Virus-like particles displaying envelope domain III of dengue virus type 2 induce virus-specific antibody response in mice

► Fusion antigen with dengue virus EDIII in c/e1 loop of HBV core antigen created. ► Yeast-expressed fusion antigen assembled into virus-like particles. ► EDIII moiety on chimeric virus-like particle was accessible to specific antibodies. ► Chimeric virus-like particles induced dengue virus-specific antibody response in mice.