کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10966346 | 1102775 | 2013 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids Protection against avian necrotic enteritis after immunisation with NetB genetic or formaldehyde toxoids](/preview/png/10966346.png)
چکیده انگلیسی
NetB (necrotic enteritis toxin B) is a recently identified β-pore-forming toxin produced by Clostridium perfringens. This toxin has been shown to play a major role in avian necrotic enteritis. In recent years, a dramatic increase in necrotic enteritis has been observed, especially in countries where the use of antimicrobial growth promoters in animal feedstuffs has been banned. The aim of this work was to determine whether immunisation with a NetB toxoid would provide protection against necrotic enteritis. The immunisation of poultry with a formaldehyde NetB toxoid or with a NetB genetic toxoid (W262A) resulted in the induction of antibody responses against NetB and provided partial protection against disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 31, Issue 37, 20 August 2013, Pages 4003-4008
Journal: Vaccine - Volume 31, Issue 37, 20 August 2013, Pages 4003-4008
نویسندگان
Sérgio P. Fernandes da Costa, Dorien Mot, Monika Bokori-Brown, Christos G. Savva, Ajit K. Basak, Filip Van Immerseel, Richard W. Titball,