytochrome c release from mitochondria
چکیده انگلیسی
► We studied RNA oxidation catalyzed by either Fe(II)/ascorbate/H2O2 or cyt c/H2O2. ► We found that multiple oxidation markers are essential to assess RNA oxidation. ► RNA forms cross-linked complexes with cyt c during cyt c-catalyzed oxidation. ► Cyt c release from cardiolipin-containing liposomes is facilitated by RNA-cyt c cross-linking.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Free Radical Biology and Medicine - Volume 53, Issue 4, 15 August 2012, Pages 854-862
نویسندگان
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