Oral administration of myostatin-specific whole recombinant yeast Saccharomyces cerevisiae vaccine increases body weight and muscle composition in mice

► Whole recombinant yeast used as antigen delivery vehicle.► Oral delivery of the yeast stimulates mice specific immune response.► Using recombinant yeast immune-modulates endogenous protein function.► Oral delivery of the recombinant yeast expressing MSTN increases body weight.