کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10971583 1106481 2014 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The Drosophila IMD pathway in the activation of the humoral immune response
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
پیش نمایش صفحه اول مقاله
The Drosophila IMD pathway in the activation of the humoral immune response
چکیده انگلیسی
The IMD pathway signaling plays a pivotal role in the Drosophila defense against bacteria. During the last two decades, significant progress has been made in identifying the components and deciphering the molecular mechanisms underlying this pathway, including the means of bacterial sensing and signal transduction. While these findings have contributed to the understanding of the immune signaling in insects, they have also provided new insights in studying the mammalian NF-κB signaling pathways. Here, we summarize the current view of the IMD pathway focusing on how it regulates the humoral immune response of Drosophila.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental & Comparative Immunology - Volume 42, Issue 1, January 2014, Pages 25-35
نویسندگان
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