Kinetic and HPV infection effects on cross-type neutralizing antibody and avidity responses induced by Cervarix®

► Evaluated kinetics of Cervarix®-induced neutralization and avidity antibodies. ► Evaluated effects of homologous HPV infection on Cervarix®-induced antibody levels. ► 3 doses of Cervarix® induces significant levels of vaccine-related HPV antibodies. ► HPV-16 avidity has similar kinetic profile as neutralizing antibodies. ► Following 3 doses of Cervarix®, HPV infection had little effect on antibody levels.