Modelling the long-term persistence of neutralizing antibody in adults after one dose of live attenuated Japanese encephalitis chimeric virus vaccine

► We modelled antibody persistence after Japanese encephalitis vaccination. ► We considered vaccination with a live attenuated chimeric virus vaccine. ► We used 5 year follow-up data from adults having received a single vaccine dose. ► An initial period of rapid decline followed by much slower decline were identified. ► This analysis suggests that vaccine protects most adults for at least 10 years.