Vaccine potential of recombinant saposin-like protein 2 against Fasciolosis gigantica in mice

- Recombinant saposin-like protein 2 (rFgSAP-2) exhibited vaccine potential against F. gigantica infection in mice.
- Vaccination with rFgSAP-2 showed high levels of protection at 76.4-78.5%.
- Vaccination with rFgSAP-2 showed a mixed Th1/Th2 response with Th2 predominating.
- The level of IgG1 was highly correlated with the reduced numbers of worms.