Protection of pigs against genital Chlamydia trachomatis challenge by parenteral or mucosal DNA immunization

► Evaluation of a MOMP-based Chlamydia trachomatis DNA vaccine in a pig model. ► Comparing mucosal and parenteral administration of the vaccine. ► Significant protection against a C. trachomatis infection was induced by mucosal vaccination. ► Parenteral immunization did not lead to significant protection.