Effect of collagen I and fibronectin on the adhesion, elasticity and cytoskeletal organization of prostate cancer cells

► Depending on the metastatic origin, prostate cancer cells differ in their affinity to COL1. ► COL1 affects specifically the F-actin and cell elasticity of bone-derived prostate cancer cells. ► Cell elasticity can be used as a biomarker for cancer cells from different metastases.