Evaluation of protection in a mouse model after vaccination with Mycobacterium avium subsp. paratuberculois protein cocktails

► Study conducted to identify candidates for development of improved vaccines for paratuberculosis. ► Mouse infection model used to evaluate proteins as vaccines. ► MAP proteins reduced tissue colonization after infection. ► Infection and vaccination invoked immune responses in mice. ► MAP proteins are useful vaccine candidates for paratuberculosis.