Eicosapentaenoic acid facilitates the folding of an outer membrane protein of the psychrotrophic bacterium, Shewanella livingstonensis Ac10

► Eicosapentaenoic acid (EPA) plays important roles in various organisms. ► Functions of phospholipids containing EPA (EPA-PLs) in protein folding were analyzed. ► Folding of a bacterial outer membrane protein was facilitated by EPA-PLs. ► Formation of the secondary structure of the protein was facilitated by EPA-PLs.