NHR-23 dependent collagen and hedgehog-related genes required for molting

► NHR-23 is a critical regulator of nematode development and molting. ► The manuscript characterizes the loss-of-function phenotype of an nhr-23 mutant. ► Whole genome expression analysis identifies new potential targets of NHR-23. ► Hedgehog-related genes are identified as NHR-23 dependent genes. ► New link between sterol mediated signaling and regulation by NHR-23 is found.