Efficient isolation of specific genomic regions and identification of associated proteins by engineered DNA-binding molecule-mediated chromatin immunoprecipitation (enChIP) using CRISPR

- We developed enChIP for purification of specific genomic regions.
- enChIP using the CRISPR system efficiently isolates specific genomic regions.
- enChIP-mass spectrometry (enChIP-MS) identified proteins associated with those loci.