Immunogenicity of one dose of Vero cell culture-derived Japanese encephalitis (JE) vaccine in adults previously vaccinated with mouse brain-derived JE vaccine

► We evaluated the immunogenicity of JE vaccine in previously vaccinated persons. ► We compared 1 dose in previously vaccinated subjects to 2 doses in vaccine-naïve. ► Previously vaccinated subjects had higher GMTs pre-vaccination and after each dose. ► Neutralizing antibody response was noninferior in previously vaccinated subjects.