کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10968620 | 1102896 | 2011 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
ایمونولوژی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice Immunisation with the glycolytic enzyme enolase confers effective protection against Candida albicans infection in mice](/preview/png/10968620.png)
چکیده انگلیسی
⺠Mice were immunized with recombinant enolase. ⺠High levels of IgG1 and IgG2a were induced in immune serum. Killing capacity of neutrophils enhanced after yeasts were opsonized with anti-serum. Fungal burdens reduced after antibody were passive transferred. ⺠Both Th1 cytokine IL-12 and Th2 cytokine IL-10 increased in immune serum. ⺠Enolase can effectively protect against systemic infection caused by two strains of Candida albicans differing in virulence in mice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vaccine - Volume 29, Issue 33, 26 July 2011, Pages 5526-5533
Journal: Vaccine - Volume 29, Issue 33, 26 July 2011, Pages 5526-5533
نویسندگان
Wen qing Li, Xu chu Hu, Xiaohuan Zhang, Yanping Ge, Sainan Zhao, Yan Hu, Robert B. Ashman,