MiR-214 reduces cell survival and enhances cisplatin-induced cytotoxicity via down-regulation of Bcl2l2 in cervical cancer cells

► MiR-214 reduces cell survival, induces apoptosis and enhances cisplatin-induced cytotoxicity. ► Bcl2l2 is a direct functional target gene of miR-214. ► MiR-214-induced apoptosis is related with Bax, caspase-9, caspase-8 and caspase-3. ► MiR-214 is regulated by DNA methylation and histone deacetylation.