Unusual subcellular confinement of the fragile X mental retardation protein (FMRP) in circulating human platelets: Complete polyribosome dissociation

► FMRP level in platelets is more similar to mRNA-binding proteins (PABP1 and FXR2P) than ribosomal proteins. ► FMRP is not associated with polyribosomes in circulating blood platelets. ► Platelets represent a simple biological system to study FMRP function.